Development Level

Tbio 21 | 10,625
Tchem 17 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal neural tube closure 1 | 37
abnormal seminal vesicle morph... 1 | 47
abnormal vocalization 1 | 21
decreased B cell number 1 | 30
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased granulocyte number 1 | 8
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to o... 1 | 148
impaired glucose tolerance 1 | 52
increased T cell number 1 | 15
increased body length 1 | 20
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased heart weight 1 | 37
increased lymphocyte cell numb... 1 | 9
preweaning lethality, incomple... 1 | 260
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
straub tail 1 | 26

Disease

ovarian cancer 27 | 8,484
osteosarcoma 26 | 7,933
Cancer 25 | 2,346
medulloblastoma, large-cell 22 | 6,234
glioblastoma 21 | 5,572
psoriasis 21 | 6,685
lung cancer 19 | 4,466
atypical teratoid / rhabdoid tumor 16 | 4,369
primitive neuroectodermal tumor 13 | 3,031
Breast cancer 12 | 3,094
non-small cell lung cancer 12 | 2,798
pediatric high grade glioma 12 | 2,712
Carcinoma 11 | 2,147
group 3 medulloblastoma 11 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
invasive ductal carcinoma 10 | 2,950
juvenile dermatomyositis 10 | 1,189
lung adenocarcinoma 10 | 2,713
Rheumatoid Arthritis 9 | 1,160
adrenocortical carcinoma 9 | 1,427
astrocytoma 9 | 1,493
diabetes mellitus 9 | 1,663
oligodendroglioma 9 | 2,849
Multiple myeloma 8 | 1,327
acute quadriplegic myopathy 8 | 1,157
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
malignant mesothelioma 8 | 3,162
pilocytic astrocytoma 8 | 3,086
Prostatic Neoplasms 7 | 471
adult high grade glioma 7 | 2,148
breast carcinoma 7 | 1,614
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,299
nasopharyngeal carcinoma 7 | 1,056
pancreatic cancer 7 | 2,300
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 1,557
Amyotrophic Lateral Sclerosis 6 | 431
Bladder Neoplasm 6 | 109
Colonic Neoplasms 6 | 126
Endometriosis 6 | 535
acute myeloid leukemia 6 | 780
dermatomyositis 6 | 933
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
medulloblastoma 6 | 1,524
Adenoid Cystic Carcinoma 5 | 99
Alzheimer's disease 5 | 644
Chronic Lymphocytic Leukemia 5 | 242
Colorectal Neoplasms 5 | 217
Intellectual disability 5 | 573
Lung Neoplasms 5 | 171
Lymphoid leukemia 5 | 69
Mammary Neoplasms 5 | 410
Neoplasm Metastasis 5 | 138
Squamous cell carcinoma of esophagus 5 | 82
lung carcinoma 5 | 2,844
pituitary cancer 5 | 1,972
posterior fossa group A ependymoma 5 | 1,511
ulcerative colitis 5 | 2,087
Adenocarcinoma 4 | 115
Barrett's esophagus 4 | 183
Brain Ischemia 4 | 87
Brain disease 4 | 83
Carcinoma, Transitional Cell 4 | 31
Down syndrome 4 | 548
Familial adenomatous polyposis 4 | 31
IGA Glomerulonephritis 4 | 454
Kidney cancer 4 | 118
Kidney disease 4 | 396
Melanoma 4 | 261
Neurodegenerative disease 4 | 383
Pancreatic Neoplasm 4 | 79
Parkinson's disease 4 | 364
Peripheral Neuropathy 4 | 303
Small cell carcinoma of lung 4 | 45
Stomach Neoplasms 4 | 282
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
colon cancer 4 | 1,475
ependymoma 4 | 2,514
esophageal adenocarcinoma 4 | 737
pancreatic carcinoma 4 | 567
posterior fossa group B ependymoma 4 | 1,530
spina bifida 4 | 1,064
Adenoma 3 | 165
Disease Progression 3 | 125
Hypertensive disease 3 | 193
Liver carcinoma 3 | 217
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 332
Schizophrenia 3 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,665
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
non-small cell lung carcinoma 3 | 413
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis and treatment for 6 months 3 | 686

Tissue

Blood and immune system 42 | 17,995
Cardiovascular System 42 | 17,958
Digestive Tract 42 | 18,473
Endocrine System 42 | 18,512
Female tissues 42 | 18,647
Liver and Pancreas 42 | 18,136
Male tissues 42 | 17,969
Nervous System 42 | 18,561
Respiratory system 42 | 17,484
Skin and soft tissues 42 | 18,115
Urinary Tract 42 | 18,444

Target Family

Non-IDG 14 | 11,971
Enzyme 11 | 4,146
Transcription Factor 8 | 1,400
Kinase 5 | 634
Epigenetic 4 | 242

GO Process

cellular response to UV 42 | 42
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.75991 594.0 437
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
NEDD4-binding protein 1 N4BP1 Tdark Non-IDG -0.53701 2.75 85
Ubiquitin carboxyl-terminal hydrolase 28 USP28 Tbio Enzyme -1.36401 22.9 168
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.75838 5701.8 723
TP53-regulated inhibitor of apoptosis 1 TRIAP1 Tbio Non-IDG -2.36887 245.1 9
Aquaporin-1 AQP1 Tbio Non-IDG -3.04203 1040.5 321