Development Level

Tbio 33 | 11,178
Tclin 16 | 612
Tchem 15 | 1,885
Tdark 1 | 6,569

IMPC Phenotype

decreased vertical activity 4 | 208
increased lean body mass 4 | 172
preweaning lethality, complete... 4 | 979
decreased total body fat amoun... 3 | 207
decreased circulating glucose ... 2 | 126
decreased leukocyte cell numbe... 2 | 73
decreased mean platelet volume 2 | 25
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
aorta stenosis 1 | 2
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased circulating calcium ... 1 | 34
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 41 | 11,192
ovarian cancer 36 | 8,297
medulloblastoma, large-cell 30 | 6,086
glioblastoma 29 | 5,635
osteosarcoma 27 | 7,766
psoriasis 27 | 6,514
ependymoma 26 | 4,559
lung cancer 26 | 4,607
Cancer 25 | 2,388
atypical teratoid / rhabdoid tumor 24 | 4,971
adult high grade glioma 22 | 3,701
invasive ductal carcinoma 22 | 2,867
Breast cancer 21 | 3,469
lung adenocarcinoma 21 | 2,627
Astrocytoma, Pilocytic 20 | 3,006
lung carcinoma 20 | 2,755
group 3 medulloblastoma 19 | 4,002
non-small cell lung cancer 19 | 2,799
malignant mesothelioma 18 | 3,135
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,204
oligodendroglioma 17 | 2,768
diabetes mellitus 16 | 1,683
subependymal giant cell astrocytoma 16 | 2,230
astrocytic glioma 15 | 2,530
interstitial cystitis 15 | 2,237
tuberculosis 15 | 1,963
Autosomal recessive predisposition 14 | 1,407
Schizophrenia 13 | 1,136
adrenocortical carcinoma 13 | 1,385
Seizures 12 | 584
primitive neuroectodermal tumor 12 | 2,957
Carcinoma, Hepatocellular 11 | 217
Liver carcinoma 11 | 229
Prostatic Neoplasms 11 | 472
acute quadriplegic myopathy 11 | 1,133
aldosterone-producing adenoma 11 | 646
ulcerative colitis 11 | 1,765
Asthma 10 | 370
Bipolar Disorder 10 | 646
Epilepsy 10 | 775
breast carcinoma 10 | 1,589
cutaneous lupus erythematosus 10 | 1,016
cystic fibrosis 10 | 1,629
ductal carcinoma in situ 10 | 1,686
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,902
Colonic Neoplasms 9 | 133
Hypertension 9 | 372
Hypertensive disease 9 | 278
Kidney disease 9 | 411
Liver Cirrhosis, Experimental 9 | 733
Lung disease 9 | 135
Major Depressive Disorder 9 | 293
Multiple Sclerosis 9 | 527
Unipolar Depression 9 | 244
pituitary cancer 9 | 1,915
Alcoholic Intoxication, Chronic 8 | 283
Breast Neoplasms 8 | 423
Colorectal Neoplasms 8 | 235
Depressive disorder 8 | 401
Heart disease 8 | 288
Mammary Neoplasms 8 | 403
Mental Depression 8 | 325
Obesity 8 | 655
Rheumatoid arthritis 8 | 1,156
Stomach Neoplasms 8 | 287
pancreatic cancer 8 | 2,322
Alzheimer's disease 7 | 640
Arthritis 7 | 276
Atherosclerosis 7 | 276
Atopic dermatitis 7 | 915
Cardiomegaly 7 | 114
Cerebrovascular disease 7 | 223
Diabetes Mellitus, Type 2 7 | 136
Endometriosis 7 | 521
Hyperglycemia 7 | 134
Kidney cancer 7 | 2,548
Liver disease 7 | 227
Lung Neoplasms 7 | 217
Multiple myeloma 7 | 1,296
Muscle hypotonia 7 | 562
Myocardial Ischemia 7 | 162
Pick disease 7 | 1,856
Vascular disease 7 | 294
active Crohn's disease 7 | 882
colon cancer 7 | 1,428
nasopharyngeal carcinoma 7 | 1,024
non-small cell lung carcinoma 7 | 302
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,911
spina bifida 7 | 1,053
Adenocarcinoma of lung 6 | 140
Atrial Fibrillation 6 | 120
Diabetes Mellitus, Non-Insulin-Dependent 6 | 140
Malaria 6 | 155
Neoplasm Invasiveness 6 | 151
Parkinson's disease 6 | 378
Toxic encephalopathy 6 | 139
astrocytoma 6 | 1,113
dermatomyositis 6 | 941
hepatocellular carcinoma 6 | 536

Tissue

Endocrine System 65 | 18,159
Liver and Pancreas 65 | 16,750
Blood and immune system 64 | 16,909
Digestive Tract 64 | 17,369
Female tissues 64 | 17,400
Male tissues 64 | 17,142
Nervous System 64 | 16,725
Skin and soft tissues 64 | 17,230
Urinary Tract 64 | 16,678
Respiratory system 62 | 16,393
Cardiovascular System 61 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 21 | 12,091
Transcription Factor 7 | 1,400
Kinase 5 | 634
Ion Channel 4 | 344
GPCR 1 | 408

GO Process

cellular response to drug 65 | 65
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol-glycan-specific phospholipase D GPLD1 Tbio Enzyme -2.08209 126.8 222
Ankyrin repeat domain-containing protein 1 ANKRD1 Tbio Non-IDG -1.79794 62.3 159
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Major prion protein PRNP Tchem Non-IDG -3.45326 5611.1 484
Fibroblast growth factor 21 FGF21 Tbio Non-IDG -2.81854 777.4 443
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.78263 593.3 412
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
5-hydroxytryptamine receptor 1B HTR1B Tclin GPCR -3.03042 1068.4 211
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147