Development Level

Tbio 17 | 10,625
Tchem 11 | 1,890
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 3 | 260
enlarged heart 2 | 111
increased exploration in new e... 2 | 56
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased circulating insulin ... 1 | 75
decreased grip strength 1 | 123
decreased rib number 1 | 59
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased body length 1 | 20
increased heart weight 1 | 37
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
small testis 1 | 37
straub tail 1 | 26
tremors 1 | 34

Disease

osteosarcoma 24 | 7,933
ovarian cancer 20 | 8,484
glioblastoma 18 | 5,572
lung cancer 16 | 4,466
medulloblastoma, large-cell 15 | 6,234
psoriasis 15 | 6,685
Cancer 14 | 2,346
malignant mesothelioma 13 | 3,162
pediatric high grade glioma 11 | 2,712
Breast cancer 10 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
invasive ductal carcinoma 9 | 2,950
non-small cell lung cancer 9 | 2,798
atypical teratoid / rhabdoid tumor 8 | 4,369
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
juvenile dermatomyositis 8 | 1,189
pancreatic cancer 8 | 2,300
acute quadriplegic myopathy 7 | 1,157
adrenocortical carcinoma 7 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
nasopharyngeal carcinoma 7 | 1,056
pilocytic astrocytoma 7 | 3,086
primitive neuroectodermal tumor 7 | 3,031
diabetes mellitus 6 | 1,663
ductal carcinoma in situ 6 | 1,745
oligodendroglioma 6 | 2,849
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Mammary Neoplasms 5 | 410
Prostatic Neoplasms 5 | 471
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,713
posterior fossa group A ependymoma 5 | 1,511
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Adenoma 4 | 165
Duchenne muscular dystrophy 4 | 602
Endometriosis 4 | 535
Lung Neoplasms 4 | 171
Obesity 4 | 616
Rheumatoid Arthritis 4 | 1,160
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
Acute kidney injury 3 | 65
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Arthritis 3 | 248
Bloom syndrome 3 | 30
Carcinoma 3 | 2,147
Diabetes Mellitus, Experimental 3 | 106
Gaucher disease type 1 3 | 171
HIV Infections 3 | 100
Heart disease 3 | 279
IGA Glomerulonephritis 3 | 454
Kidney disease 3 | 396
Lung disease 3 | 132
Multiple Sclerosis 3 | 498
Multiple myeloma 3 | 1,327
Neoplasm Metastasis 3 | 138
Pancreatic Neoplasm 3 | 79
Papilloma 3 | 27
Squamous cell carcinoma of esophagus 3 | 82
Stomach Neoplasms 3 | 282
Vascular disease 3 | 281
acute myeloid leukemia 3 | 780
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
dermatomyositis 3 | 933
ependymoma 3 | 2,514
gastric cancer 3 | 430
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group B ependymoma 3 | 1,530
Allergic hypersensitivity disease 2 | 123
Atherosclerosis 2 | 275
Cholestasis 2 | 93
Cockayne syndrome 2 | 54
Colonic Neoplasms 2 | 126
Dermatitis 2 | 107
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
Hepatitis B 2 | 103
Hypersensitivity reaction type II disease 2 | 235
Hypertensive disease 2 | 193
Liver carcinoma 2 | 217
Peripheral Neuropathy 2 | 303
Urticaria 2 | 53
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 532
nephrosclerosis 2 | 329
pancreatic carcinoma 2 | 567
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 31 | 17,995
Cardiovascular System 31 | 17,958
Digestive Tract 31 | 18,473
Endocrine System 31 | 18,512
Female tissues 31 | 18,647
Liver and Pancreas 31 | 18,136
Male tissues 31 | 17,969
Nervous System 31 | 18,561
Respiratory system 31 | 17,484
Skin and soft tissues 31 | 18,115
Urinary Tract 31 | 18,444

Target Family

Non-IDG 20 | 11,971
Enzyme 5 | 4,146
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

cellular response to ionizing ... 31 | 31
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177
Circadian locomoter output cycles protein kaput CLOCK Tbio TF/Epigenetic -2.56167 348.8 312
Growth arrest and DNA damage-inducible protein GADD45 alpha GADD45A Tbio Non-IDG -2.57552 356.6 214
Lysine-specific demethylase 4D KDM4D Tchem Epigenetic -1.39132 22.4 128
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.05859 1.38 29
Integrator complex subunit 7 INTS7 Tdark Non-IDG -0.79239 6.29 35
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -4.32707 20956.6 961
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.19692 1564.7 495
Elongation factor 1-delta EEF1D Tbio Non-IDG -1.46339 28.5 180