Development Level

Tbio 90 | 10,625
Tchem 14 | 1,890
Tclin 7 | 602
Tdark 6 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 4 | 226
decreased lean body mass 4 | 195
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating serum al... 3 | 79
embryonic lethality prior to t... 3 | 187
abnormal bone structure 2 | 131
abnormal eye morphology 2 | 38
abnormal locomotor activation 2 | 26
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating triglyce... 2 | 83
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased circulating creatini... 2 | 29
increased mean corpuscular vol... 2 | 91
limb grasping 2 | 35
short tibia 2 | 82
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
decreased B cell number 1 | 30
decreased IgE level 1 | 3
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased pro-B cell number 1 | 2
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
female infertility 1 | 34
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased body length 1 | 20
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 24
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased prepulse inhibition 1 | 21
increased pro-B cell number 1 | 1
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
short snout 1 | 4
shortened head 1 | 2
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

psoriasis 66 | 6,685
ovarian cancer 59 | 8,484
medulloblastoma, large-cell 57 | 6,234
glioblastoma 56 | 5,572
osteosarcoma 53 | 7,933
lung cancer 39 | 4,466
atypical teratoid / rhabdoid tumor 38 | 4,369
oligodendroglioma 37 | 2,849
lung carcinoma 36 | 2,844
pilocytic astrocytoma 36 | 3,086
pituitary cancer 33 | 1,972
Carcinoma 31 | 2,147
pediatric high grade glioma 31 | 2,712
primitive neuroectodermal tumor 31 | 3,031
malignant mesothelioma 29 | 3,162
ependymoma 28 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
subependymal giant cell astrocytoma 28 | 2,287
Breast cancer 26 | 3,094
interstitial cystitis 26 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
non-small cell lung cancer 24 | 2,798
Cancer 23 | 2,346
Pick disease 23 | 1,893
invasive ductal carcinoma 23 | 2,950
cystic fibrosis 22 | 1,665
adult high grade glioma 21 | 2,148
group 3 medulloblastoma 21 | 2,254
pancreatic cancer 21 | 2,300
astrocytic glioma 20 | 2,241
sonic hedgehog group medulloblastoma 20 | 1,482
colon cancer 18 | 1,475
group 4 medulloblastoma 18 | 1,875
posterior fossa group A ependymoma 18 | 1,511
Autistic Disorder 17 | 320
astrocytoma 17 | 1,493
lung adenocarcinoma 17 | 2,713
atypical teratoid/rhabdoid tumor 16 | 1,095
breast carcinoma 16 | 1,614
tuberculosis 16 | 1,557
Intellectual disability 15 | 573
ductal carcinoma in situ 14 | 1,745
Down syndrome 13 | 548
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
ulcerative colitis 13 | 2,087
cutaneous lupus erythematosus 12 | 1,056
diabetes mellitus 12 | 1,663
gastric carcinoma 12 | 832
Epilepsy 11 | 346
Parkinson's disease 11 | 364
active Crohn's disease 11 | 918
juvenile dermatomyositis 11 | 1,189
medulloblastoma 11 | 1,524
nasopharyngeal carcinoma 11 | 1,056
primary pancreatic ductal adenocarcinoma 11 | 1,271
Alzheimer's disease 10 | 644
adrenocortical carcinoma 10 | 1,427
progressive supranuclear palsy 10 | 674
Atopic dermatitis 9 | 944
acute quadriplegic myopathy 9 | 1,157
esophageal adenocarcinoma 9 | 737
spina bifida 9 | 1,064
Rheumatoid Arthritis 8 | 1,160
active ulcerative colitis 8 | 477
Duchenne muscular dystrophy 7 | 602
Schizophrenia 7 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
Mammary Neoplasms 6 | 410
Multiple Sclerosis 6 | 498
Neoplasm Invasiveness 6 | 127
Neurodegenerative disease 6 | 383
Prostatic Neoplasms 6 | 471
Vascular disease 6 | 281
nephrosclerosis 6 | 329
posterior fossa group B ependymoma 6 | 1,530
primary Sjogren syndrome 6 | 789
Amyotrophic Lateral Sclerosis 5 | 431
Bipolar Disorder 5 | 266
Cerebrovascular disease 5 | 231
Cleft palate 5 | 125
Craniofacial Abnormalities 5 | 147
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Microphthalmia 5 | 78
aldosterone-producing adenoma 5 | 664
dermatomyositis 5 | 933
facioscapulohumeral dystrophy 5 | 286
fibroadenoma 5 | 557
Asthma 4 | 349
Becker muscular dystrophy 4 | 187
Colonic Neoplasms 4 | 126
Multiple myeloma 4 | 1,327
Waldenstrons macroglobulinemia 4 | 765
chronic lymphosyte leukemia 4 | 232
hereditary spastic paraplegia 4 | 313
limb girdle muscular dystrophy 2A 4 | 156
mucosa-associated lymphoid tissue lymphoma 4 | 480
periodontitis 4 | 269
tuberculosis and treatment for 6 months 4 | 686
urothelial carcinoma 4 | 318

Tissue

Endocrine System 117 | 18,512
Female tissues 117 | 18,647
Nervous System 117 | 18,561
Digestive Tract 116 | 18,473
Skin and soft tissues 116 | 18,115
Urinary Tract 116 | 18,444
Male tissues 115 | 17,969
Liver and Pancreas 114 | 18,136
Blood and immune system 113 | 17,995
Cardiovascular System 113 | 17,958
Respiratory system 110 | 17,484

Target Family

Non-IDG 51 | 11,971
Enzyme 25 | 4,146
Transcription Factor 21 | 1,400
Kinase 10 | 634
GPCR 4 | 406
Ion Channel 3 | 341
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

GO Process

central nervous system develop... 117 | 117
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.33707 243.8 508
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Serine/threonine-protein kinase DCLK1 DCLK1 Tchem Kinase -1.97724 113.9 288
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
NEDD4-like E3 ubiquitin-protein ligase WWP1 WWP1 Tbio Enzyme -1.57709 42.8 121
Nestin NES Tbio Non-IDG -3.33502 2122.7 622
DNA ligase 4 LIG4 Tbio Enzyme -2.11773 136.0 194
Cytochrome c oxidase subunit 7B, mitochondrial COX7B Tbio Enzyme -0.60140 3.69 49
Versican core protein VCAN Tbio Non-IDG -2.85549 756.2 159