Development Level

Tbio 28 | 11,445
Tchem 9 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
impaired glucose tolerance 2 | 75
prenatal lethality 2 | 28
preweaning lethality, incomple... 2 | 499
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating insulin ... 1 | 76
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased mean corpuscular hem... 1 | 96
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
microcephaly 1 | 1
prenatal lethality prior to he... 1 | 87
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Carcinoma 26 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 22 | 7,950
glioblastoma 20 | 5,792
Cancer 17 | 2,499
ependymoma 16 | 4,679
medulloblastoma, large-cell 16 | 6,241
psoriasis 14 | 6,694
lung cancer 13 | 4,740
Breast cancer 12 | 3,578
Schizophrenia 11 | 1,160
Vascular disease 11 | 319
subependymal giant cell astrocytoma 11 | 2,287
malignant mesothelioma 10 | 3,232
tuberculosis 10 | 2,010
atypical teratoid / rhabdoid tumor 9 | 5,112
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Multiple myeloma 7 | 1,332
Rheumatoid arthritis 7 | 1,191
oligodendroglioma 7 | 2,850
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
Epilepsy 6 | 792
Waldenstrons macroglobulinemia 6 | 765
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
Bipolar Disorder 5 | 666
Cardiomyopathies 5 | 110
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Hepatomegaly 5 | 285
Hyperglycemia 5 | 137
Lung Neoplasms 5 | 232
Mental and motor retardation 5 | 608
Obesity 5 | 678
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
primitive neuroectodermal tumor 5 | 3,035
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Arthritis 4 | 290
Autosomal recessive predisposition 4 | 1,442
Brain Ischemia 4 | 110
Depressive disorder 4 | 409
Diabetes Mellitus, Experimental 4 | 108
Disease Models, Animal 4 | 155
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Liver Failure, Acute 4 | 29
Mental Depression 4 | 333
Muscle hypotonia 4 | 571
Ovarian Neoplasms 4 | 102
Parkinson's disease 4 | 392
Status Epilepticus 4 | 98
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
ovarian neoplasm 4 | 99
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Anemia 3 | 365
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Heart disease 3 | 306
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurodegenerative disease 3 | 414
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
gastric cancer 3 | 459
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
limb girdle muscular dystrophy 2A 3 | 213
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678

Target Family

Non-IDG 25 | 12,091
Kinase 9 | 634
Enzyme 5 | 4,145
Transcription Factor 2 | 1,400
Transporter 1 | 473

GO Process

cellular response to amino aci... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GATOR complex protein MIOS MIOS Tdark Non-IDG -1.44864 28.1 21
GATOR complex protein WDR24 WDR24 Tdark Non-IDG 0.16 1.02 28
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Sestrin-2 SESN2 Tbio Non-IDG -1.88129 92.6 176
Death-associated protein-like 1 DAPL1 Tbio Non-IDG -0.91439 8.29 84
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
eIF-2-alpha kinase activator GCN1 GCN1 Tdark Non-IDG -1.38567 23.9 50
KICSTOR complex protein SZT2 SZT2 Tbio Non-IDG -0.87849 6.65 52