Development Level

Tbio 16 | 11,445
Tchem 14 | 1,598
Tclin 13 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328

IMPC Phenotype

decreased total body fat amoun... 4 | 207
abnormal behavior 3 | 298
hyperactivity 3 | 148
increased lean body mass 3 | 172
decreased body weight 2 | 161
decreased fasted circulating g... 2 | 65
decreased vertical activity 2 | 208
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased kidney weight 1 | 6
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 32 | 11,493
psoriasis 25 | 6,694
glioblastoma 23 | 5,792
ovarian cancer 23 | 8,520
Cancer 21 | 2,499
lung cancer 20 | 4,740
medulloblastoma, large-cell 17 | 6,241
lung carcinoma 16 | 2,843
non-small cell lung cancer 15 | 2,890
osteosarcoma 15 | 7,950
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 14 | 4,679
lung adenocarcinoma 14 | 2,716
malignant mesothelioma 14 | 3,232
Astrocytoma, Pilocytic 13 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
adrenocortical carcinoma 12 | 1,428
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
invasive ductal carcinoma 12 | 2,951
Kidney cancer 11 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pituitary cancer 11 | 1,972
Schizophrenia 10 | 1,160
group 4 medulloblastoma 10 | 1,855
Liver Cirrhosis, Experimental 9 | 769
astrocytoma 9 | 1,146
breast carcinoma 9 | 1,638
group 3 medulloblastoma 9 | 4,104
oligodendroglioma 9 | 2,850
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Epilepsy 8 | 792
Obesity 8 | 678
Prostatic Neoplasms 8 | 495
aldosterone-producing adenoma 8 | 665
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
ductal carcinoma in situ 8 | 1,745
fibroadenoma 8 | 559
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primitive neuroectodermal tumor 8 | 3,035
Autosomal recessive predisposition 7 | 1,442
Breast Neoplasms 7 | 445
Hypertension 7 | 396
Mammary Neoplasms 7 | 425
astrocytic glioma 7 | 2,597
Arthritis, Juvenile 6 | 126
Depressive disorder 6 | 409
Juvenile arthritis 6 | 126
Kidney disease 6 | 430
Lung Neoplasms 6 | 232
Rheumatoid arthritis 6 | 1,191
gastric cancer 6 | 459
interstitial cystitis 6 | 2,312
Arthritis 5 | 290
Atopic dermatitis 5 | 952
Autistic Disorder 5 | 364
Hypertensive disease 5 | 292
Mental Depression 5 | 333
Multiple myeloma 5 | 1,332
Pain agnosia 5 | 104
Parkinson's disease 5 | 392
Status Epilepticus 5 | 98
Waldenstrons macroglobulinemia 5 | 765
chronic lymphosyte leukemia 5 | 204
nephrosclerosis 5 | 333
pterygium 5 | 76
tuberculosis 5 | 2,010
Asthma 4 | 385
Cocaine-Related Disorders 4 | 92
Congenital adrenal hyperplasia 4 | 73
Down syndrome 4 | 499
Eye disease 4 | 62
Heart disease 4 | 306
Intellectual disability 4 | 1,016
Liver neoplasms 4 | 130
Major Depressive Disorder 4 | 301
Melanoma 4 | 711
Mood Disorders 4 | 184
Multiple Sclerosis 4 | 540
Narcolepsy 4 | 72
Seizures 4 | 596
Short stature 4 | 531
Unipolar Depression 4 | 250
Vascular disease 4 | 319
acute myeloid leukemia 4 | 783
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung carcinoma 4 | 317
pancreatic carcinoma 4 | 562
subependymal giant cell astrocytoma 4 | 2,287
urothelial carcinoma 4 | 318
Anorexia nervosa 3 | 80
Bipolar Disorder 3 | 666
Pick disease 3 | 1,894
dermatomyositis 3 | 966
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 44 | 18,159
Digestive Tract 41 | 17,369
Urinary Tract 41 | 16,678
Female tissues 40 | 17,400
Nervous System 40 | 16,725
Male tissues 39 | 17,142
Liver and Pancreas 38 | 16,750
Skin and soft tissues 38 | 17,230
Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Respiratory system 36 | 16,393

Target Family

Non-IDG 14 | 12,091
GPCR 12 | 408
Transcription Factor 7 | 1,400
Enzyme 5 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

cellular response to hormone s... 44 | 44
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Orexin receptor type 1 HCRTR1 Tclin GPCR -2.20503 162.0 294
Cytochrome P450 11B1, mitochondrial CYP11B1 Tclin Enzyme -2.66308 432.9 136
Asparagine synthetase [glutamine-hydrolyzing] ASNS Tchem Enzyme -2.40144 244.3 223
Cytochrome P450 11B2, mitochondrial CYP11B2 Tchem Non-IDG -2.82678 695.9 162
Alpha-2A adrenergic receptor ADRA2A Tclin GPCR -2.42160 261.4 232
Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H Tclin Ion Channel -2.10494 132.8 190
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630