Development Level

Tbio 8 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

decreased body weight 2 | 161
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal iris morphology 1 | 13
abnormal tail movements 1 | 12
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17

Disease

Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
Breast cancer 6 | 3,578
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
Ataxia telangiectasia 3 | 34
Breast Neoplasms 3 | 445
Epilepsy 3 | 792
Mammary Neoplasms 3 | 425
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
Seizures 3 | 596
Waldenstrons macroglobulinemia 3 | 765
Werner syndrome 3 | 29
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Adenocarcinoma of lung 2 | 142
Adenoma 2 | 167
Alcoholic Intoxication, Chronic 2 | 289
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Bloom syndrome 2 | 29
Colorectal Neoplasms 2 | 243
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Disease Models, Animal 2 | 155
Duchenne muscular dystrophy 2 | 601
Fanconi anemia 2 | 56
Fibrosis 2 | 44
Inflammatory Bowel Diseases 2 | 35
Liver cancer 2 | 604
Mental Depression 2 | 333
Microcephaly 2 | 166
Neurodegenerative disease 2 | 414
Nijmegen breakage syndrome 2 | 24
Nystagmus 2 | 317
Obesity 2 | 678
Prenatal onset 2 | 139
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Severe combined immunodeficiency 2 | 51
Short stature 2 | 531
Squamous cell carcinoma 2 | 129
Strabismus 2 | 270
Systemic lupus erythematosus 2 | 194
Ventricular Septal Defects 2 | 119
Xeroderma pigmentosum 2 | 43
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
interstitial lung disease 2 | 298
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
Abnormal nasal morphology 1 | 16
Absent finger 1 | 4
Axonal degeneration 1 | 7
Bowed and upward slanting eyebrows 1 | 41
Congenital hypoplasia of radius 1 | 23
Cutis marmorata 1 | 32
Flexion contracture - elbow 1 | 32
Paranasal Sinus Diseases 1 | 34
Premature canities 1 | 24
Radial ray hypoplasia 1 | 23
Simple syndactyly of toes, first web space 1 | 23
Single transverse palmar crease 1 | 29
Thick, flared eyebrows 1 | 41
Weak cry 1 | 17
Widely spaced teeth 1 | 31

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

cellular response to X-ray 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 NUCKS1 Tbio Enzyme -1.43623 29.2 148
Hepcidin HAMP Tbio Non-IDG -3.30891 2214.4 306
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Dynamin-2 DNM2 Tchem Non-IDG -2.43547 282.5 143
X-ray repair cross-complementing protein 6 XRCC6 Tbio Non-IDG -2.86424 688.3 865
Serine-protein kinase ATM ATM Tchem Kinase -3.57054 3681.6 1024
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.40092 279.5 264
Secreted frizzled-related protein 2 SFRP2 Tbio Non-IDG -2.15400 154.0 181