Development Level

Tbio 68 | 11,651
Tchem 15 | 1,388
Tclin 4 | 612
Tdark 4 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased prepulse inhibition 4 | 82
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating amylase ... 3 | 28
increased mean corpuscular vol... 3 | 92
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal bone mineralization 1 | 38
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal rib morphology 1 | 10
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
absent testes 1 | 6
cataract 1 | 92
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 52 | 11,493
ovarian cancer 49 | 8,520
osteosarcoma 48 | 7,950
Cancer 40 | 2,499
psoriasis 38 | 6,694
lung cancer 37 | 4,740
glioblastoma 35 | 5,792
medulloblastoma, large-cell 33 | 6,241
invasive ductal carcinoma 31 | 2,951
diabetes mellitus 28 | 1,728
non-small cell lung cancer 26 | 2,890
ependymoma 24 | 4,679
tuberculosis 24 | 2,010
atypical teratoid / rhabdoid tumor 23 | 5,112
lung adenocarcinoma 23 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
pancreatic cancer 21 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
adult high grade glioma 19 | 3,801
group 3 medulloblastoma 19 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Autosomal recessive predisposition 18 | 1,442
Breast cancer 18 | 3,578
malignant mesothelioma 18 | 3,232
Multiple myeloma 17 | 1,332
Neurodegenerative disease 17 | 414
Parkinson's disease 16 | 392
oligodendroglioma 16 | 2,850
Astrocytoma, Pilocytic 15 | 3,081
Schizophrenia 15 | 1,160
adrenocortical carcinoma 15 | 1,428
astrocytic glioma 15 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
primitive neuroectodermal tumor 15 | 3,035
breast carcinoma 14 | 1,638
interstitial cystitis 14 | 2,312
lung carcinoma 14 | 2,843
acute quadriplegic myopathy 13 | 1,158
Obesity 12 | 678
Toxic encephalopathy 12 | 141
Vascular disease 12 | 319
Amyotrophic lateral sclerosis 11 | 451
Atherosclerosis 11 | 291
Diabetes Mellitus, Experimental 11 | 108
Hypertension 11 | 396
Prostatic Neoplasms 11 | 495
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
Parkinsonian Disorders 10 | 56
Pick disease 10 | 1,894
Rheumatoid arthritis 10 | 1,191
ductal carcinoma in situ 10 | 1,745
group 4 medulloblastoma 10 | 1,855
Alzheimer's disease 9 | 658
Chemical and Drug Induced Liver Injury 9 | 195
Heart failure 9 | 162
Parkinson Disease 9 | 64
Waldenstrons macroglobulinemia 9 | 765
astrocytoma 9 | 1,146
cystic fibrosis 9 | 1,696
non-small cell lung carcinoma 9 | 317
pediatric high grade glioma 9 | 1,064
Carcinoma, Hepatocellular 8 | 228
Carcinoma, Non-Small-Cell Lung 8 | 107
Contact Dermatitis 8 | 81
Depressive disorder 8 | 409
Dermatitis, Contact 8 | 71
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
acute myeloid leukemia 8 | 783
colon cancer 8 | 1,478
hepatocellular carcinoma 8 | 547
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Diabetes Mellitus, Type 2 7 | 142
Epilepsy 7 | 792
Fatty Liver 7 | 70
Kidney cancer 7 | 2,613
Liver carcinoma 7 | 240
Necrosis 7 | 53
Nerve Degeneration 7 | 121
dermatomyositis 7 | 966
fibroadenoma 7 | 559
spina bifida 7 | 1,074
Anemia 6 | 365
Brain Ischemia 6 | 110
Down syndrome 6 | 499
Lung Neoplasms 6 | 232
Mental Depression 6 | 333
active ulcerative colitis 6 | 764
esophageal adenocarcinoma 6 | 737
nasopharyngeal carcinoma 6 | 1,058
pancreatic carcinoma 6 | 562

Tissue

Male tissues 91 | 17,142
Blood and immune system 90 | 16,909
Endocrine System 90 | 18,159
Urinary Tract 90 | 16,678
Digestive Tract 89 | 17,369
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Nervous System 89 | 16,725
Skin and soft tissues 89 | 17,230
Respiratory system 88 | 16,393
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 35 | 4,145
Kinase 7 | 634
Transcription Factor 6 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

cellular response to oxidative... 91 | 91
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.57346 40.9 157
Double-stranded RNA-binding protein Staufen homolog 1 STAU1 Tbio Non-IDG -2.24156 174.1 258
Thioredoxin, mitochondrial TXN2 Tbio Non-IDG -2.05954 125.2 260
NADPH oxidase 5 NOX5 Tbio Enzyme -1.82693 76.8 174
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Glutathione peroxidase 7 GPX7 Tbio Enzyme -1.44661 30.0 155
Transmembrane protein 161A TMEM161A Tdark Non-IDG 0.22 0.80 102
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.51854 3418.5 1661
Alpha-synuclein SNCA Tchem Non-IDG -3.63937 4224.9 1813