Development Level

Tbio 15 | 11,445
Tchem 12 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased circulating insulin ... 3 | 76
embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent seminal vesicle 1 | 4
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small seminal vesicle 1 | 10
small spleen 1 | 19
small testis 1 | 58
small uterus 1 | 3
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 20 | 11,493
ovarian cancer 20 | 8,520
Cancer 19 | 2,499
medulloblastoma, large-cell 16 | 6,241
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
osteosarcoma 15 | 7,950
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 11 | 5,112
psoriasis 11 | 6,694
breast carcinoma 10 | 1,638
Breast Neoplasms 8 | 445
Prostatic Neoplasms 8 | 495
acute quadriplegic myopathy 8 | 1,158
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
Colonic Neoplasms 7 | 142
Mammary Neoplasms 7 | 425
Nijmegen breakage syndrome 7 | 24
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Ataxia telangiectasia 6 | 34
Autosomal recessive predisposition 6 | 1,442
Lung Neoplasms 6 | 232
Short stature 6 | 531
Stomach Neoplasms 6 | 300
Werner syndrome 6 | 29
Xeroderma pigmentosum 6 | 43
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
Carcinoma, Hepatocellular 5 | 228
Kidney cancer 5 | 2,613
Liver carcinoma 5 | 240
Multiple myeloma 5 | 1,332
Myocardial Infarction 5 | 151
Pancreatic Neoplasm 5 | 85
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
pituitary cancer 5 | 1,972
Adenoma 4 | 167
Astrocytoma, Pilocytic 4 | 3,081
Bladder Neoplasm 4 | 112
Carcinoma, Squamous Cell 4 | 110
Cockayne syndrome 4 | 60
Dull intelligence 4 | 645
Epilepsy 4 | 792
Fanconi anemia 4 | 56
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Seizures 4 | 596
Skin Neoplasms 4 | 69
Squamous cell carcinoma 4 | 129
Urinary Bladder Neoplasms 4 | 114
Vascular disease 4 | 319
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non-small cell lung carcinoma 4 | 317
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Adenoid Cystic Carcinoma 3 | 99
Anemia 3 | 365
Carcinoma, Adenoid Cystic 3 | 99
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Disease Progression 3 | 136
Endometriosis 3 | 540
Heart disease 3 | 306
Hypertension 3 | 396
Mouth Neoplasms 3 | 55
Multiple Sclerosis 3 | 540
Neuroblastoma 3 | 80
Neurodegenerative disease 3 | 414
Pancreatic Neoplasms 3 | 85
Pick disease 3 | 1,894
Strabismus 3 | 270
Toxic encephalopathy 3 | 141
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242

GO Process

cellular response to gamma rad... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Testis-specific Y-encoded-like protein 5 TSPYL5 Tbio Non-IDG -0.97896 9.36 76
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
60S ribosomal protein L26 RPL26 Tbio Non-IDG -1.66446 44.8 126
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Transmembrane protein 109 TMEM109 Tbio Non-IDG -0.59060 3.93 38
ETS domain-containing protein Elk-1 ELK1 Tbio Transcription Factor -0.51976 3.02 941
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Serine/threonine-protein kinase tousled-like 2 TLK2 Tchem Kinase -0.95456 10.1 210
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298