Development Level

Tbio 90 | 11,651
Tchem 12 | 1,388
Tclin 7 | 612
Tdark 4 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 4 | 298
hypoactivity 4 | 132
increased total body fat amoun... 4 | 134
abnormal bone structure 3 | 187
decreased body weight 3 | 161
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 135
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased circulating aspartat... 2 | 34
decreased circulating serum al... 2 | 82
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
increased circulating creatini... 2 | 38
increased lean body mass 2 | 172
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
limb grasping 2 | 41
mammalian phenotype 2 | 17
small superior vagus ganglion 2 | 74
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal locomotor activation 1 | 16
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal ovary morphology 1 | 7
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
cataract 1 | 92
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
male infertility 1 | 123
small adrenal glands 1 | 16
small testis 1 | 58
small uterus 1 | 3
thrombocytopenia 1 | 56

Disease

Carcinoma 87 | 11,493
psoriasis 62 | 6,694
ovarian cancer 58 | 8,520
medulloblastoma, large-cell 56 | 6,241
glioblastoma 55 | 5,792
atypical teratoid / rhabdoid tumor 51 | 5,112
osteosarcoma 49 | 7,950
ependymoma 47 | 4,679
lung cancer 41 | 4,740
adult high grade glioma 39 | 3,801
oligodendroglioma 36 | 2,850
Astrocytoma, Pilocytic 35 | 3,081
Breast cancer 35 | 3,578
group 3 medulloblastoma 35 | 4,104
Kidney cancer 34 | 2,613
lung carcinoma 33 | 2,843
pituitary cancer 32 | 1,972
primitive neuroectodermal tumor 30 | 3,035
astrocytic glioma 29 | 2,597
malignant mesothelioma 28 | 3,232
subependymal giant cell astrocytoma 28 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Cancer 24 | 2,499
Schizophrenia 24 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
non-small cell lung cancer 24 | 2,890
pancreatic cancer 24 | 2,398
Epilepsy 23 | 792
interstitial cystitis 23 | 2,312
invasive ductal carcinoma 23 | 2,951
Pick disease 22 | 1,894
Autosomal recessive predisposition 21 | 1,442
cystic fibrosis 21 | 1,696
Autistic Disorder 19 | 364
breast carcinoma 19 | 1,638
Intellectual disability 18 | 1,016
group 4 medulloblastoma 18 | 1,855
tuberculosis 18 | 2,010
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
Seizures 17 | 596
colon cancer 17 | 1,478
Short stature 16 | 531
lung adenocarcinoma 15 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
ductal carcinoma in situ 14 | 1,745
Muscle hypotonia 13 | 571
diabetes mellitus 13 | 1,728
Bipolar Disorder 12 | 666
Dull intelligence 12 | 645
Liver cancer 12 | 604
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
pediatric high grade glioma 12 | 1,064
Alzheimer's disease 11 | 658
Down syndrome 11 | 499
Parkinson's disease 11 | 392
adrenocortical carcinoma 11 | 1,428
gastric carcinoma 11 | 807
juvenile dermatomyositis 11 | 1,187
medulloblastoma 11 | 720
nasopharyngeal carcinoma 11 | 1,058
ulcerative colitis 11 | 1,819
Small head 10 | 374
active Crohn's disease 10 | 922
cutaneous lupus erythematosus 10 | 1,057
progressive supranuclear palsy 10 | 676
Cerebellar Ataxia 9 | 304
Melanoma 9 | 711
acute quadriplegic myopathy 9 | 1,158
primary pancreatic ductal adenocarcinoma 9 | 1,109
Alcoholic Intoxication, Chronic 8 | 289
Atopic dermatitis 8 | 952
Cleft Palate 8 | 271
Rheumatoid arthritis 8 | 1,191
active ulcerative colitis 8 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
spina bifida 8 | 1,074
Acquired metabolic disease 7 | 336
Blepharoptosis 7 | 231
Breast Neoplasms 7 | 445
Chronic Lymphocytic Leukemia 7 | 262
Cryptorchidism 7 | 296
Delayed bone age 7 | 136
Duchenne muscular dystrophy 7 | 601
Glaucoma 7 | 239
Motor delay 7 | 147
Multiple Sclerosis 7 | 540
Neoplasm Invasiveness 7 | 161
No development of motor milestones 7 | 147
Nystagmus 7 | 317
Strabismus 7 | 270
astrocytoma 7 | 1,146
esophageal adenocarcinoma 7 | 737
Congenital hypoplasia of penis 6 | 176
Prostatic Neoplasms 6 | 495

Tissue

Endocrine System 105 | 18,159
Nervous System 105 | 16,725
Digestive Tract 104 | 17,369
Female tissues 102 | 17,400
Skin and soft tissues 101 | 17,230
Male tissues 97 | 17,142
Urinary Tract 96 | 16,678
Blood and immune system 93 | 16,909
Liver and Pancreas 93 | 16,750
Respiratory system 91 | 16,393
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 24 | 4,145
Transcription Factor 21 | 1,400
Kinase 10 | 634
GPCR 4 | 408
Ion Channel 3 | 344
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

GO Process

central nervous system develop... 113 | 113
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Platelet-derived growth factor C PDGFC Tbio Non-IDG -2.03910 120.6 226
Ankyrin repeat and LEM domain-containing protein 2 ANKLE2 Tbio Non-IDG -1.07238 11.8 76
Endophilin-A1 SH3GL2 Tbio Non-IDG -1.79540 59.9 248
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.03962 9.87 97
Neuronal PAS domain-containing protein 1 NPAS1 Tbio Transcription Factor -0.85546 7.62 136
Neuronal PAS domain-containing protein 2 NPAS2 Tbio Transcription Factor -1.91320 81.4 182
Neuronal migration protein doublecortin DCX Tbio Non-IDG -3.03115 946.3 449
Calcipressin-1 RCAN1 Tbio Non-IDG -2.34820 254.4 412
Gamma-2-syntrophin SNTG2 Tbio Non-IDG -1.54819 34.8 66
Hyaluronan and proteoglycan link protein 3 HAPLN3 Tdark Non-IDG -0.45193 2.52 98