Development Level

Tbio 9 | 11,651
Tchem 3 | 1,388

IMPC Phenotype

abnormal pupil morphology 1 | 2
aorta stenosis 1 | 2
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
thin ventricular wall 1 | 24

Disease

Carcinoma 8 | 11,493
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
astrocytic glioma 5 | 2,597
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Epilepsy 4 | 792
Kidney cancer 4 | 2,613
Dull intelligence 3 | 645
Dysarthria 3 | 192
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Pick disease 3 | 1,894
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Seizures 3 | 596
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
Action Tremor 2 | 22
Alcoholic Intoxication, Chronic 2 | 289
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Cognitive delay 2 | 608
Congenital hypoplasia of penis 2 | 176
Decreased bone mineral density Z score 2 | 31
Depressive disorder 2 | 409
Difficulties with night vision 2 | 87
Dysdiadochokinesis 2 | 25
Fundus albipunctatus 2 | 10
Global developmental delay 2 | 608
Gynecomastia 2 | 64
Hypertension 2 | 396
Lens Opacities 2 | 231
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Myopathy 2 | 185
Myopia 2 | 176
Neurodegenerative disease 2 | 414
Night Blindness 2 | 101
Obesity 2 | 678
Reduced visual acuity 2 | 63
Reperfusion Injury 2 | 86
Retinitis Pigmentosa 2 | 226
Short stature 2 | 531
Slow progression 2 | 89
Tremor 2 | 113
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Abnormal lung lobation 1 | 10
Abnormality of macular pigmentation 1 | 16
Angioid streaks 1 | 11
Anosmia 1 | 22
Aqueductal Stenosis 1 | 5
Asymmetric chest 1 | 4
Birth length greater than 97th percentile 1 | 5
Calvarial hyperostosis 1 | 5
Enlarged cerebellum 1 | 3
Enlargement of calvarial bones 1 | 5
Exostoses 1 | 11
Gastrointestinal polyps 1 | 5
Heterochromia iridis 1 | 9
Increased ossification of calvarial bones 1 | 5
Intestinal Polyposis 1 | 6
Kallmann syndrome 1 | 33
Leber congenital amaurosis 2 1 | 4
Leg Length Inequality 1 | 6
Lipomatosis 1 | 12
Macular pigmentary changes 1 | 16
Meningioma, familial 1 | 6
Molluscum contagiosum 1 | 8
Multiple lipomata 1 | 7
NEVUS, EPIDERMAL (disorder) 1 | 5
Partial fetal alcohol syndrome 1 | 6
Pupillary abnormality 1 | 4
Sense of smell impaired 1 | 21
Severe myopia 1 | 22
Thyroid cancer, follicular 1 | 8

Tissue

Nervous System 12 | 16,725
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Liver and Pancreas 9 | 16,750
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Respiratory system 7 | 16,393

Target Family

Enzyme 4 | 4,145
Non-IDG 4 | 12,091
Transcription Factor 2 | 1,400
GPCR 1 | 408
Transporter 1 | 473

GO Process

cellular response to electrica... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NMDA receptor synaptonuclear signaling and neuronal migration factor NSMF Tbio Non-IDG -0.74299 6.02 122
Guanine nucleotide-binding protein G(t) subunit alpha-1 GNAT1 Tbio Non-IDG -1.41254 22.0 137
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tbio Enzyme -3.70874 5099.6 916
Neuron-specific calcium-binding protein hippocalcin HPCA Tbio Non-IDG -1.77196 62.9 80
Metabotropic glutamate receptor 1 GRM1 Tchem GPCR -3.05662 1115.6 490
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Paralemmin-1 PALM Tbio Non-IDG -1.24016 17.2 62
RE1-silencing transcription factor REST Tbio Transcription Factor -2.44426 245.2 178
Neurogenic differentiation factor 2 NEUROD2 Tbio Transcription Factor -1.61613 43.4 151
Adenylosuccinate synthetase isozyme 1 ADSSL1 Tbio Enzyme -0.86563 9.41 87