Development Level

Tbio 27 | 11,445
Tchem 11 | 1,598
Tclin 7 | 613

IMPC Phenotype

abnormal eye morphology 2 | 68
decreased body weight 2 | 161
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
corneal opacity 1 | 32
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating glucose ... 1 | 24
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 31 | 11,493
ovarian cancer 29 | 8,520
Cancer 28 | 2,499
glioblastoma 26 | 5,792
psoriasis 22 | 6,694
atypical teratoid / rhabdoid tumor 20 | 5,112
lung cancer 20 | 4,740
medulloblastoma, large-cell 20 | 6,241
ependymoma 17 | 4,679
osteosarcoma 17 | 7,950
Breast cancer 16 | 3,578
group 3 medulloblastoma 14 | 4,104
invasive ductal carcinoma 14 | 2,951
Astrocytoma, Pilocytic 13 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
adrenocortical carcinoma 12 | 1,428
primitive neuroectodermal tumor 12 | 3,035
diabetes mellitus 11 | 1,728
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
pancreatic cancer 11 | 2,398
subependymal giant cell astrocytoma 11 | 2,287
tuberculosis 11 | 2,010
acute quadriplegic myopathy 10 | 1,158
adult high grade glioma 10 | 3,801
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
pituitary cancer 10 | 1,972
Depressive disorder 9 | 409
Multiple myeloma 9 | 1,332
Schizophrenia 9 | 1,160
ductal carcinoma in situ 9 | 1,745
group 4 medulloblastoma 9 | 1,855
Alcoholic Intoxication, Chronic 7 | 289
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Kidney disease 7 | 430
Mammary Neoplasms 7 | 425
Obesity 7 | 678
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
interstitial cystitis 7 | 2,312
oligodendroglioma 7 | 2,850
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
Autosomal recessive predisposition 6 | 1,442
Nerve Degeneration 6 | 121
Prostatic Neoplasms 6 | 495
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
esophageal adenocarcinoma 6 | 737
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
Down syndrome 5 | 499
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Neoplasm Metastasis 5 | 168
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Unipolar Depression 5 | 250
Vascular disease 5 | 319
cystic fibrosis 5 | 1,696
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer's disease 4 | 658
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Blepharoptosis 4 | 231
Colonic Neoplasms 4 | 142
Diarrhea 4 | 253
Hyperalgesia 4 | 83
Hypertension 4 | 396
Liver Cirrhosis 4 | 181
Liver Cirrhosis, Experimental 4 | 769
Multiple, subcutaneous nodules 4 | 53
Neoplasm Invasiveness 4 | 161
Osteoporosis 4 | 363
Ovarian Neoplasms 4 | 102
Parkinsonian Disorders 4 | 56
Psychotic Disorders 4 | 151
Rheumatoid arthritis 4 | 1,191
Subcutaneous nodule 4 | 53
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
cutaneous lupus erythematosus 4 | 1,057
fibroadenoma 4 | 559
gastric cancer 4 | 459
medulloblastoma 4 | 720
ovarian neoplasm 4 | 99
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Polycystic ovary syndrome 3 | 360
Waldenstrons macroglobulinemia 3 | 765
spina bifida 3 | 1,074

Tissue

Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Blood and immune system 43 | 16,909
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Liver and Pancreas 41 | 16,750
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 9 | 4,145
Kinase 8 | 634
Transcription Factor 6 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

cellular response to growth fa... 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive serine/threonine-protein kinase PLK5 PLK5 Tbio Kinase -0.60609 4.07 119
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Emerin EMD Tbio Non-IDG -2.80459 640.6 299
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Copine-3 CPNE3 Tbio Non-IDG -0.95488 10.4 119
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Profilin-1 PFN1 Tbio Non-IDG -2.31736 223.5 260
Low-density lipoprotein receptor-related protein 8 LRP8 Tbio Non-IDG -2.17223 148.7 283