Development Level

Tbio 56 | 11,178
Tchem 19 | 1,885
Tdark 8 | 6,569
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased body weight 4 | 161
abnormal bone mineralization 3 | 38
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal kidney morphology 2 | 65
abnormal tail morphology 2 | 25
abnormal vocalization 2 | 21
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal defecation 1 | 1
abnormal esophagus morphology 1 | 5
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal pancreas morphology 1 | 13
abnormal radius morphology 1 | 8
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal thyroid gland morphol... 1 | 3
abnormal tibia morphology 1 | 14
abnormal trachea morphology 1 | 3
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
absent lymph nodes 1 | 3
absent vibrissae 1 | 12
anophthalmia 1 | 33
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged liver 1 | 2
enlarged spleen 1 | 41
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
long tail 1 | 1
long tibia 1 | 25
mammalian phenotype 1 | 17
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58
thick tail 1 | 1
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

ovarian cancer 56 | 8,297
Carcinoma 54 | 11,192
osteosarcoma 46 | 7,766
psoriasis 36 | 6,514
glioblastoma 32 | 5,635
atypical teratoid / rhabdoid tumor 30 | 4,971
lung cancer 30 | 4,607
medulloblastoma, large-cell 27 | 6,086
Breast cancer 22 | 3,469
ependymoma 22 | 4,559
Cancer 21 | 2,388
group 3 medulloblastoma 18 | 4,002
non-small cell lung cancer 17 | 2,799
pancreatic cancer 17 | 2,322
Multiple myeloma 16 | 1,296
astrocytic glioma 16 | 2,530
invasive ductal carcinoma 16 | 2,867
malignant mesothelioma 16 | 3,135
oligodendroglioma 16 | 2,768
Kidney cancer 15 | 2,548
adult high grade glioma 15 | 3,701
Astrocytoma, Pilocytic 14 | 3,006
Autosomal recessive predisposition 14 | 1,407
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,204
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,872
primitive neuroectodermal tumor 13 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,902
lung adenocarcinoma 12 | 2,627
lung carcinoma 12 | 2,755
juvenile dermatomyositis 11 | 1,147
diabetes mellitus 10 | 1,683
group 4 medulloblastoma 10 | 1,806
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,911
primary pancreatic ductal adenocarcinoma 10 | 1,071
tuberculosis 10 | 1,963
Pick disease 9 | 1,856
Schizophrenia 9 | 1,136
astrocytoma 8 | 1,113
dermatomyositis 8 | 941
esophageal adenocarcinoma 8 | 696
interstitial cystitis 8 | 2,237
pediatric high grade glioma 8 | 1,035
pituitary cancer 8 | 1,915
ulcerative colitis 8 | 1,765
acute quadriplegic myopathy 7 | 1,133
cystic fibrosis 7 | 1,629
subependymal giant cell astrocytoma 7 | 2,230
Bipolar Disorder 6 | 646
Breast Neoplasms 6 | 423
Mammary Neoplasms 6 | 403
adrenocortical carcinoma 6 | 1,385
breast carcinoma 6 | 1,589
medulloblastoma 6 | 702
Epilepsy 5 | 775
Obesity 5 | 655
Parkinson's disease 5 | 378
Prostatic Neoplasms 5 | 472
Waldenstrons macroglobulinemia 5 | 742
active Crohn's disease 5 | 882
chronic rhinosinusitis 5 | 505
nasopharyngeal carcinoma 5 | 1,024
pancreatic carcinoma 5 | 555
progressive supranuclear palsy 5 | 656
tuberculosis and treatment for 6 months 5 | 399
Alzheimer's disease 4 | 640
Amyotrophic lateral sclerosis 4 | 437
Chemical and Drug Induced Liver Injury 4 | 188
Cognitive delay 4 | 596
Down syndrome 4 | 480
Duchenne muscular dystrophy 4 | 587
Global developmental delay 4 | 596
Hepatomegaly 4 | 280
Infantile onset 4 | 236
Intellectual disability 4 | 998
Liver Cirrhosis 4 | 173
Liver Cirrhosis, Experimental 4 | 733
Liver neoplasms 4 | 126
Melanoma 4 | 689
Mental and motor retardation 4 | 596
Multiple Sclerosis 4 | 527
Muscle hypotonia 4 | 562
Osteoporosis 4 | 348
Polycystic ovary syndrome 4 | 348
Seizures 4 | 584
gastric carcinoma 4 | 781
non primary Sjogren syndrome sicca 4 | 861
Acquired scoliosis 3 | 274
Allergic rhinitis 3 | 93
Anemia 3 | 353
Atherosclerosis 3 | 276
Atopic dermatitis 3 | 915
Congenital Epicanthus 3 | 175
Curvature of spine 3 | 275
Diarrhea 3 | 245
Glaucoma 3 | 232
Heart disease 3 | 288
Liver Dysfunction 3 | 97
Liver function tests abnormal finding 3 | 79
Skin cancer 3 | 451
active ulcerative colitis 3 | 736

Tissue

Endocrine System 89 | 18,159
Liver and Pancreas 89 | 16,750
Female tissues 88 | 17,400
Male tissues 88 | 17,142
Nervous System 88 | 16,725
Skin and soft tissues 88 | 17,230
Blood and immune system 87 | 16,909
Digestive Tract 87 | 17,369
Respiratory system 86 | 16,393
Urinary Tract 86 | 16,678
Cardiovascular System 83 | 15,192

Target Family

Enzyme 47 | 4,145
Non-IDG 27 | 12,091
Kinase 12 | 634
GPCR 2 | 408
Transporter 1 | 473

GO Process

cellular protein modification ... 89 | 89
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40659 32.1 99
Ubiquitin-conjugating enzyme E2 S UBE2S Tbio Non-IDG -2.36597 158.3 384
ERO1-like protein alpha ERO1A Tbio Non-IDG -1.54976 34.5 230
Tubulin--tyrosine ligase-like protein 12 TTLL12 Tbio Enzyme -0.67312 5.81 112
Lysosomal alpha-mannosidase MAN2B1 Tchem Enzyme -2.18158 152.9 35
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
Serine/threonine-protein kinase 38 STK38 Tbio Kinase -1.32086 23.2 359
Type 2 lactosamine alpha-2,3-sialyltransferase ST3GAL6 Tbio Enzyme -1.03998 9.43 40