Development Level

Tbio 13 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal clavicle morphology 1 | 6
abnormal gait 1 | 69
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired righting response 1 | 26
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 13 | 8,520
Cancer 8 | 2,499
Carcinoma 8 | 11,493
lung cancer 8 | 4,740
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
Multiple myeloma 6 | 1,332
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
Arthritis 4 | 290
Asthma 4 | 385
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Encephalitis 4 | 64
Hypersensitivity reaction type II disease 4 | 253
Influenza 4 | 142
Kidney cancer 4 | 2,613
Vascular disease 4 | 319
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
subependymal giant cell astrocytoma 4 | 2,287
Hepatitis B 3 | 108
Hepatitis C 3 | 94
Lung disease 3 | 142
Microphthalmia with limb anomalies 3 | 40
Multiple Sclerosis 3 | 540
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
primary Sjogren syndrome 3 | 735
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Carcinoma, Hepatocellular 2 | 228
Dermatitis 2 | 157
Hepatitis 2 | 67
Herpes encephalitis 2 | 6
Herpes simplex 2 | 18
Human immunodeficiency virus infectious disease 2 | 138
Inflammatory bowel disease 2 | 151
Leigh disease 2 | 100
Liver carcinoma 2 | 240
Myocarditis 2 | 18
Neuromyelitis optica 2 | 18
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Rheumatoid arthritis 2 | 1,191
Severe acute respiratory syndrome 2 | 27
Thyroiditis 2 | 29
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
sarcoidosis 2 | 370
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Age related macular degeneration 1 | 72
Anogenital venereal wart 1 | 14
Arthritis, Experimental 1 | 39
Autosomal dominant Robinow syndrome 1 1 | 15
Brain Diseases 1 | 24
Bronchiectasis 1 | 64
Delayed Puberty 1 | 97
Dengue disease 1 | 23
Herpes zoster 1 | 68
Hypertension, Renovascular 1 | 10
Lyme disease 1 | 26
Neoplasm of stomach 1 | 11
Papillary thyroid carcinoma 1 | 43
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Progressive multifocal leukoencephalopathy 1 | 25
Renal Artery Stenosis 1 | 9
Skin disease 1 | 66
Stiff-Person syndrome 1 | 12
Tetanus 1 | 68
Tularemia 1 | 23

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725

Target Family

Non-IDG 8 | 12,091
Enzyme 5 | 4,145
Transcription Factor 2 | 1,400

GO Process

cellular response to interfero... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Interferon-inducible protein AIM2 AIM2 Tbio Non-IDG -2.17906 165.7 439
Ubiquitin-conjugating enzyme E2 G2 UBE2G2 Tbio Non-IDG -1.20607 15.4 270
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
Cis-aconitate decarboxylase ACOD1 Tbio Enzyme -1.79277 60.2 53
Tripartite motif-containing protein 6 TRIM6 Tbio Non-IDG 0.60 0.75 86
Probable ATP-dependent RNA helicase DDX41 DDX41 Tbio Enzyme -3.62934 3930.0 230
Stimulator of interferon genes protein TMEM173 Tbio Non-IDG -2.37722 230.3 450
Ubiquitin-conjugating enzyme E2 R1 CDC34 Tbio Non-IDG -2.08773 125.8 222
Ubiquitin-conjugating enzyme E2 K UBE2K Tbio Non-IDG -2.27406 139.4 327