Development Level

Tbio 61 | 10,625
Tchem 30 | 1,890
Tclin 17 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal behavior 3 | 226
abnormal retinal pigmentation 3 | 61
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal sleep behavior 2 | 63
decreased T cell number 2 | 31
decreased circulating serum al... 2 | 79
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
hypoactivity 2 | 89
immune system phenotype 2 | 17
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
vertebral fusion 2 | 23
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal eye morphology 1 | 38
abnormal eye posterior chamber... 1 | 3
abnormal femur morphology 1 | 14
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
decreased IgG1 level 1 | 4
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 2
decreased caudal vertebrae num... 1 | 49
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
increased bone mineral content 1 | 92
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 37
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
thin ventricular wall 1 | 5
thrombocytopenia 1 | 46

Disease

psoriasis 59 | 6,685
Cancer 55 | 2,346
osteosarcoma 52 | 7,933
ovarian cancer 52 | 8,484
lung cancer 49 | 4,466
glioblastoma 44 | 5,572
tuberculosis 42 | 1,557
ulcerative colitis 38 | 2,087
lung carcinoma 35 | 2,844
medulloblastoma, large-cell 32 | 6,234
pilocytic astrocytoma 32 | 3,086
invasive ductal carcinoma 30 | 2,950
malignant mesothelioma 30 | 3,162
interstitial cystitis 29 | 2,299
diabetes mellitus 28 | 1,663
pancreatic cancer 28 | 2,300
non-small cell lung cancer 27 | 2,798
cutaneous lupus erythematosus 26 | 1,056
atypical teratoid / rhabdoid tumor 25 | 4,369
cystic fibrosis 25 | 1,665
Asthma 24 | 349
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
lung adenocarcinoma 24 | 2,713
Multiple Sclerosis 23 | 498
Obesity 23 | 616
pediatric high grade glioma 23 | 2,712
Breast cancer 22 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
Kidney disease 21 | 396
Rheumatoid Arthritis 21 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
Arthritis 19 | 248
subependymal giant cell astrocytoma 19 | 2,287
Hypersensitivity reaction type II disease 18 | 235
Inflammatory bowel disease 18 | 142
astrocytoma 18 | 1,493
group 4 medulloblastoma 18 | 1,875
pituitary cancer 18 | 1,972
posterior fossa group A ependymoma 18 | 1,511
Atherosclerosis 17 | 275
adrenocortical carcinoma 17 | 1,427
Liver disease 16 | 219
colon cancer 16 | 1,475
Dermatitis 15 | 107
Mammary Neoplasms 15 | 410
Prostatic Neoplasms 15 | 471
primary Sjogren syndrome 15 | 789
Lung disease 14 | 132
breast carcinoma 14 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
primary pancreatic ductal adenocarcinoma 14 | 1,271
Carcinoma 13 | 2,147
Cerebrovascular disease 13 | 231
Heart disease 13 | 279
IGA Glomerulonephritis 13 | 454
Multiple myeloma 13 | 1,327
active Crohn's disease 13 | 918
adult high grade glioma 13 | 2,148
ductal carcinoma in situ 13 | 1,745
gastric carcinoma 13 | 832
head and neck cancer and chronic obstructive pulmonary disease 13 | 237
primitive neuroectodermal tumor 13 | 3,031
Allergic hypersensitivity disease 12 | 123
Coronary artery disease 12 | 240
Inflammation 12 | 109
Influenza 12 | 142
Metabolic syndrome X 12 | 155
Peripheral Neuropathy 12 | 303
Pneumonia 12 | 133
Reperfusion Injury 12 | 84
Vascular disease 12 | 281
juvenile dermatomyositis 12 | 1,189
oligodendroglioma 12 | 2,849
Crohn's disease 11 | 304
Human immunodeficiency virus infectious disease 11 | 92
Lung Neoplasms 11 | 171
Malaria 11 | 140
ependymoma 11 | 2,514
periodontitis 11 | 269
Atopic dermatitis 10 | 944
Drug-Induced Liver Injury 10 | 118
Peritonitis 10 | 37
Waldenstrons macroglobulinemia 10 | 765
head and neck cancer 10 | 270
nasopharyngeal carcinoma 10 | 1,056
non-small cell lung carcinoma 10 | 413
Alzheimer's disease 9 | 644
Brain Ischemia 9 | 87
Cholestasis 9 | 93
Crohn Disease 9 | 97
Down syndrome 9 | 548
Hypertension 9 | 287
Leishmaniasis 9 | 49
Myocardial Ischemia 9 | 169
aldosterone-producing adenoma 9 | 664
atypical teratoid/rhabdoid tumor 9 | 1,095
dermatomyositis 9 | 933
esophageal adenocarcinoma 9 | 737
mucosa-associated lymphoid tissue lymphoma 9 | 480
nephrosclerosis 9 | 329

Tissue

Digestive Tract 108 | 18,473
Female tissues 108 | 18,647
Nervous System 108 | 18,561
Respiratory system 108 | 17,484
Urinary Tract 108 | 18,444
Blood and immune system 107 | 17,995
Cardiovascular System 107 | 17,958
Endocrine System 107 | 18,512
Liver and Pancreas 107 | 18,136
Male tissues 105 | 17,969
Skin and soft tissues 105 | 18,115

Target Family

Non-IDG 61 | 11,971
Enzyme 16 | 4,146
Transcription Factor 11 | 1,400
Kinase 8 | 634
GPCR 5 | 406
Nuclear Receptor 5 | 48
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

cellular response to lipopolys... 108 | 108
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
A-kinase anchor protein 8 AKAP8 Tbio Enzyme -1.32097 22.6 240
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.48442 31.1 337
Endothelin B receptor EDNRB Tclin GPCR -3.24561 1672.0 289
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.16239 168.2 0
Tumor necrosis factor receptor superfamily member 5 CD40 Tchem Non-IDG -3.44068 3018.0 1385
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.80784 708.8 168
TNFAIP3-interacting protein 2 TNIP2 Tbio Non-IDG -1.26538 19.5 139