Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cataract 1 | 92
decreased bone mineral content 1 | 151
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979

Disease

psoriasis 10 | 6,694
ovarian cancer 9 | 8,520
Carcinoma 8 | 11,493
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
astrocytic glioma 5 | 2,597
glioblastoma 5 | 5,792
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
atypical teratoid / rhabdoid tumor 4 | 5,112
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Alzheimer's disease 3 | 658
Myocardial Infarction 3 | 151
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Abnormality of metabolism/homeostasis 2 | 134
Adrenogenital Syndrome 2 | 6
Amenorrhea 2 | 58
Ancylostomiasis 2 | 6
Anovulation 2 | 21
Cell Transformation, Neoplastic 2 | 97
Congenital adrenal hyperplasia 2 | 73
Delayed Puberty 2 | 97
Delayed bone age 2 | 136
Enlarged polycystic ovaries 2 | 10
Hydrocephalus 2 | 152
Hyperandrogenism 2 | 34
Hypertension 2 | 396
Hypogonadism 2 | 173
Increased serum testosterone level 2 | 4
Increased testosterone 2 | 4
Infertility 2 | 188
Low serum estradiol levels 2 | 22
Lymphoid leukemia 2 | 160
Neoplastic Cell Transformation 2 | 89
Osteoporosis 2 | 363
Penile hypospadias 2 | 106
Toxic encephalopathy 2 | 141
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
ulcerative colitis 2 | 1,819
Abnormal sex determination 1 | 11
Amino Acid Metabolism, Inborn Errors 1 | 13
Bifid scrotum 1 | 16
Bronchomalacia 1 | 7
Calvarial defect 1 | 10
Chordee 1 | 6
Chronic phase chronic myeloid leukemia 1 | 45
Cranial defect 1 | 10
Decreased fertility in females 1 | 20
Decreased male fertility 1 | 7
Deficiency of testosterone biosynthesis 1 | 6
Ectopic adrenal gland 1 | 2
Female external genitalia in males 1 | 13
Femoral bowing 1 | 20
Fused labia minora 1 | 5
Hemorrhagic cyst of ovary 1 | 2
Hypoplasia of vagina 1 | 14
Learning Disorders 1 | 29
Omenn syndrome 1 | 13
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Premature adrenarche 1 | 3
Rudimentary vagina 1 | 14
Skull defect 1 | 10
Small labia majora 1 | 16
Stenosis of external auditory canal 1 | 13
Urogenital sinus anomaly 1 | 15
Vesicovaginal Fistula 1 | 2

Tissue

Endocrine System 11 | 18,159
Liver and Pancreas 11 | 16,750
Nervous System 11 | 16,725
Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Urinary Tract 9 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408
Kinase 1 | 634

GO Process

cellular response to follicle-... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hydroxymethylglutaryl-CoA synthase, cytoplasmic HMGCS1 Tchem Enzyme -1.67608 43.7 137
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277
Glutamate--cysteine ligase catalytic subunit GCLC Tchem Enzyme -2.48963 294.6 293
Ephrin-A5 EFNA5 Tbio Non-IDG -2.57120 355.6 202
Follicle-stimulating hormone receptor FSHR Tclin GPCR -2.79144 610.7 386
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Inhibin beta A chain INHBA Tbio Non-IDG -1.92108 76.6 319
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PPARGC1A Tbio Non-IDG -2.86449 728.1 274