Development Level

Tclin 4 | 613
Tbio 2 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
edema 2 | 59
abnormal facial morphology 1 | 17
abnormal placenta vasculature 1 | 2
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased circulating glucose ... 1 | 126
decreased heart rate variabili... 1 | 13
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased startle reflex 1 | 112
prenatal lethality 1 | 28
respiratory system phenotype 1 | 2

Disease

Carcinoma 7 | 11,493
psoriasis 7 | 6,694
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Malignant hyperthermia 4 | 26
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
glioblastoma 4 | 5,792
ovarian cancer 4 | 8,520
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Endometrial cancer 3 | 311
Heart disease 3 | 306
Liver cancer 3 | 604
Lymphoid leukemia 3 | 160
Myocardial Ischemia 3 | 169
Myopathy 3 | 185
Pick disease 3 | 1,894
Seizures 3 | 596
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Catecholaminergic polymorphic ventricular tachycardia 2 | 12
Central core myopathy 2 | 5
DOID:2627 2 | 94
Dizziness 2 | 26
Epilepsy 2 | 792
Generalized muscle weakness 2 | 57
Hypertensive disorder 2 | 56
Hypokalemic periodic paralysis 2 | 11
Immune system cancer 2 | 140
Malignant Hyperthermia Prevention 2 | 2
Malignant hyperpyrexia due to anesthesia 2 | 10
Melanoma 2 | 711
Muscle Cramp 2 | 55
Muscle Spasticity of Cerebral Origin 2 | 8
Muscle spasticity of spinal origin 2 | 8
Myocardial Infarction 2 | 151
Neurodegenerative Disorders 2 | 79
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Obesity 2 | 678
Polymorphic catecholergic ventricular tachycardia 2 | 3
Respiratory Insufficiency 2 | 132
Rhabdomyolysis 2 | 15
Schizophrenia 2 | 1,160
Skeletal muscle atrophy 2 | 139
Skin cancer 2 | 469
Spasticity 2 | 26
Sudden death 2 | 16
Syncope 2 | 22
Tachycardia 2 | 43
Tachycardia, Ventricular 2 | 22
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) 2 | 5
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy 2 | 4
Vertigo 2 | 29
acute quadriplegic myopathy 2 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
muscle degeneration 2 | 139
non-small cell lung carcinoma 2 | 317
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Acquired flat foot 1 | 72
Brain cancer 1 | 30
Centronuclear myopathy 1 | 27
DOID:9917 1 | 31
Diabetic Cardiomyopathies 1 | 10
Elevated heart rate 1 | 25
Flatfoot 1 | 73
Hydrops Fetalis 1 | 21
Hyperglycemia 1 | 137
Hyperkalemia 1 | 17
Hyperphosphatemia (disorder) 1 | 17
Hypokalemia 1 | 52
Hypomagnesemia 1 | 12
Hypotension 1 | 82
Joint laxity 1 | 54
Malignant glioma 1 | 26
Myocardial Reperfusion Injury 1 | 37
Narrow face 1 | 54
Neonatal onset 1 | 21
Pain 1 | 103
Palpitations 1 | 18
SERUM PHOSPHATE ELEVATED 1 | 14
Thin face 1 | 54

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Liver and Pancreas 7 | 16,750

Target Family

Ion Channel 4 | 344
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Transporter 1 | 473

GO Process

cellular response to caffeine 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Ryanodine receptor 3 RYR3 Tclin Ion Channel -2.15460 142.3 16
Ryanodine receptor 1 RYR1 Tclin Ion Channel -3.00978 1018.9 103
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.52990 349.1 141
Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S Tclin Ion Channel -2.21321 163.9 114
Glutathione S-transferase Mu 2 GSTM2 Tchem Enzyme -2.23927 166.1 164
Calsequestrin-2 CASQ2 Tbio Non-IDG -1.93799 89.4 204
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PPARGC1A Tbio Non-IDG -2.86449 728.1 274