Development Level

Tbio 80 | 11,651
Tchem 27 | 1,388
Tclin 20 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
abnormal behavior 3 | 298
decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
decreased T cell number 2 | 15
decreased circulating amylase ... 2 | 28
decreased circulating serum al... 2 | 82
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
vertebral fusion 2 | 23
abnormal bone mineralization 1 | 38
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
decreased IgG1 level 1 | 8
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 3
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 82 | 11,493
psoriasis 68 | 6,694
Cancer 64 | 2,499
osteosarcoma 63 | 7,950
ovarian cancer 61 | 8,520
lung cancer 54 | 4,740
tuberculosis 51 | 2,010
glioblastoma 49 | 5,792
lung carcinoma 40 | 2,843
ulcerative colitis 40 | 1,819
medulloblastoma, large-cell 37 | 6,241
diabetes mellitus 36 | 1,728
malignant mesothelioma 36 | 3,232
adult high grade glioma 35 | 3,801
atypical teratoid / rhabdoid tumor 35 | 5,112
invasive ductal carcinoma 35 | 2,951
Astrocytoma, Pilocytic 34 | 3,081
non-small cell lung cancer 33 | 2,890
ependymoma 32 | 4,679
cystic fibrosis 30 | 1,696
interstitial cystitis 30 | 2,312
pancreatic cancer 30 | 2,398
Schizophrenia 29 | 1,160
lung adenocarcinoma 29 | 2,716
Obesity 28 | 678
cutaneous lupus erythematosus 28 | 1,057
Multiple Sclerosis 27 | 540
Rheumatoid arthritis 27 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
Asthma 26 | 385
group 3 medulloblastoma 26 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Kidney disease 25 | 430
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
Breast cancer 24 | 3,578
Inflammatory bowel disease 24 | 151
subependymal giant cell astrocytoma 23 | 2,287
Arthritis 21 | 290
Hypersensitivity reaction type II disease 21 | 253
Atherosclerosis 20 | 291
Liver Cirrhosis, Experimental 20 | 769
Kidney cancer 19 | 2,613
Liver disease 19 | 237
astrocytoma 19 | 1,146
colon cancer 19 | 1,478
Bipolar Disorder 18 | 666
adrenocortical carcinoma 18 | 1,428
pituitary cancer 18 | 1,972
Dermatitis 17 | 157
Heart disease 17 | 306
Breast Neoplasms 16 | 445
Inflammation 16 | 120
Lung disease 16 | 142
Mammary Neoplasms 16 | 425
Multiple myeloma 16 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Pneumonia 15 | 174
Prostatic Neoplasms 15 | 495
active Crohn's disease 15 | 922
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
primary Sjogren syndrome 15 | 735
primary pancreatic ductal adenocarcinoma 15 | 1,109
primitive neuroectodermal tumor 15 | 3,035
Autosomal recessive predisposition 14 | 1,442
Cerebrovascular disease 14 | 238
Crohn's disease 14 | 321
Hypertension 14 | 396
Vascular disease 14 | 319
active ulcerative colitis 14 | 764
head and neck cancer and chronic obstructive pulmonary disease 14 | 239
Arthritis, Rheumatoid 13 | 174
Chemical and Drug Induced Liver Injury 13 | 195
Depressive disorder 13 | 409
Malaria 13 | 160
juvenile dermatomyositis 13 | 1,187
mucosa-associated lymphoid tissue lymphoma 13 | 484
oligodendroglioma 13 | 2,850
Allergic hypersensitivity disease 12 | 126
Anemia 12 | 365
Coronary artery disease 12 | 268
Fever 12 | 138
Human immunodeficiency virus infectious disease 12 | 138
Influenza 12 | 142
Lung Neoplasms 12 | 232
Mental Depression 12 | 333
Reperfusion Injury 12 | 86
Vasculitis 12 | 80
Waldenstrons macroglobulinemia 12 | 765
group 4 medulloblastoma 12 | 1,855
periodontitis 12 | 293
Atopic dermatitis 11 | 952
Cholestasis 11 | 155
Leishmaniasis 11 | 47
Liver carcinoma 11 | 240
Myocardial Infarction 11 | 151
Peritonitis 11 | 43
gastric cancer 11 | 459
gastric carcinoma 11 | 807
nasopharyngeal carcinoma 11 | 1,058

Tissue

Blood and immune system 125 | 16,909
Digestive Tract 125 | 17,369
Endocrine System 125 | 18,159
Respiratory system 124 | 16,393
Skin and soft tissues 124 | 17,230
Urinary Tract 123 | 16,678
Female tissues 122 | 17,400
Liver and Pancreas 120 | 16,750
Male tissues 120 | 17,142
Nervous System 116 | 16,725
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 69 | 12,091
Enzyme 24 | 4,145
Transcription Factor 11 | 1,400
Kinase 9 | 634
GPCR 6 | 408
Nuclear Receptor 5 | 48
Transporter 2 | 473
Epigenetic 1 | 242

GO Process

cellular response to lipopolys... 127 | 127
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
CCAAT/enhancer-binding protein epsilon CEBPE Tbio Transcription Factor -1.71776 57.4 246
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075