Development Level

Tbio 74 | 11,445
Tchem 15 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased vertical activity 4 | 208
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal tooth morphology 2 | 24
cataract 2 | 92
decreased circulating total pr... 2 | 49
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
increased or absent threshold ... 2 | 101
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
absent pinna reflex 1 | 23
cyanosis 1 | 7
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased granulocyte number 1 | 6
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to o... 1 | 239
hydrops fetalis 1 | 1
increased body length 1 | 32
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased vertical activity 1 | 24
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
vertebral fusion 1 | 23

Disease

Carcinoma 62 | 11,493
ovarian cancer 57 | 8,520
psoriasis 46 | 6,694
medulloblastoma, large-cell 45 | 6,241
osteosarcoma 44 | 7,950
glioblastoma 42 | 5,792
lung cancer 39 | 4,740
atypical teratoid / rhabdoid tumor 37 | 5,112
group 3 medulloblastoma 36 | 4,104
ependymoma 33 | 4,679
Cancer 32 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
malignant mesothelioma 30 | 3,232
Breast cancer 28 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
invasive ductal carcinoma 26 | 2,951
lung carcinoma 24 | 2,843
pancreatic cancer 24 | 2,398
non-small cell lung cancer 22 | 2,890
primitive neuroectodermal tumor 22 | 3,035
adult high grade glioma 21 | 3,801
ulcerative colitis 21 | 1,819
astrocytic glioma 20 | 2,597
Astrocytoma, Pilocytic 19 | 3,081
interstitial cystitis 19 | 2,312
pituitary cancer 19 | 1,972
oligodendroglioma 18 | 2,850
tuberculosis 17 | 2,010
cystic fibrosis 16 | 1,696
lung adenocarcinoma 15 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Multiple myeloma 14 | 1,332
Schizophrenia 14 | 1,160
ductal carcinoma in situ 14 | 1,745
Pick disease 13 | 1,894
adrenocortical carcinoma 13 | 1,428
breast carcinoma 13 | 1,638
diabetes mellitus 13 | 1,728
juvenile dermatomyositis 13 | 1,187
nasopharyngeal carcinoma 13 | 1,058
primary pancreatic ductal adenocarcinoma 13 | 1,109
subependymal giant cell astrocytoma 13 | 2,287
dermatomyositis 12 | 966
Autosomal recessive predisposition 11 | 1,442
Kidney cancer 11 | 2,613
Obesity 11 | 678
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
aldosterone-producing adenoma 11 | 665
gastric carcinoma 11 | 807
pediatric high grade glioma 11 | 1,064
cutaneous lupus erythematosus 10 | 1,057
Multiple Sclerosis 9 | 540
esophageal adenocarcinoma 9 | 737
group 4 medulloblastoma 9 | 1,855
Bipolar Disorder 8 | 666
Epilepsy 8 | 792
Rheumatoid arthritis 8 | 1,191
colon cancer 8 | 1,478
fibroadenoma 8 | 559
Adenocarcinoma of lung 7 | 142
Myocardial Ischemia 7 | 169
astrocytoma 7 | 1,146
Alzheimer's disease 6 | 658
Anemia 6 | 365
Disease Models, Animal 6 | 155
Duchenne muscular dystrophy 6 | 601
Muscle hypotonia 6 | 571
pancreatic carcinoma 6 | 562
periodontitis 6 | 293
primary Sjogren syndrome 6 | 735
spina bifida 6 | 1,074
Amyotrophic lateral sclerosis 5 | 451
Arthritis 5 | 290
Atherosclerosis 5 | 291
Breast Neoplasms 5 | 445
Congenital deafness 5 | 185
Deafness 5 | 198
Down syndrome 5 | 499
Hearing Loss, Partial 5 | 185
Hyperglycemia 5 | 137
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Mammary Neoplasms 5 | 425
Toxic encephalopathy 5 | 141
Vascular disease 5 | 319
head and neck cancer 5 | 271
hearing impairment 5 | 199
medulloblastoma 5 | 720
Diabetes Mellitus, Type 2 4 | 142
Dull intelligence 4 | 645
Hepatomegaly 4 | 285
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
active Crohn's disease 4 | 922
chronic lymphosyte leukemia 4 | 204
chronic rhinosinusitis 4 | 512
non diabetic and post-ischemic heart failure 4 | 200
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 94 | 18,159
Skin and soft tissues 93 | 17,230
Blood and immune system 92 | 16,909
Digestive Tract 92 | 17,369
Female tissues 92 | 17,400
Liver and Pancreas 92 | 16,750
Male tissues 92 | 17,142
Nervous System 92 | 16,725
Urinary Tract 92 | 16,678
Respiratory system 91 | 16,393
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 26 | 4,145
Transcription Factor 15 | 1,400
Epigenetic 4 | 242
Kinase 3 | 634
TF/Epigenetic 3 | 38
Transporter 3 | 473
GPCR 2 | 408
Nuclear Receptor 2 | 48

GO Process

cellular response to leukemia ... 94 | 94
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Lysine-specific demethylase 3A KDM3A Tchem Epigenetic -1.83544 74.7 253
Lysosomal-associated transmembrane protein 5 LAPTM5 Tbio Non-IDG -1.07401 14.4 71
E3 ubiquitin-protein ligase RNF138 RNF138 Tbio Transcription Factor -1.08996 12.5 148
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677