Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal pancreas morphology 1 | 13
decreased circulating unsatura... 1 | 2
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Down syndrome 5 | 499
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
medulloblastoma, large-cell 5 | 6,241
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Autosomal recessive predisposition 4 | 1,442
Liver Cirrhosis, Experimental 4 | 769
Obesity 4 | 678
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
ulcerative colitis 4 | 1,819
Calcinosis 3 | 70
Duchenne muscular dystrophy 3 | 601
Fatty liver disease 3 | 103
Kidney cancer 3 | 2,613
Pneumonia 3 | 174
Splenomegaly 3 | 190
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
Arthritis 2 | 290
Atherosclerosis 2 | 291
Carcinoma, Non-Small-Cell Lung 2 | 107
Cardiomyopathy, Dilated 2 | 83
Cardiovascular system disease 2 | 246
Coronary Disease 2 | 25
Coronary artery disease 2 | 268
Coronary heart disease 2 | 16
Dyspnea 2 | 76
Epilepsy 2 | 792
Fatty Liver 2 | 70
Gaucher disease type 1 2 | 180
Hepatomegaly 2 | 285
Hypertensive disease 2 | 292
Immunologic Deficiency Syndromes 2 | 113
Lipid metabolism disorder 2 | 114
Liver Cirrhosis 2 | 181
Malaria 2 | 160
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Muscle hypotonia 2 | 571
Non-alcoholic Fatty Liver Disease 2 | 42
Seizures 2 | 596
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung carcinoma 2 | 317
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
Abnormality of the endocrine system 1 | 9
Basal ganglia calcification 1 | 27
Brain Neoplasms 1 | 33
Dyslipidemias 1 | 27
Ebola hemorrhagic fever 1 | 13
Endocrine System Diseases 1 | 11
Giant platelet (morphologic abnormality) 1 | 5
Idiopathic generalized epilepsy 1 | 14
Impaired left ventricular function 1 | 16
Left-Sided Heart Failure 1 | 16
Multiple endocrine neoplasia type 2A 1 | 20
PLASMODIUM FALCIPARUM BLOOD INFECTION LEVEL 1 | 4
Platelet Glycoprotein IV Deficiency 1 | 1
Polydipsia 1 | 15
Staphylococcal Infections 1 | 5
Thyroid Diseases 1 | 24

Tissue

Endocrine System 12 | 18,159
Liver and Pancreas 12 | 16,750
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 10 | 12,091
GPCR 1 | 408
Kinase 1 | 634

GO Process

cellular response to low-densi... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
CD81 antigen CD81 Tchem Non-IDG -2.77049 534.4 771
Extracellular calcium-sensing receptor CASR Tclin GPCR -3.22181 1714.9 441
Fibroblast growth factor 21 FGF21 Tbio Non-IDG -2.81854 777.4 443
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
High affinity immunoglobulin epsilon receptor subunit gamma FCER1G Tbio Non-IDG -2.03700 91.3 116
Integrin beta-1 ITGB1 Tclin Non-IDG -3.15400 1269.8 1956