Development Level

Tbio 162 | 11,651
Tchem 42 | 1,388
Tdark 7 | 6,593
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 4 | 125
RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 20 | 979
abnormal bone structure 6 | 187
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to o... 5 | 239
abnormal embryo size 4 | 220
abnormal gait 4 | 69
decreased bone mineral density 4 | 126
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased circulating alanine ... 3 | 47
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
increased bone mineral density 3 | 72
increased circulating alkaline... 3 | 122
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal limb morphology 2 | 13
abnormal lung morphology 2 | 26
decreased basophil cell number 2 | 16
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating insulin ... 2 | 76
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating glucose ... 2 | 24
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
male infertility 2 | 123
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vitelline vasculature... 1 | 6
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hemorrhage 1 | 23
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
iris synechia 1 | 3
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39

Disease

Carcinoma 163 | 11,493
ovarian cancer 138 | 8,519
osteosarcoma 126 | 7,950
medulloblastoma, large-cell 96 | 6,241
lung cancer 92 | 4,740
psoriasis 87 | 6,694
glioblastoma 81 | 5,792
Cancer 80 | 2,499
atypical teratoid / rhabdoid tumor 74 | 5,112
group 3 medulloblastoma 73 | 4,104
Breast cancer 66 | 3,577
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,290
malignant mesothelioma 57 | 3,232
ependymoma 53 | 4,679
Kidney cancer 49 | 2,613
primitive neuroectodermal tumor 49 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,988
adult high grade glioma 44 | 3,801
invasive ductal carcinoma 43 | 2,950
oligodendroglioma 41 | 2,850
non-small cell lung cancer 40 | 2,890
Pick disease 39 | 1,894
astrocytic glioma 39 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,954
pancreatic cancer 34 | 2,398
ulcerative colitis 32 | 1,819
pituitary cancer 31 | 1,972
adrenocortical carcinoma 30 | 1,428
lung adenocarcinoma 29 | 2,716
subependymal giant cell astrocytoma 29 | 2,287
juvenile dermatomyositis 28 | 1,187
tuberculosis 27 | 2,010
Rheumatoid arthritis 26 | 1,191
breast carcinoma 26 | 1,637
diabetes mellitus 26 | 1,728
Astrocytoma, Pilocytic 25 | 3,081
ductal carcinoma in situ 25 | 1,744
lung carcinoma 25 | 2,843
Intellectual disability 24 | 1,016
Multiple myeloma 24 | 1,332
colon cancer 24 | 1,478
Breast Neoplasms 23 | 445
acute quadriplegic myopathy 22 | 1,158
interstitial cystitis 21 | 2,312
nasopharyngeal carcinoma 21 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Mammary Neoplasms 20 | 425
Schizophrenia 20 | 1,160
Prostatic Neoplasms 19 | 495
dermatomyositis 19 | 966
Atopic dermatitis 18 | 952
Autosomal recessive predisposition 18 | 1,442
astrocytoma 18 | 1,146
progressive supranuclear palsy 18 | 676
group 4 medulloblastoma 17 | 1,855
Dull intelligence 16 | 645
Liver cancer 16 | 604
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
cystic fibrosis 16 | 1,695
primary pancreatic ductal adenocarcinoma 16 | 1,108
Fanconi anemia 15 | 56
Lung Neoplasms 15 | 232
Short stature 15 | 531
acute myeloid leukemia 15 | 783
medulloblastoma 15 | 720
pediatric high grade glioma 15 | 1,064
Alzheimer's disease 14 | 658
Amyotrophic lateral sclerosis 14 | 451
Ataxia telangiectasia 14 | 34
Nijmegen breakage syndrome 14 | 24
Obesity 14 | 678
Epilepsy 13 | 792
Melanoma 13 | 711
Waldenstrons macroglobulinemia 13 | 765
primary Sjogren syndrome 13 | 735
Bipolar Disorder 12 | 666
Chronic Lymphocytic Leukemia 12 | 262
Lymphoid leukemia 12 | 160
Small head 12 | 374
Splenomegaly 12 | 190
Squamous cell carcinoma 12 | 129
gastric cancer 12 | 459
hepatocellular carcinoma 12 | 547
tuberculosis and treatment for 6 months 12 | 409
Anemia 11 | 365
Carcinoma, Squamous Cell 11 | 110
Endometriosis 11 | 540
Immune system cancer 11 | 140
Stomach Neoplasms 11 | 300
spina bifida 11 | 1,074
Acquired scoliosis 10 | 281
Cognitive delay 10 | 608
Curvature of spine 10 | 282
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Seizures 10 | 596
gastric carcinoma 10 | 807

Tissue

Endocrine System 214 | 18,159
Blood and immune system 213 | 16,909
Digestive Tract 213 | 17,369
Female tissues 213 | 17,400
Liver and Pancreas 213 | 16,750
Male tissues 213 | 17,142
Nervous System 213 | 16,725
Respiratory system 213 | 16,393
Skin and soft tissues 213 | 17,230
Urinary Tract 213 | 16,678
Cardiovascular System 210 | 15,192

Target Family

Non-IDG 106 | 12,091
Enzyme 56 | 4,145
Kinase 25 | 634
Transcription Factor 19 | 1,400
Epigenetic 11 | 242

GO Process

cellular response to DNA damag... 217 | 217
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing adapter protein with coiled-coil WAC Tbio Non-IDG -1.93384 84.9 87
DNA helicase MCM9 MCM9 Tbio Enzyme -1.14882 14.6 58
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tbio Epigenetic -2.14139 133.9 254
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
BRISC and BRCA1-A complex member 2 BABAM2 Tbio Non-IDG -1.84649 70.2 156
Protein AATF AATF Tbio Non-IDG -2.20561 160.5 230
CDKN2A-interacting protein CDKN2AIP Tbio Non-IDG -0.74312 7.49 147
Malignant T-cell-amplified sequence 1 MCTS1 Tbio Non-IDG -0.79616 5.89 149
Ubiquitin carboxyl-terminal hydrolase 16 USP16 Tbio Enzyme -0.67094 5.97 248
Guanine nucleotide exchange factor VAV3 VAV3 Tbio Non-IDG -1.82116 74.0 249