Development Level

Tchem 8 | 1,598
Tbio 7 | 11,445
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased T cell number 2 | 15
decreased circulating amylase ... 2 | 28
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal skin condition 1 | 6
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgG1 level 1 | 8
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
increased IgG2b level 1 | 1
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Cancer 14 | 2,499
Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
psoriasis 8 | 6,694
diabetes mellitus 6 | 1,728
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
ulcerative colitis 6 | 1,819
Breast Neoplasms 5 | 445
Cell Transformation, Neoplastic 5 | 97
Mammary Neoplasms 5 | 425
Neoplastic Cell Transformation 5 | 89
Schizophrenia 5 | 1,160
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
juvenile dermatomyositis 5 | 1,187
osteosarcoma 5 | 7,950
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Colonic Neoplasms 4 | 142
Diabetes Mellitus, Experimental 4 | 108
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Heart disease 4 | 306
Liver Cirrhosis, Experimental 4 | 769
Osteoporosis 4 | 363
Stomach Neoplasms 4 | 300
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
fibroadenoma 4 | 559
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
Amyotrophic lateral sclerosis 3 | 451
Blastic phase chronic myeloid leukemia 3 | 58
Breast cancer 3 | 3,578
Cardiomegaly 3 | 116
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Chronic phase chronic myeloid leukemia 3 | 45
Down syndrome 3 | 499
Hypertension 3 | 396
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 3 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 3 | 47
Prostatic Neoplasms 3 | 495
Short stature 3 | 531
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
Acquired scoliosis 2 | 281
Acromegaly 2 | 51
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Atherosclerosis 2 | 291
Atrial Fibrillation 2 | 124
Bipolar Disorder 2 | 666
Bladder Neoplasm 2 | 112
Brain Ischemia 2 | 110
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Hypercholesterolemia 2 | 44
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Lung disease 2 | 142
Melanoma 2 | 711
Mood Disorders 2 | 184
Neoplasm Invasiveness 2 | 161
Neurodegenerative disease 2 | 414
Pancreatic Neoplasm 2 | 85
Peripheral vascular disease 2 | 87
Reperfusion Injury 2 | 86
Seizures 2 | 596
Urinary Bladder Neoplasms 2 | 114
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
pulmonary arterial hypertension 2 | 75

Tissue

Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Nervous System 17 | 16,725
Blood and immune system 16 | 16,909
Respiratory system 16 | 16,393
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230

Target Family

Non-IDG 5 | 12,091
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Kinase 3 | 634
GPCR 1 | 408

GO Process

cellular response to peptide h... 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.51339 38.6 285
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Homeobox protein Nkx-6.1 NKX6-1 Tbio Transcription Factor -1.86592 62.8 247
G-protein coupled estrogen receptor 1 GPER1 Tchem GPCR -2.78141 706.4 288
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.47746 2989.0 646
Tyrosine-protein kinase CSK CSK Tchem Kinase -2.54736 271.3 547
Protein max MAX Tbio Transcription Factor -2.14268 110.6 398
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455