Development Level

Tbio 44 | 11,445
Tchem 21 | 1,598
Tclin 14 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
decreased body weight 3 | 161
decreased vertical activity 3 | 208
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
increased circulating triglyce... 2 | 42
increased mean corpuscular vol... 2 | 92
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glycerol... 1 | 16
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 60 | 11,493
ovarian cancer 47 | 8,520
psoriasis 43 | 6,694
medulloblastoma, large-cell 38 | 6,241
osteosarcoma 38 | 7,950
Cancer 34 | 2,499
lung cancer 34 | 4,740
glioblastoma 33 | 5,792
diabetes mellitus 31 | 1,728
atypical teratoid / rhabdoid tumor 29 | 5,112
invasive ductal carcinoma 29 | 2,951
ependymoma 26 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
lung adenocarcinoma 24 | 2,716
non-small cell lung cancer 24 | 2,890
Obesity 23 | 678
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
Breast cancer 21 | 3,578
breast carcinoma 21 | 1,638
group 3 medulloblastoma 21 | 4,104
malignant mesothelioma 20 | 3,232
oligodendroglioma 20 | 2,850
Kidney cancer 19 | 2,613
Autosomal recessive predisposition 18 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
astrocytic glioma 17 | 2,597
lung carcinoma 17 | 2,843
pituitary cancer 17 | 1,972
Astrocytoma, Pilocytic 16 | 3,081
Hyperglycemia 16 | 137
ductal carcinoma in situ 16 | 1,745
Pick disease 15 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
Polycystic ovary syndrome 14 | 360
Schizophrenia 14 | 1,160
acute quadriplegic myopathy 14 | 1,158
adrenocortical carcinoma 14 | 1,428
pancreatic cancer 14 | 2,398
Liver Cirrhosis, Experimental 13 | 769
colon cancer 13 | 1,478
primitive neuroectodermal tumor 13 | 3,035
subependymal giant cell astrocytoma 13 | 2,287
Bipolar Disorder 12 | 666
Hyperinsulinism 12 | 133
Insulin Resistance 12 | 72
Diabetes Mellitus, Non-Insulin-Dependent 11 | 145
Fatty liver disease 11 | 103
Hypertension 11 | 396
interstitial cystitis 11 | 2,312
Diabetes Mellitus, Experimental 10 | 108
Diabetes Mellitus, Type 2 10 | 142
Lipid metabolism disorder 10 | 114
Rheumatoid arthritis 10 | 1,191
cystic fibrosis 10 | 1,696
dermatomyositis 10 | 966
Alzheimer's disease 9 | 658
Atherosclerosis 9 | 291
Breast Neoplasms 9 | 445
Intellectual disability 9 | 1,016
Mammary Neoplasms 9 | 425
Multiple myeloma 9 | 1,332
juvenile dermatomyositis 9 | 1,187
Carcinoma, Hepatocellular 8 | 228
Cerebrovascular disease 8 | 238
Coronary artery disease 8 | 268
Diabetes Mellitus, Noninsulin-Dependent 8 | 31
Heart disease 8 | 306
Liver carcinoma 8 | 240
Prostatic Neoplasms 8 | 495
astrocytoma 8 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
fibroadenoma 8 | 559
group 4 medulloblastoma 8 | 1,855
primary pancreatic ductal adenocarcinoma 8 | 1,109
Arthritis 7 | 290
Atopic dermatitis 7 | 952
Cognitive delay 7 | 608
Depressive disorder 7 | 409
Duchenne muscular dystrophy 7 | 601
Epilepsy 7 | 792
Global developmental delay 7 | 608
Hypertensive disease 7 | 292
Mental and motor retardation 7 | 608
Parkinson's disease 7 | 392
Seizures 7 | 596
active ulcerative colitis 7 | 764
cutaneous lupus erythematosus 7 | 1,057
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
Asthma 6 | 385
Chronic Lymphocytic Leukemia 6 | 262
Endometriosis 6 | 540
Kidney disease 6 | 430
Mental Depression 6 | 333
Vascular disease 6 | 319
active Crohn's disease 6 | 922
mucosa-associated lymphoid tissue lymphoma 6 | 484

Tissue

Digestive Tract 78 | 17,369
Endocrine System 78 | 18,159
Liver and Pancreas 77 | 16,750
Urinary Tract 77 | 16,678
Blood and immune system 76 | 16,909
Male tissues 76 | 17,142
Nervous System 76 | 16,725
Skin and soft tissues 76 | 17,230
Female tissues 75 | 17,400
Respiratory system 75 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 22 | 4,145
Kinase 18 | 634
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Transporter 3 | 473
GPCR 2 | 408
Nuclear Receptor 1 | 48

GO Process

cellular response to insulin s... 79 | 79
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Solute carrier family 25 member 33 SLC25A33 Tbio Transporter -0.33020 1.54 45
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG -0.04792 1.71 33
Sorbin and SH3 domain-containing protein 1 SORBS1 Tbio Non-IDG -1.57341 40.2 224
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.86682 77.3 148