Development Level

Tbio 38 | 11,445
Tchem 13 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased total body fat amoun... 4 | 207
preweaning lethality, complete... 4 | 979
enlarged heart 3 | 210
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
enlarged kidney 2 | 14
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
small testis 2 | 58
tremors 2 | 39
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal locomotor behavior 1 | 24
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased pulmonary respirator... 1 | 5
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged stomach 1 | 2
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
prolonged PQ interval 1 | 5
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

Carcinoma 38 | 11,493
glioblastoma 36 | 5,792
ovarian cancer 34 | 8,520
ependymoma 33 | 4,679
medulloblastoma, large-cell 33 | 6,241
osteosarcoma 33 | 7,950
atypical teratoid / rhabdoid tumor 29 | 5,112
psoriasis 26 | 6,694
Breast cancer 24 | 3,578
adult high grade glioma 23 | 3,801
lung cancer 23 | 4,740
oligodendroglioma 22 | 2,850
astrocytic glioma 20 | 2,597
group 3 medulloblastoma 20 | 4,104
primitive neuroectodermal tumor 20 | 3,035
Astrocytoma, Pilocytic 19 | 3,081
pancreatic cancer 18 | 2,398
Cancer 17 | 2,499
lung adenocarcinoma 17 | 2,716
lung carcinoma 16 | 2,843
non-small cell lung cancer 15 | 2,890
Kidney cancer 14 | 2,613
malignant mesothelioma 14 | 3,232
invasive ductal carcinoma 13 | 2,951
subependymal giant cell astrocytoma 13 | 2,287
colon cancer 12 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
breast carcinoma 11 | 1,638
group 4 medulloblastoma 11 | 1,855
Autosomal recessive predisposition 10 | 1,442
Pick disease 10 | 1,894
adrenocortical carcinoma 10 | 1,428
pituitary cancer 10 | 1,972
ulcerative colitis 10 | 1,819
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
astrocytoma 9 | 1,146
non primary Sjogren syndrome sicca 9 | 891
tuberculosis 9 | 2,010
Epilepsy 8 | 792
Liver Cirrhosis, Experimental 8 | 769
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,312
nephrosclerosis 8 | 333
primary pancreatic ductal adenocarcinoma 8 | 1,109
Amyotrophic lateral sclerosis 7 | 451
Atopic dermatitis 7 | 952
Down syndrome 7 | 499
Intellectual disability 7 | 1,016
Lung Neoplasms 7 | 232
Obesity 7 | 678
active Crohn's disease 7 | 922
acute myeloid leukemia 7 | 783
aldosterone-producing adenoma 7 | 665
diabetes mellitus 7 | 1,728
gastric cancer 7 | 459
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Bipolar Disorder 6 | 666
Carcinoma, Hepatocellular 6 | 228
Hypertension 6 | 396
Hypertensive disease 6 | 292
Kidney disease 6 | 430
Liver cancer 6 | 604
Liver carcinoma 6 | 240
Melanoma 6 | 711
Parkinson's disease 6 | 392
Status Epilepticus 6 | 98
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
cutaneous lupus erythematosus 6 | 1,057
hepatocellular carcinoma 6 | 547
progressive supranuclear palsy 6 | 676
pterygium 6 | 76
Alzheimer's disease 5 | 658
Cell Transformation, Neoplastic 5 | 97
Schizophrenia 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
fibroadenoma 5 | 559
Asthma 4 | 385
Atherosclerosis 4 | 291
Cocaine-Related Disorders 4 | 92
Duchenne muscular dystrophy 4 | 601
Endometrial cancer 4 | 311
Heart disease 4 | 306
Muscle hypotonia 4 | 571
Neoplastic Cell Transformation 4 | 89
Neuropathy 4 | 261
Orbital separation excessive 4 | 244
Polycystic ovary syndrome 4 | 360
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074

Tissue

Digestive Tract 56 | 17,369
Skin and soft tissues 56 | 17,230
Endocrine System 55 | 18,159
Nervous System 55 | 16,725
Female tissues 54 | 17,400
Liver and Pancreas 54 | 16,750
Male tissues 54 | 17,142
Urinary Tract 54 | 16,678
Blood and immune system 53 | 16,909
Respiratory system 51 | 16,393
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 15 | 4,145
Transcription Factor 8 | 1,400
Ion Channel 7 | 344
Kinase 5 | 634
Transporter 2 | 473

GO Process

cellular response to calcium i... 58 | 58
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Calcium-binding mitochondrial carrier protein SCaMC-3 SLC25A23 Tbio Transporter -0.72246 7.27 53
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Copine-6 CPNE6 Tbio Non-IDG -0.79740 6.43 129
Copine-1 CPNE1 Tbio Non-IDG -1.04880 11.6 151
Ras GTPase-activating protein 4 RASA4 Tbio Enzyme -2.47836 299.2 58
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Endonuclease G, mitochondrial ENDOG Tbio Enzyme -2.22791 175.9 334
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
Late cornified envelope protein 1D LCE1D Tbio Non-IDG 0.32 0.29 0