Development Level

Tbio 31 | 11,651
Tchem 15 | 1,388
Tclin 2 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
hypoactivity 3 | 132
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased lymphocyte cell numb... 2 | 32
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal spinal cord morpholog... 1 | 9
abnormal vocalization 1 | 21
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased fluid intake 1 | 3
decreased granulocyte number 1 | 6
decreased neutrophil cell numb... 1 | 42
embryonic growth retardation 1 | 106
increased T cell number 1 | 6
increased body length 1 | 32
increased circulating glucose ... 1 | 24
increased circulating total pr... 1 | 28
prenatal lethality 1 | 28
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19

Disease

Carcinoma 33 | 11,493
ovarian cancer 30 | 8,520
osteosarcoma 29 | 7,950
Cancer 28 | 2,499
glioblastoma 26 | 5,792
medulloblastoma, large-cell 24 | 6,241
lung cancer 23 | 4,740
psoriasis 23 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
group 3 medulloblastoma 20 | 4,104
Breast cancer 17 | 3,578
primitive neuroectodermal tumor 16 | 3,035
Kidney cancer 13 | 2,613
adult high grade glioma 13 | 3,801
non-small cell lung cancer 13 | 2,890
ependymoma 12 | 4,679
juvenile dermatomyositis 12 | 1,187
Rheumatoid arthritis 11 | 1,191
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
Multiple myeloma 9 | 1,332
acute quadriplegic myopathy 9 | 1,158
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Astrocytoma, Pilocytic 8 | 3,081
Prostatic Neoplasms 8 | 495
Short stature 8 | 531
acute myeloid leukemia 8 | 783
subependymal giant cell astrocytoma 8 | 2,287
Colonic Neoplasms 7 | 142
Cryptorchidism 7 | 296
Intellectual disability 7 | 1,016
Lymphoid leukemia 7 | 160
Schizophrenia 7 | 1,160
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
nasopharyngeal carcinoma 7 | 1,058
pediatric high grade glioma 7 | 1,064
Acquired scoliosis 6 | 281
Amyotrophic lateral sclerosis 6 | 451
Bipolar Disorder 6 | 666
Bladder Neoplasm 6 | 112
Breast Neoplasms 6 | 445
Carcinoma, Squamous Cell 6 | 110
Curvature of spine 6 | 282
Deafness 6 | 198
Endometrial cancer 6 | 311
Endometriosis 6 | 540
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Melanoma 6 | 711
Micrognathism 6 | 275
Seizures 6 | 596
Squamous cell carcinoma 6 | 129
Stomach Neoplasms 6 | 300
Urinary Bladder Neoplasms 6 | 114
Vascular disease 6 | 319
Waldenstrons macroglobulinemia 6 | 765
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
Adenocarcinoma 5 | 122
Adenocarcinoma of lung 5 | 142
Adenocarcinoma of lung (disorder) 5 | 60
Adenoid Cystic Carcinoma 5 | 99
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Carcinoma, Adenoid Cystic 5 | 99
Cataract 5 | 297
Chronic Lymphocytic Leukemia 5 | 262
Colorectal Neoplasms 5 | 243
Congenital deafness 5 | 185
Delayed bone age 5 | 136
Enophthalmos 5 | 75
Epilepsy 5 | 792
Esophageal Squamous Cell Carcinoma 5 | 77
Failure to gain weight 5 | 365
Glaucoma 5 | 239
Hearing Loss, Partial 5 | 185
Immune system cancer 5 | 140
Lung Neoplasms 5 | 232
Mammary Neoplasms 5 | 425
Neoplasm Metastasis 5 | 168
Pediatric failure to thrive 5 | 365
Pick disease 5 | 1,894
Squamous cell carcinoma of esophagus 5 | 77
Sunken eyes 5 | 63
colon cancer 5 | 1,478
hearing impairment 5 | 199
lung carcinoma 5 | 2,843
pituitary cancer 5 | 1,972
ulcerative colitis 5 | 1,819

Tissue

Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Nervous System 50 | 16,725
Respiratory system 50 | 16,393
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 13 | 4,145
Transcription Factor 8 | 1,400
Kinase 6 | 634
Epigenetic 4 | 242

GO Process

cellular response to UV 50 | 50
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
Nucleolar complex protein 2 homolog NOC2L Tbio Non-IDG -2.54468 350.1 85
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Ubiquitin carboxyl-terminal hydrolase 28 USP28 Tbio Enzyme -1.43386 23.9 194
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
Transmembrane protein 161A TMEM161A Tdark Non-IDG 0.22 0.80 102