Development Level

Tbio 33 | 11,445
Tchem 21 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal seminal vesicle morph... 3 | 114
abnormal embryo size 2 | 220
decreased grip strength 2 | 116
decreased large unstained cell... 2 | 11
embryonic lethality prior to t... 2 | 278
male infertility 2 | 123
small testis 2 | 58
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
small superior vagus ganglion 1 | 74
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Cancer 41 | 2,499
Carcinoma 39 | 11,493
lung cancer 38 | 4,740
ovarian cancer 38 | 8,520
osteosarcoma 34 | 7,950
psoriasis 30 | 6,694
medulloblastoma, large-cell 29 | 6,241
glioblastoma 28 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
ependymoma 23 | 4,679
lung adenocarcinoma 21 | 2,716
non-small cell lung cancer 21 | 2,890
group 3 medulloblastoma 20 | 4,104
pancreatic cancer 20 | 2,398
malignant mesothelioma 19 | 3,232
primitive neuroectodermal tumor 19 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Breast cancer 16 | 3,578
astrocytoma 16 | 1,146
oligodendroglioma 16 | 2,850
tuberculosis 16 | 2,010
ulcerative colitis 16 | 1,819
diabetes mellitus 15 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
adult high grade glioma 14 | 3,801
Liver Cirrhosis, Experimental 12 | 769
adrenocortical carcinoma 12 | 1,428
breast carcinoma 12 | 1,638
invasive ductal carcinoma 12 | 2,951
Vascular disease 11 | 319
interstitial cystitis 11 | 2,312
juvenile dermatomyositis 11 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
subependymal giant cell astrocytoma 11 | 2,287
Astrocytoma, Pilocytic 10 | 3,081
Autosomal recessive predisposition 10 | 1,442
Kidney disease 10 | 430
Prostatic Neoplasms 10 | 495
ductal carcinoma in situ 10 | 1,745
pituitary cancer 10 | 1,972
Kidney cancer 9 | 2,613
Melanoma 9 | 711
Multiple myeloma 9 | 1,332
Neurodegenerative disease 9 | 414
Rheumatoid arthritis 9 | 1,191
colon cancer 9 | 1,478
primary pancreatic ductal adenocarcinoma 9 | 1,109
Alzheimer's disease 8 | 658
Endometriosis 8 | 540
Obesity 8 | 678
acute quadriplegic myopathy 8 | 1,158
group 4 medulloblastoma 8 | 1,855
nasopharyngeal carcinoma 8 | 1,058
pancreatic carcinoma 8 | 562
primary Sjogren syndrome 8 | 735
Atopic dermatitis 7 | 952
Breast Neoplasms 7 | 445
Down syndrome 7 | 499
Hypertension 7 | 396
Mammary Neoplasms 7 | 425
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
dermatomyositis 7 | 966
Atherosclerosis 6 | 291
Chemical and Drug Induced Liver Injury 6 | 195
Diabetes Mellitus, Experimental 6 | 108
Heart disease 6 | 306
Hypertensive disease 6 | 292
Intellectual disability 6 | 1,016
Pick disease 6 | 1,894
Seizures 6 | 596
astrocytic glioma 6 | 2,597
chronic rhinosinusitis 6 | 512
cystic fibrosis 6 | 1,696
gastric cancer 6 | 459
gastric carcinoma 6 | 807
spina bifida 6 | 1,074
Acute kidney injury 5 | 70
Asthma 5 | 385
Bipolar Disorder 5 | 666
Carcinoma, Squamous Cell 5 | 110
Chronic obstructive pulmonary disease 5 | 184
Congenital pes cavus 5 | 88
Hyperglycemia 5 | 137
Neoplasm Metastasis 5 | 168
Neuropathy 5 | 261
Squamous cell carcinoma 5 | 129
Toxic encephalopathy 5 | 141
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559
mucosa-associated lymphoid tissue lymphoma 5 | 484
Mental Depression 4 | 333
hepatocellular carcinoma 4 | 547

Tissue

Endocrine System 60 | 18,159
Female tissues 60 | 17,400
Nervous System 60 | 16,725
Urinary Tract 60 | 16,678
Blood and immune system 59 | 16,909
Digestive Tract 59 | 17,369
Liver and Pancreas 59 | 16,750
Male tissues 59 | 17,142
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 24 | 12,091
Transcription Factor 11 | 1,400
Enzyme 10 | 4,145
Kinase 7 | 634
Epigenetic 6 | 242
Ion Channel 2 | 344

GO Process

cellular response to hydrogen ... 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Interleukin-18-binding protein IL18BP Tbio Non-IDG -2.00596 101.6 307
Zinc finger protein 580 ZNF580 Tbio Transcription Factor -1.04597 11.4 74
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.22888 174.2 272
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866