Development Level

Tchem 31 | 1,890
Tbio 20 | 10,625
Tclin 3 | 602
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
preweaning lethality, complete... 2 | 633
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal lens morphology 1 | 73
cataract 1 | 26
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased circulating amylase ... 1 | 24
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
female infertility 1 | 34
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
persistence of hyaloid vascula... 1 | 22
stereotypic behavior 1 | 3
trunk curl 1 | 15
urinary bladder obstruction 1 | 2

Disease

Cancer 35 | 2,346
osteosarcoma 34 | 7,933
ovarian cancer 33 | 8,484
psoriasis 33 | 6,685
glioblastoma 28 | 5,572
lung cancer 25 | 4,466
medulloblastoma, large-cell 24 | 6,234
lung adenocarcinoma 23 | 2,713
lung carcinoma 23 | 2,844
atypical teratoid / rhabdoid tumor 22 | 4,369
interstitial cystitis 21 | 2,299
ulcerative colitis 21 | 2,087
invasive ductal carcinoma 20 | 2,950
non-small cell lung cancer 20 | 2,798
pancreatic cancer 20 | 2,300
pilocytic astrocytoma 19 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
subependymal giant cell astrocytoma 18 | 2,287
Breast cancer 17 | 3,094
cystic fibrosis 17 | 1,665
malignant mesothelioma 17 | 3,162
tuberculosis 17 | 1,557
ependymoma 15 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
diabetes mellitus 14 | 1,663
posterior fossa group A ependymoma 13 | 1,511
Arthritis 12 | 248
Prostatic Neoplasms 12 | 471
group 4 medulloblastoma 12 | 1,875
pediatric high grade glioma 12 | 2,712
Asthma 11 | 349
Atherosclerosis 11 | 275
Lung disease 11 | 132
Mammary Neoplasms 11 | 410
Obesity 11 | 616
Rheumatoid Arthritis 11 | 1,160
adult high grade glioma 11 | 2,148
astrocytoma 11 | 1,493
cutaneous lupus erythematosus 11 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
primary pancreatic ductal adenocarcinoma 11 | 1,271
Atopic dermatitis 10 | 944
Heart disease 10 | 279
Hypersensitivity reaction type II disease 10 | 235
Inflammatory bowel disease 10 | 142
Kidney disease 10 | 396
Liver carcinoma 10 | 217
Multiple Sclerosis 10 | 498
adrenocortical carcinoma 10 | 1,427
pituitary cancer 10 | 1,972
Brain Ischemia 9 | 87
Dermatitis 9 | 107
Endometriosis 9 | 535
active Crohn's disease 9 | 918
nasopharyngeal carcinoma 9 | 1,056
oligodendroglioma 9 | 2,849
primitive neuroectodermal tumor 9 | 3,031
Carcinoma 8 | 2,147
Liver disease 8 | 219
Multiple myeloma 8 | 1,327
acute quadriplegic myopathy 8 | 1,157
dermatomyositis 8 | 933
juvenile dermatomyositis 8 | 1,189
sarcoidosis 8 | 358
spina bifida 8 | 1,064
Alzheimer's disease 7 | 644
Cardiomegaly 7 | 66
Coronary artery disease 7 | 240
Hypersensitivity 7 | 63
Inflammation 7 | 109
Lung Neoplasms 7 | 171
Pulmonary Fibrosis 7 | 66
Reperfusion Injury 7 | 84
astrocytic glioma 7 | 2,241
breast carcinoma 7 | 1,614
colon cancer 7 | 1,475
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 832
group 3 medulloblastoma 7 | 2,254
mucosa-associated lymphoid tissue lymphoma 7 | 480
primary Sjogren syndrome 7 | 789
Colorectal Neoplasms 6 | 217
Diabetes Mellitus, Experimental 6 | 106
Glomerulonephritis 6 | 36
Hyperglycemia 6 | 120
Hypertension 6 | 287
Hypertensive disease 6 | 193
Influenza 6 | 142
Osteoporosis 6 | 257
Pancreatitis 6 | 97
Pick disease 6 | 1,893
Pneumonia 6 | 133
Stomach Neoplasms 6 | 282
Vascular disease 6 | 281
pancreatic carcinoma 6 | 567
Allergic hypersensitivity disease 5 | 123
Eosinophilia 5 | 65
Myocardial Ischemia 5 | 169
Schizophrenia 5 | 501
acute myeloid leukemia 5 | 780

Tissue

Blood and immune system 55 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Urinary Tract 54 | 18,444

Target Family

Non-IDG 29 | 11,971
Transcription Factor 11 | 1,400
Enzyme 7 | 4,146
Kinase 5 | 634
GPCR 3 | 406
Transporter 1 | 473

GO Process

cellular response to organic c... 56 | 56
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Host cell factor 1 HCFC1 Tbio Non-IDG -2.50024 341.6 160
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
Krueppel-like factor 5 KLF5 Tchem Transcription Factor -2.15588 189.7 186
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.59556 4267.5 575
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.51321 325.2 174
Integrin alpha-6 ITGA6 Tchem Non-IDG -2.25486 168.8 756
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.50193 346.6 226