Development Level

Tbio 44 | 10,625
Tchem 12 | 1,890
Tclin 3 | 602
Tdark 2 | 7,003

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

decreased prepulse inhibition 3 | 52
increased mean corpuscular vol... 3 | 91
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased heart weight 2 | 44
increased mean corpuscular hem... 2 | 93
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
small testis 2 | 37
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sensory capabilities-... 1 | 3
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
absent testes 1 | 2
decreased IgG1 level 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lymphocyte cell numb... 1 | 9
decreased memory-marker CD4-po... 1 | 4
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased heart weight 1 | 37
increased neutrophil cell numb... 1 | 15
increased startle reflex 1 | 38
male infertility 1 | 62
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

osteosarcoma 32 | 7,933
ovarian cancer 30 | 8,491
Cancer 25 | 2,346
medulloblastoma, large-cell 25 | 6,234
psoriasis 23 | 6,685
glioblastoma 21 | 5,572
lung cancer 20 | 4,473
invasive ductal carcinoma 15 | 2,950
lung adenocarcinoma 15 | 2,714
Breast cancer 13 | 3,098
non-small cell lung cancer 13 | 2,798
Parkinson's disease 12 | 364
diabetes mellitus 12 | 1,663
malignant mesothelioma 12 | 3,163
tuberculosis 12 | 1,563
Neurodegenerative disease 11 | 383
atypical teratoid / rhabdoid tumor 11 | 4,369
breast carcinoma 11 | 1,614
ependymoma 11 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
oligodendroglioma 11 | 2,849
pancreatic cancer 11 | 2,300
pediatric high grade glioma 11 | 2,712
primitive neuroectodermal tumor 11 | 3,031
astrocytic glioma 10 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
Multiple myeloma 8 | 1,327
Pick disease 8 | 1,893
adrenocortical carcinoma 8 | 1,427
pituitary cancer 8 | 1,972
Obesity 7 | 616
acute myeloid leukemia 7 | 785
adult high grade glioma 7 | 2,148
astrocytoma 7 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
pilocytic astrocytoma 7 | 3,086
ulcerative colitis 7 | 2,087
Carcinoma 6 | 2,147
Parkinson Disease 6 | 105
Peripheral Neuropathy 6 | 303
Waldenstrons macroglobulinemia 6 | 764
colon cancer 6 | 1,475
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 2,254
hepatocellular carcinoma 6 | 550
juvenile dermatomyositis 6 | 1,189
medulloblastoma 6 | 1,524
non-small cell lung carcinoma 6 | 413
posterior fossa group B ependymoma 6 | 1,530
spina bifida 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis and treatment for 6 months 6 | 686
Alzheimer's disease 5 | 644
Amyotrophic Lateral Sclerosis 5 | 432
Atopic dermatitis 5 | 944
Mammary Neoplasms 5 | 410
Parkinsonian Disorders 5 | 23
Prostatic Neoplasms 5 | 471
acute quadriplegic myopathy 5 | 1,157
sonic hedgehog group medulloblastoma 5 | 1,482
Anemia 4 | 252
Diabetes Mellitus, Experimental 4 | 106
Endometriosis 4 | 535
Epilepsy 4 | 346
Huntington's disease 4 | 72
Hyperglycemia 4 | 120
Intellectual disability 4 | 573
Liver carcinoma 4 | 217
Schizophrenia 4 | 503
Toxic encephalopathy 4 | 131
Vascular disease 4 | 281
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,670
gastric cancer 4 | 436
interstitial cystitis 4 | 2,299
lung carcinoma 4 | 2,844
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
primary pancreatic ductal adenocarcinoma 4 | 1,271
Acquired metabolic disease 3 | 267
Dementia 3 | 129
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Down syndrome 3 | 548
Liver neoplasms 3 | 108
Nerve Degeneration 3 | 73
Osteoporosis 3 | 259
Rheumatoid Arthritis 3 | 1,170
Squamous cell carcinoma 3 | 96
Squamous cell carcinoma of esophagus 3 | 82
aldosterone-producing adenoma 3 | 664
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
mucosa-associated lymphoid tissue lymphoma 3 | 480
progressive supranuclear palsy 3 | 674
tuberculosis and treatment for 3 months 3 | 327
urothelial carcinoma 3 | 318

Tissue

Digestive Tract 61 | 18,472
Endocrine System 61 | 18,511
Female tissues 61 | 18,646
Liver and Pancreas 61 | 18,135
Nervous System 61 | 18,560
Cardiovascular System 60 | 17,957
Male tissues 60 | 17,968
Skin and soft tissues 60 | 18,114
Urinary Tract 60 | 18,443
Blood and immune system 59 | 17,994
Respiratory system 59 | 17,483

Target Family

Non-IDG 24 | 11,969
Enzyme 17 | 4,146
Kinase 7 | 634
Transcription Factor 6 | 1,400
Transporter 4 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

GO Process

cellular response to oxidative... 61 | 61
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.85874 681.4 264
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.56782 368.4 441
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -2.99634 1000.8 1343
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tchem Kinase -2.75634 590.2 473
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.74006 69.5 117
Thioredoxin-like protein 1 TXNL1 Tbio Non-IDG -2.31874 217.9 122
Selenoprotein N SELENON Tbio Non-IDG -1.93517 194.0 81
Fanconi anemia group C protein FANCC Tbio Non-IDG -2.81714 629.4 323
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.55826 362.4 351
Probable cation-transporting ATPase 13A2 ATP13A2 Tbio Transporter -2.00056 92.5 127