Development Level

Tbio 19 | 11,651
Tchem 11 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
enlarged heart 1 | 210
increased lean body mass 1 | 172
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Cancer 21 | 2,499
ovarian cancer 20 | 8,520
lung cancer 18 | 4,740
osteosarcoma 17 | 7,950
Carcinoma 15 | 11,493
atypical teratoid / rhabdoid tumor 15 | 5,112
malignant mesothelioma 15 | 3,232
psoriasis 15 | 6,694
Breast cancer 14 | 3,578
medulloblastoma, large-cell 14 | 6,241
glioblastoma 13 | 5,792
non-small cell lung cancer 12 | 2,890
Alzheimer's disease 11 | 658
Schizophrenia 11 | 1,160
diabetes mellitus 11 | 1,728
group 3 medulloblastoma 11 | 4,104
Endometriosis 10 | 540
breast carcinoma 10 | 1,638
colon cancer 10 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Arthritis 9 | 290
Disease Models, Animal 9 | 155
Kidney disease 9 | 430
Lung Neoplasms 9 | 232
Obesity 9 | 678
acute quadriplegic myopathy 9 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Asthma 8 | 385
Astrocytoma, Pilocytic 8 | 3,081
Hypertensive disease 8 | 292
Liver Cirrhosis, Experimental 8 | 769
Reperfusion Injury 8 | 86
Stomach Neoplasms 8 | 300
Toxic encephalopathy 8 | 141
Vascular disease 8 | 319
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
tuberculosis 8 | 2,010
Breast Neoplasms 7 | 445
Carcinoma, Squamous Cell 7 | 110
Cell Transformation, Neoplastic 7 | 97
Cholestasis, Extrahepatic 7 | 25
Heart disease 7 | 306
Hypertension 7 | 396
Mammary Neoplasms 7 | 425
Neoplasm Invasiveness 7 | 161
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
Rheumatoid arthritis 7 | 1,191
Squamous cell carcinoma 7 | 129
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
cystic fibrosis 7 | 1,696
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
primary pancreatic ductal adenocarcinoma 7 | 1,109
subependymal giant cell astrocytoma 7 | 2,287
Autosomal recessive predisposition 6 | 1,442
Depressive disorder 6 | 409
Liver disease 6 | 237
Lung disease 6 | 142
Mental Depression 6 | 333
Neoplastic Cell Transformation 6 | 89
Neurodegenerative disease 6 | 414
Osteoporosis 6 | 363
cutaneous lupus erythematosus 6 | 1,057
ependymoma 6 | 4,679
pituitary cancer 6 | 1,972
Atherosclerosis 5 | 291
Bipolar Disorder 5 | 666
Brain Ischemia 5 | 110
Carcinoma, Hepatocellular 5 | 228
Diabetes Mellitus, Experimental 5 | 108
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Down syndrome 5 | 499
Eye disease 5 | 62
Hyperalgesia 5 | 83
Hyperglycemia 5 | 137
Intellectual disability 5 | 1,016
Liver carcinoma 5 | 240
Neoplasm Metastasis 5 | 168
Ovarian Neoplasms 5 | 102
Pick disease 5 | 1,894
Trigeminal Neuralgia 5 | 24
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
adult high grade glioma 5 | 3,801
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
nephrosclerosis 5 | 333
oligodendroglioma 5 | 2,850
ovarian neoplasm 5 | 99
primitive neuroectodermal tumor 5 | 3,035
Kidney cancer 4 | 2,613
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
Kinase 7 | 634
Transcription Factor 3 | 1,400
Ion Channel 1 | 344

GO Process

cellular response to cadmium i... 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
Metallothionein-1F MT1F Tbio Non-IDG -1.17171 15.1 11
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.72599 482.7 786
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK Tchem Kinase -2.36360 203.6 1101
Neutrophil cytosol factor 1 NCF1 Tbio Non-IDG -2.58838 554.8 675
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103