Development Level

Tbio 29 | 10,625
Tchem 16 | 1,890
Tclin 2 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

abnormal iris morphology 2 | 12
decreased body weight 2 | 174
increased or absent threshold ... 2 | 128
male infertility 2 | 62
narrow eye opening 2 | 15
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
corneal opacity 1 | 25
corneal vascularization 1 | 5
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
female infertility 1 | 34
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
irregularly shaped pupil 1 | 7
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
thrombocytosis 1 | 23

Disease

psoriasis 30 | 6,685
ovarian cancer 29 | 8,491
medulloblastoma, large-cell 25 | 6,234
osteosarcoma 22 | 7,933
lung cancer 20 | 4,473
Breast cancer 18 | 3,098
Cancer 18 | 2,346
atypical teratoid / rhabdoid tumor 16 | 4,369
glioblastoma 16 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
malignant mesothelioma 14 | 3,163
ependymoma 13 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
lung carcinoma 12 | 2,844
non-small cell lung cancer 12 | 2,798
ulcerative colitis 12 | 2,087
Obesity 11 | 616
diabetes mellitus 11 | 1,663
primitive neuroectodermal tumor 11 | 3,031
astrocytic glioma 10 | 2,241
cystic fibrosis 10 | 1,670
ductal carcinoma in situ 10 | 1,745
lung adenocarcinoma 10 | 2,714
pilocytic astrocytoma 10 | 3,086
medulloblastoma 9 | 1,524
oligodendroglioma 9 | 2,849
Pick disease 8 | 1,893
acute quadriplegic myopathy 8 | 1,157
adrenocortical carcinoma 8 | 1,427
colon cancer 8 | 1,475
pediatric high grade glioma 8 | 2,712
pituitary cancer 8 | 1,972
Rheumatoid Arthritis 7 | 1,170
breast carcinoma 7 | 1,614
pancreatic cancer 7 | 2,300
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 1,563
Atherosclerosis 6 | 275
Atopic dermatitis 6 | 944
Endometriosis 6 | 535
Metabolic syndrome X 6 | 155
Parkinson's disease 6 | 364
Prostatic Neoplasms 6 | 471
Stomach Neoplasms 6 | 282
chronic rhinosinusitis 6 | 512
dermatomyositis 6 | 966
fibroadenoma 6 | 557
group 4 medulloblastoma 6 | 1,875
primary pancreatic ductal adenocarcinoma 6 | 1,271
Carcinoma 5 | 2,147
Crohn's disease 5 | 304
Fatty liver disease 5 | 86
Lipid metabolism disorder 5 | 102
Mammary Neoplasms 5 | 410
active Crohn's disease 5 | 918
esophageal adenocarcinoma 5 | 737
group 3 medulloblastoma 5 | 2,254
spina bifida 5 | 1,064
Alzheimer's disease 4 | 644
Dementia 4 | 129
Diabetes Mellitus, Experimental 4 | 106
Down syndrome 4 | 548
Heart disease 4 | 279
Hyperglycemia 4 | 120
Vascular disease 4 | 281
acute myeloid leukemia 4 | 785
aldosterone-producing adenoma 4 | 664
astrocytoma 4 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
cutaneous lupus erythematosus 4 | 1,056
juvenile dermatomyositis 4 | 1,189
mucosa-associated lymphoid tissue lymphoma 4 | 480
posterior fossa group A ependymoma 4 | 1,511
Acute kidney injury 3 | 65
Amyotrophic Lateral Sclerosis 3 | 432
Anemia 3 | 252
Hypertension 3 | 293
Insulin Resistance 3 | 50
Kidney Failure, Chronic 3 | 45
Kidney disease 3 | 397
Lipodystrophy 3 | 32
Liver carcinoma 3 | 217
Liver disease 3 | 219
Multiple myeloma 3 | 1,327
Neoplasm Metastasis 3 | 138
Osteoporosis 3 | 259
Parkinson Disease 3 | 105
Peripheral Neuropathy 3 | 303
Stevens-Johnson syndrome 3 | 91
active ulcerative colitis 3 | 477
adult high grade glioma 3 | 2,148
atypical teratoid/rhabdoid tumor 3 | 1,095
hepatocellular carcinoma 3 | 550
interstitial cystitis 3 | 2,299
nasopharyngeal carcinoma 3 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
sonic hedgehog group medulloblastoma 3 | 1,482
Arthritis 2 | 248

Tissue

Blood and immune system 47 | 17,994
Cardiovascular System 47 | 17,957
Digestive Tract 47 | 18,472
Endocrine System 47 | 18,511
Female tissues 47 | 18,646
Liver and Pancreas 47 | 18,135
Male tissues 47 | 17,968
Nervous System 47 | 18,560
Skin and soft tissues 47 | 18,114
Urinary Tract 47 | 18,443
Respiratory system 46 | 17,483

Target Family

Non-IDG 23 | 11,969
Enzyme 11 | 4,146
Transcription Factor 7 | 1,400
Kinase 4 | 634
Epigenetic 2 | 242

GO Process

cellular response to starvatio... 47 | 47
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -2.99634 1000.8 1343
Beclin 1-associated autophagy-related key regulator ATG14 Tbio Non-IDG -1.60946 35.0 103
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.63610 415.3 337
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.28801 19.2 122
Growth arrest-specific protein 6 GAS6 Tbio Non-IDG -2.45622 294.9 165
Desmocollin-2 DSC2 Tbio Non-IDG -1.87316 75.7 124
Krueppel-like factor 10 KLF10 Tbio Transcription Factor -1.93274 82.9 166
Ras-related GTP-binding protein D RRAGD Tbio Non-IDG -0.79184 4.99 76
Ubiquitin-like modifier-activating enzyme ATG7 ATG7 Tbio Non-IDG -2.62012 364.0 366
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.44945 285.5 240