Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal pupil morphology 1 | 2
aorta stenosis 1 | 2
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
thin ventricular wall 1 | 24

Disease

Carcinoma 8 | 11,493
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
astrocytic glioma 5 | 2,597
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Epilepsy 4 | 792
Kidney cancer 4 | 2,613
Dull intelligence 3 | 645
Dysarthria 3 | 192
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Pick disease 3 | 1,894
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Seizures 3 | 596
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
Action Tremor 2 | 22
Alcoholic Intoxication, Chronic 2 | 289
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Cognitive delay 2 | 608
Congenital hypoplasia of penis 2 | 176
Decreased bone mineral density Z score 2 | 31
Depressive disorder 2 | 409
Difficulties with night vision 2 | 87
Dysdiadochokinesis 2 | 25
Fundus albipunctatus 2 | 10
Global developmental delay 2 | 608
Gynecomastia 2 | 64
Hypertension 2 | 396
Lens Opacities 2 | 231
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Myopathy 2 | 185
Myopia 2 | 176
Neurodegenerative disease 2 | 414
Night Blindness 2 | 101
Obesity 2 | 678
Reduced visual acuity 2 | 63
Reperfusion Injury 2 | 86
Retinitis Pigmentosa 2 | 226
Short stature 2 | 531
Slow progression 2 | 89
Tremor 2 | 113
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Abnormal lung lobation 1 | 10
Abnormality of macular pigmentation 1 | 16
Angioid streaks 1 | 11
Anosmia 1 | 22
Aqueductal Stenosis 1 | 5
Asymmetric chest 1 | 4
Birth length greater than 97th percentile 1 | 5
Calvarial hyperostosis 1 | 5
Enlarged cerebellum 1 | 3
Enlargement of calvarial bones 1 | 5
Exostoses 1 | 11
Gastrointestinal polyps 1 | 5
Heterochromia iridis 1 | 9
Increased ossification of calvarial bones 1 | 5
Intestinal Polyposis 1 | 6
Kallmann syndrome 1 | 33
Leber congenital amaurosis 2 1 | 4
Leg Length Inequality 1 | 6
Lipomatosis 1 | 12
Macular pigmentary changes 1 | 16
Meningioma, familial 1 | 6
Molluscum contagiosum 1 | 8
Multiple lipomata 1 | 7
NEVUS, EPIDERMAL (disorder) 1 | 5
Partial fetal alcohol syndrome 1 | 6
Pupillary abnormality 1 | 4
Sense of smell impaired 1 | 21
Severe myopia 1 | 22
Thyroid cancer, follicular 1 | 8

Tissue

Nervous System 12 | 16,725
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Liver and Pancreas 9 | 16,750
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Respiratory system 7 | 16,393

Target Family

Enzyme 4 | 4,145
Non-IDG 4 | 12,091
Transcription Factor 2 | 1,400
GPCR 1 | 408
Transporter 1 | 473

GO Process

cellular response to electrica... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Paralemmin-1 PALM Tbio Non-IDG -1.24016 17.2 62
Neuron-specific calcium-binding protein hippocalcin HPCA Tbio Non-IDG -1.77196 62.9 80
Metabotropic glutamate receptor 1 GRM1 Tchem GPCR -3.05662 1115.6 490
NMDA receptor synaptonuclear signaling and neuronal migration factor NSMF Tbio Non-IDG -0.74299 6.02 122
RE1-silencing transcription factor REST Tbio Transcription Factor -2.44426 245.2 178
Neurogenic differentiation factor 2 NEUROD2 Tbio Transcription Factor -1.61613 43.4 151
Adenylosuccinate synthetase isozyme 1 ADSSL1 Tbio Enzyme -0.86563 9.41 87
Adenylosuccinate synthetase isozyme 2 ADSS Tchem Enzyme -1.98255 95.0 107
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tchem Enzyme -3.70874 5099.6 916