Development Level

Tbio 46 | 10,625
Tchem 37 | 1,890
Tclin 12 | 602

IMPC Term

preweaning lethality, incomple... 5 | 260
decreased rib number 4 | 59
abnormal behavior 3 | 226
decreased bone mineral density 3 | 126
decreased erythrocyte cell num... 3 | 43
hypoactivity 3 | 89
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
preweaning lethality, complete... 3 | 633
abnormal heart morphology 2 | 51
abnormal iris morphology 2 | 12
abnormal maxilla morphology 2 | 16
abnormal retinal pigmentation 2 | 61
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
decreased bone mineral content 2 | 157
decreased startle reflex 2 | 48
decreased total body fat amoun... 2 | 186
increased circulating total pr... 2 | 20
increased grip strength 2 | 83
increased heart weight 2 | 37
increased or absent threshold ... 2 | 128
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased effector memory CD8-... 1 | 24
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased threshold for audito... 1 | 32
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased kidney weight 1 | 4
increased monocyte cell number 1 | 27
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
male infertility 1 | 62
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64
prolonged QRS complex duration 1 | 2
rib fusion 1 | 2
short tibia 1 | 82
small testis 1 | 37
thrombocytopenia 1 | 46
urinary bladder obstruction 1 | 2
vertebral fusion 1 | 23

Disease

ovarian cancer 59 | 8,484
Cancer 54 | 2,346
osteosarcoma 51 | 7,933
psoriasis 50 | 6,685
lung cancer 46 | 4,466
medulloblastoma, large-cell 46 | 6,234
glioblastoma 43 | 5,572
malignant mesothelioma 36 | 3,162
atypical teratoid / rhabdoid tumor 35 | 4,369
non-small cell lung cancer 30 | 2,798
Breast cancer 29 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
invasive ductal carcinoma 28 | 2,950
lung adenocarcinoma 28 | 2,713
primitive neuroectodermal tumor 28 | 3,031
pancreatic cancer 27 | 2,300
diabetes mellitus 26 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
ulcerative colitis 25 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
pediatric high grade glioma 23 | 2,712
colon cancer 22 | 1,475
cystic fibrosis 22 | 1,665
ductal carcinoma in situ 22 | 1,745
pituitary cancer 22 | 1,972
pilocytic astrocytoma 20 | 3,086
adrenocortical carcinoma 19 | 1,427
Mammary Neoplasms 18 | 410
Obesity 18 | 616
Prostatic Neoplasms 18 | 471
acute quadriplegic myopathy 18 | 1,157
astrocytic glioma 18 | 2,241
breast carcinoma 18 | 1,614
lung carcinoma 18 | 2,844
oligodendroglioma 18 | 2,849
Kidney disease 16 | 396
interstitial cystitis 16 | 2,299
sonic hedgehog group medulloblastoma 16 | 1,482
Alzheimer's disease 15 | 644
ependymoma 15 | 2,514
primary pancreatic ductal adenocarcinoma 15 | 1,271
subependymal giant cell astrocytoma 15 | 2,287
Diabetes Mellitus, Experimental 14 | 106
adult high grade glioma 14 | 2,148
medulloblastoma 14 | 1,524
Carcinoma 13 | 2,147
Endometriosis 13 | 535
group 4 medulloblastoma 13 | 1,875
posterior fossa group A ependymoma 13 | 1,511
tuberculosis 13 | 1,557
Hyperglycemia 12 | 120
Vascular disease 12 | 281
nasopharyngeal carcinoma 12 | 1,056
Amyotrophic Lateral Sclerosis 11 | 431
Asthma 11 | 349
Heart disease 11 | 279
Hypertensive disease 11 | 193
Peripheral Neuropathy 11 | 303
astrocytoma 11 | 1,493
atypical teratoid/rhabdoid tumor 11 | 1,095
gastric carcinoma 11 | 832
group 3 medulloblastoma 11 | 2,254
non-small cell lung carcinoma 11 | 413
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Hypertension 10 | 287
Metabolic syndrome X 10 | 155
Parkinson's disease 10 | 364
Renal Cell Carcinoma 10 | 199
esophageal adenocarcinoma 10 | 737
juvenile dermatomyositis 10 | 1,189
Adenoma 9 | 165
Atopic dermatitis 9 | 944
Lung Neoplasms 9 | 171
Schizophrenia 9 | 501
cutaneous lupus erythematosus 9 | 1,056
Cerebrovascular disease 8 | 231
Diabetes Mellitus, Non-Insulin-Dependent 8 | 157
Lung disease 8 | 132
Melanoma 8 | 261
Multiple myeloma 8 | 1,327
Myocardial Infarction 8 | 126
Myocardial Ischemia 8 | 169
Neurodegenerative disease 8 | 383
Pick disease 8 | 1,893
Reperfusion Injury 8 | 84
Stomach Neoplasms 8 | 282
dermatomyositis 8 | 933
non primary Sjogren syndrome sicca 8 | 840
spina bifida 8 | 1,064
Arthritis 7 | 248
Brain Ischemia 7 | 87
Cardiomyopathies 7 | 90
Coronary artery disease 7 | 240
Down syndrome 7 | 548
Inflammation 7 | 109
Liver Cirrhosis, Experimental 7 | 108
Liver carcinoma 7 | 217
Polycystic Ovary Syndrome 7 | 332
Rheumatoid Arthritis 7 | 1,160
active Crohn's disease 7 | 918

Tissue

Digestive Tract 95 | 18,473
Liver and Pancreas 95 | 18,136
Nervous System 95 | 18,561
Urinary Tract 95 | 18,444
Endocrine System 94 | 18,512
Female tissues 94 | 18,647
Skin and soft tissues 94 | 18,115
Blood and immune system 93 | 17,995
Male tissues 93 | 17,969
Respiratory system 93 | 17,484
Cardiovascular System 91 | 17,958

Target Family

Non-IDG 46 | 11,971
Enzyme 12 | 4,146
Kinase 9 | 634
Transcription Factor 8 | 1,400
Epigenetic 6 | 242
Ion Channel 6 | 341
Transporter 5 | 473
Nuclear Receptor 2 | 48
GPCR 1 | 406

GO Process

cellular response to hypoxia 95 | 95
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Nuclear receptor ROR-alpha RORA Tchem Nuclear Receptor -2.17386 139.2 340
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.43974 36.3 260
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144
Stanniocalcin-2 STC2 Tbio Non-IDG -1.72873 62.1 298