Development Level

Tchem 31 | 1,890
Tbio 29 | 10,625
Tclin 10 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

decreased circulating insulin ... 3 | 75
preweaning lethality, complete... 3 | 633
tremors 3 | 34
decreased bone mineral content 2 | 157
decreased circulating amylase ... 2 | 24
decreased circulating sodium l... 2 | 18
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased body weight 2 | 42
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 26
convulsive seizures 1 | 11
decreased CD4-positive, CD25-p... 1 | 24
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased pulmonary respirator... 1 | 4
decreased startle reflex 1 | 48
decreased thermal nociceptive ... 1 | 4
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased or absent threshold ... 1 | 128
increased thermal nociceptive ... 1 | 9
increased tidal volume 1 | 1
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
small superior vagus ganglion 1 | 20
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 43 | 8,484
Cancer 42 | 2,346
lung cancer 39 | 4,466
glioblastoma 37 | 5,572
osteosarcoma 31 | 7,933
psoriasis 31 | 6,685
lung carcinoma 29 | 2,844
pancreatic cancer 28 | 2,300
medulloblastoma, large-cell 27 | 6,234
pilocytic astrocytoma 25 | 3,086
malignant mesothelioma 23 | 3,162
non-small cell lung cancer 23 | 2,798
pediatric high grade glioma 23 | 2,712
Breast cancer 21 | 3,094
subependymal giant cell astrocytoma 21 | 2,287
ulcerative colitis 21 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
lung adenocarcinoma 20 | 2,713
primitive neuroectodermal tumor 20 | 3,031
atypical teratoid / rhabdoid tumor 19 | 4,369
diabetes mellitus 19 | 1,663
tuberculosis 18 | 1,557
cystic fibrosis 16 | 1,665
interstitial cystitis 16 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
invasive ductal carcinoma 16 | 2,950
primary pancreatic ductal adenocarcinoma 16 | 1,271
Arthritis 14 | 248
Carcinoma 14 | 2,147
Kidney disease 14 | 396
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
posterior fossa group A ependymoma 14 | 1,511
Asthma 13 | 349
Prostatic Neoplasms 13 | 471
breast carcinoma 13 | 1,614
juvenile dermatomyositis 13 | 1,189
pituitary cancer 13 | 1,972
Hypersensitivity reaction type II disease 12 | 235
Inflammatory bowel disease 12 | 142
Lung Neoplasms 12 | 171
Multiple Sclerosis 12 | 498
astrocytoma 12 | 1,493
Heart disease 11 | 279
Hypertensive disease 11 | 193
Rheumatoid Arthritis 11 | 1,160
Vascular disease 11 | 281
adult high grade glioma 11 | 2,148
cutaneous lupus erythematosus 11 | 1,056
gastric carcinoma 11 | 832
oligodendroglioma 11 | 2,849
Endometriosis 10 | 535
Hypertension 10 | 287
Inflammation 10 | 109
Stomach Neoplasms 10 | 282
adrenocortical carcinoma 10 | 1,427
colon cancer 10 | 1,475
ductal carcinoma in situ 10 | 1,745
esophageal adenocarcinoma 10 | 737
group 4 medulloblastoma 10 | 1,875
primary Sjogren syndrome 10 | 789
Coronary artery disease 9 | 240
Liver disease 9 | 219
Lung disease 9 | 132
Mammary Neoplasms 9 | 410
Multiple myeloma 9 | 1,327
Obesity 9 | 616
Pneumonia 9 | 133
astrocytic glioma 9 | 2,241
ependymoma 9 | 2,514
pancreatic carcinoma 9 | 567
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Adenocarcinoma 8 | 115
Alzheimer's disease 8 | 644
Cerebrovascular disease 8 | 231
Diabetes Mellitus, Experimental 8 | 106
Down syndrome 8 | 548
Influenza 8 | 142
Myocardial Infarction 8 | 126
Neoplasm Metastasis 8 | 138
Pick disease 8 | 1,893
Reperfusion Injury 8 | 84
active Crohn's disease 8 | 918
acute myeloid leukemia 8 | 780
dermatomyositis 8 | 933
group 3 medulloblastoma 8 | 2,254
medulloblastoma 8 | 1,524
Adenoma 7 | 165
Atherosclerosis 7 | 275
Cardiomyopathies 7 | 90
Chronic Lymphocytic Leukemia 7 | 242
Colonic Neoplasms 7 | 126
Dermatitis 7 | 107
Diabetes Mellitus, Non-Insulin-Dependent 7 | 157
IGA Glomerulonephritis 7 | 454
Toxic encephalopathy 7 | 131
atypical teratoid/rhabdoid tumor 7 | 1,095
gastric cancer 7 | 430
non-small cell lung carcinoma 7 | 413
sonic hedgehog group medulloblastoma 7 | 1,482
urothelial carcinoma 7 | 318

Tissue

Blood and immune system 69 | 17,995
Cardiovascular System 69 | 17,958
Female tissues 69 | 18,647
Liver and Pancreas 69 | 18,136
Male tissues 69 | 17,969
Digestive Tract 68 | 18,473
Endocrine System 68 | 18,512
Nervous System 68 | 18,561
Respiratory system 68 | 17,484
Skin and soft tissues 68 | 18,115
Urinary Tract 68 | 18,444

Target Family

Non-IDG 40 | 11,971
Enzyme 9 | 4,146
Kinase 9 | 634
Transcription Factor 4 | 1,400
Transporter 4 | 473
Ion Channel 2 | 341
Epigenetic 1 | 242
GPCR 1 | 406

GO Process

cellular response to mechanica... 70 | 70
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.80657 344.1 42
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
Interleukin-13 IL13 Tbio Non-IDG -3.26171 1774.2 682
Tumor necrosis factor receptor superfamily member 5 CD40 Tchem Non-IDG -3.44068 3018.0 1385
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.48343 339.1 259