Development Level

Tbio 41 | 11,651
Tchem 26 | 1,388
Tclin 10 | 612
Tdark 1 | 6,593

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased circulating insulin ... 3 | 76
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased blood urea nitrogen ... 2 | 51
decreased circulating amylase ... 2 | 28
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
cataract 1 | 92
convulsive seizures 1 | 13
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased thermal nociceptive ... 1 | 2
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged uterus 1 | 11
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 50 | 11,493
Cancer 49 | 2,499
ovarian cancer 47 | 8,520
lung cancer 43 | 4,740
glioblastoma 42 | 5,792
osteosarcoma 34 | 7,950
psoriasis 33 | 6,694
lung carcinoma 31 | 2,843
pancreatic cancer 30 | 2,398
adult high grade glioma 29 | 3,801
malignant mesothelioma 29 | 3,232
medulloblastoma, large-cell 29 | 6,241
atypical teratoid / rhabdoid tumor 28 | 5,112
Breast cancer 27 | 3,578
ependymoma 26 | 4,679
non-small cell lung cancer 26 | 2,890
Astrocytoma, Pilocytic 24 | 3,081
diabetes mellitus 22 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
lung adenocarcinoma 22 | 2,716
subependymal giant cell astrocytoma 21 | 2,287
tuberculosis 21 | 2,010
group 3 medulloblastoma 20 | 4,104
primitive neuroectodermal tumor 20 | 3,035
cystic fibrosis 19 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
invasive ductal carcinoma 18 | 2,951
Hypertension 17 | 396
interstitial cystitis 17 | 2,312
Autosomal recessive predisposition 16 | 1,442
Hypertensive disease 16 | 292
Schizophrenia 16 | 1,160
breast carcinoma 16 | 1,638
primary pancreatic ductal adenocarcinoma 16 | 1,109
ulcerative colitis 16 | 1,819
Arthritis 15 | 290
Kidney disease 15 | 430
Vascular disease 15 | 319
pituitary cancer 15 | 1,972
Asthma 14 | 385
Heart disease 14 | 306
Hypersensitivity reaction type II disease 14 | 253
Prostatic Neoplasms 14 | 495
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
oligodendroglioma 14 | 2,850
Inflammatory bowel disease 13 | 151
Kidney cancer 13 | 2,613
Lung Neoplasms 13 | 232
astrocytic glioma 13 | 2,597
colon cancer 13 | 1,478
juvenile dermatomyositis 13 | 1,187
Pneumonia 12 | 174
Rheumatoid arthritis 12 | 1,191
adrenocortical carcinoma 12 | 1,428
astrocytoma 12 | 1,146
cutaneous lupus erythematosus 12 | 1,057
ductal carcinoma in situ 12 | 1,745
group 4 medulloblastoma 12 | 1,855
Bipolar Disorder 11 | 666
Heart failure 11 | 162
Inflammation 11 | 120
Lung disease 11 | 142
Multiple Sclerosis 11 | 540
Seizures 11 | 596
Stomach Neoplasms 11 | 300
gastric carcinoma 11 | 807
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Breast Neoplasms 10 | 445
Coronary artery disease 10 | 268
Depressive disorder 10 | 409
Liver disease 10 | 237
Mammary Neoplasms 10 | 425
Multiple myeloma 10 | 1,332
Obesity 10 | 678
Pick disease 10 | 1,894
esophageal adenocarcinoma 10 | 737
Adenocarcinoma 9 | 122
Anemia 9 | 365
Cerebrovascular disease 9 | 238
Down syndrome 9 | 499
Endometriosis 9 | 540
Fever 9 | 138
Liver Cirrhosis, Experimental 9 | 769
Mental Depression 9 | 333
active ulcerative colitis 9 | 764
dermatomyositis 9 | 966
pancreatic carcinoma 9 | 562
primary Sjogren syndrome 9 | 735
Cardiomyopathies 8 | 110
Colonic Neoplasms 8 | 142
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Diabetes Mellitus, Type 2 8 | 142
Epilepsy 8 | 792
Influenza 8 | 142
Intellectual disability 8 | 1,016
Neoplasm Metastasis 8 | 168
Reperfusion Injury 8 | 86
Short stature 8 | 531
active Crohn's disease 8 | 922
acute myeloid leukemia 8 | 783

Tissue

Endocrine System 77 | 18,159
Male tissues 77 | 17,142
Blood and immune system 76 | 16,909
Digestive Tract 76 | 17,369
Female tissues 76 | 17,400
Liver and Pancreas 76 | 16,750
Nervous System 76 | 16,725
Respiratory system 76 | 16,393
Urinary Tract 76 | 16,678
Skin and soft tissues 75 | 17,230
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Transporter 5 | 473
Ion Channel 4 | 344
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

cellular response to mechanica... 78 | 78
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.53932 4.30 895
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Natriuretic peptides A NPPA Tchem Non-IDG -3.25145 1788.9 509
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164