Development Level

Tbio 6 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
increased T cell number 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
Rheumatoid arthritis 3 | 1,191
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Cancer 2 | 2,499
Depressive disorder 2 | 409
Leprosy 2 | 73
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Parkinson Disease 2, Autosomal Recessive Juvenile 2 | 3
Parkinson's disease 2 | 392
acute myeloid leukemia 2 | 783
atypical teratoid / rhabdoid tumor 2 | 5,112
group 4 medulloblastoma 2 | 1,855
nasopharyngeal carcinoma 2 | 1,058
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Abnormality of metabolism/homeostasis 1 | 134
Adult onset 1 | 82
Amblyopia 1 | 38
Amyotrophic lateral sclerosis 1 | 451
Anisometropia 1 | 14
Anxiety 1 | 136
Anxiety disease 1 | 113
Astigmatism 1 | 54
Axenfeld-Rieger syndrome 1 | 14
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Blindness 1 | 88
Bradykinesia 1 | 34
Bronchioloalveolar Adenocarcinoma 1 | 14
Coloboma 1 | 51
Colonic Neoplasms 1 | 142
Congenital aphakia 1 | 6
Corneal dystrophy 1 | 24
Corneal edema 1 | 14
Deglutition Disorders 1 | 132
Dementia 1 | 175
Dysarthria 1 | 192
Dysgerminoma 1 | 11
Dyspnea 1 | 76
Dystonia 1 | 164
Dystonic disease 1 | 106
Ectropion 1 | 38
Excessive tearing 1 | 12
Fatigable weakness of respiratory muscles 1 | 28
Fatigue 1 | 182
Frontotemporal dementia 1 | 51
Generalized muscle weakness 1 | 57
Glaucoma, Open-Angle 1 | 11
Gliosis in the substantia nigra 1 | 3
Huntington's disease 1 | 76
Hyperopia 1 | 70
Hyperreflexia 1 | 209
Manganese Poisoning 1 | 11
Memory Disorders 1 | 40
Microphthalmia 1 | 76
Mood swings 1 | 77
Multiple system atrophy 1 | 29
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Muscle Spasticity 1 | 195
Muscle Weakness 1 | 170
Myopia 1 | 176
Neoplasms 1 | 63
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy 1 | 261
Ocular hypertension 1 | 42
Osteitis Deformans 1 | 11
Ovarian Cysts 1 | 41
Ovarian Neoplasms 1 | 102
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paget's disease of bone 1 | 36
Pain 1 | 103
Paralysed 1 | 42
Paratyphoid fever 1 | 10
Parkinson Disease 1 | 64
Parkinsonian Disorders 1 | 56
Pertussis 1 | 20
Postural instability 1 | 19
Respiratory Failure 1 | 104
Retinal Detachment 1 | 51
Skeletal muscle atrophy 1 | 139
Thalassemia 1 | 53
Toxic encephalopathy 1 | 141
Tremor 1 | 113
Uveitis 1 | 103
Xerostomia 1 | 42
muscle degeneration 1 | 139
primary open angle glaucoma 1 | 16

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Process

cellular response to unfolded ... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane 7 superfamily member 3 TM7SF3 Tdark Non-IDG -0.21821 2.12 55
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
E3 ubiquitin-protein ligase parkin PRKN Tbio Enzyme -2.99618 1004.1 533
Parkin coregulated gene protein PACRG Tbio Non-IDG -2.22175 173.2 128
Optineurin OPTN Tbio Non-IDG -3.20847 1590.6 247
Rhomboid-related protein 4 RHBDD1 Tbio Enzyme -0.96627 10.1 47
Death domain-associated protein 6 DAXX Tbio Non-IDG -2.33534 233.0 762