Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
absent seminal vesicle 1 | 4
decreased body length 1 | 101
decreased body weight 1 | 161
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
increased cardiac muscle contr... 1 | 8
increased circulating glucose ... 1 | 24
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small uterus 1 | 3

Disease

Carcinoma 5 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
ovarian cancer 5 | 8,520
Cancer 4 | 2,499
colon cancer 4 | 1,478
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
pancreatic cancer 4 | 2,398
Breast cancer 3 | 3,578
Down syndrome 3 | 499
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Atopic dermatitis 2 | 952
Hydronephrosis 2 | 89
Lung Neoplasms 2 | 232
Pick disease 2 | 1,894
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
11 pairs of ribs 1 | 7
46 XY gonadal dysgenesis 1 | 10
ANONYCHIA 1 | 20
Abnormality of the pharynx 1 | 19
Absent bone maturation in sternum 1 | 4
Absent sternal ossification 1 | 4
Ambiguous Genitalia 1 | 24
Anonychia congenita 1 | 2
Autism Spectrum Disorders 1 | 75
Bipolar I disorder 1 | 23
Cholangitis 1 | 32
Decreased fertility 1 | 33
Decreased fertility in females 1 | 20
Decreased testosterone in males 1 | 28
Delayed Puberty 1 | 97
Elevated follicle stimulating hormone 1 | 15
Epilepsy, Temporal Lobe 1 | 23
Female external genitalia in males 1 | 13
Femoral bowing 1 | 20
Fibroid Tumor 1 | 6
Glossoptosis 1 | 10
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Gynecomastia 1 | 64
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplasia of scrotum 1 | 24
Hypoplasia of vagina 1 | 14
Hypospadias 1 | 53
Inflammatory Bowel Diseases 1 | 35
Intrahepatic cholestasis 1 | 20
Ischemia 1 | 28
Kyphoscoliosis deformity of spine 1 | 60
Laryngomalacia 1 | 14
Leiomyoma 1 | 32
Low serum estradiol levels 1 | 22
Male Pseudohermaphroditism 1 | 19
Posterior displacement of the tongue 1 | 10
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Pure gonadal dysgenesis 1 | 19
Respiratory Distress Syndrome 1 | 15
Rudimentary vagina 1 | 14
Sclerocystic Ovaries 1 | 17
Sex reversal 1 | 10
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Small face 1 | 10
Small testicle 1 | 75
Sparse axillary hair 1 | 28
Sparse pubic hair 1 | 31
Streak ovary 1 | 15
Swyer Syndrome 1 | 8
Testicular dysgenesis 1 | 9
Testicular hypogonadism 1 | 21
Testicular regression syndrome 1 | 9
Urogenital sinus anomaly 1 | 15
Vesicoureteral reflux 1 | 32
West Nile encephalitis 1 | 9

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

cellular response to heparin 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Amiloride-sensitive amine oxidase [copper-containing] AOC1 Tchem Enzyme -2.77629 590.0 271
Slit homolog 2 protein SLIT2 Tbio Non-IDG -2.01765 104.0 215
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.40092 279.5 264
Early growth response protein 1 EGR1 Tbio Transcription Factor -3.29817 2034.6 394