Development Level

Tbio 140 | 11,445
Tchem 36 | 1,598
Tclin 11 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
preweaning lethality, complete... 6 | 979
abnormal seminal vesicle morph... 5 | 114
decreased bone mineral content 4 | 151
decreased vertical activity 4 | 208
increased fasted circulating g... 4 | 76
abnormal embryo size 3 | 220
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased circulating alkaline... 3 | 122
increased circulating triglyce... 3 | 42
short tibia 3 | 97
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal snout morphology 2 | 23
abnormal tooth morphology 2 | 24
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prolonged PR interval 2 | 15
small superior vagus ganglion 2 | 74
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal limb bud morphology 1 | 17
abnormal lip morphology 1 | 2
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal radius morphology 1 | 8
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
brachydactyly 1 | 19
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
pallor 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 126 | 11,493
ovarian cancer 113 | 8,520
psoriasis 96 | 6,694
lung cancer 85 | 4,740
osteosarcoma 80 | 7,950
glioblastoma 78 | 5,792
medulloblastoma, large-cell 70 | 6,241
Cancer 69 | 2,499
malignant mesothelioma 66 | 3,232
lung carcinoma 63 | 2,843
pancreatic cancer 62 | 2,398
atypical teratoid / rhabdoid tumor 61 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,955
Breast cancer 60 | 3,578
diabetes mellitus 58 | 1,728
non-small cell lung cancer 58 | 2,890
ependymoma 55 | 4,679
invasive ductal carcinoma 54 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,989
lung adenocarcinoma 52 | 2,716
Astrocytoma, Pilocytic 48 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,291
cystic fibrosis 42 | 1,696
ulcerative colitis 40 | 1,819
Autosomal recessive predisposition 38 | 1,442
adult high grade glioma 38 | 3,801
tuberculosis 37 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Kidney cancer 33 | 2,613
Kidney disease 33 | 430
group 3 medulloblastoma 33 | 4,104
interstitial cystitis 33 | 2,312
primary pancreatic ductal adenocarcinoma 33 | 1,109
primitive neuroectodermal tumor 33 | 3,035
adrenocortical carcinoma 32 | 1,428
juvenile dermatomyositis 32 | 1,187
pituitary cancer 32 | 1,972
breast carcinoma 31 | 1,638
ductal carcinoma in situ 31 | 1,745
Duchenne muscular dystrophy 30 | 601
oligodendroglioma 30 | 2,850
Atherosclerosis 29 | 291
Hypertension 29 | 396
Alzheimer's disease 28 | 658
Liver Cirrhosis, Experimental 28 | 769
subependymal giant cell astrocytoma 28 | 2,287
Schizophrenia 27 | 1,160
Coronary artery disease 25 | 268
Liver disease 25 | 237
Obesity 25 | 678
Rheumatoid arthritis 25 | 1,191
esophageal adenocarcinoma 25 | 737
colon cancer 24 | 1,478
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 510
gastric carcinoma 23 | 807
Arthritis 22 | 290
Hypertensive disease 22 | 292
Osteoporosis 22 | 363
active Crohn's disease 22 | 922
astrocytic glioma 22 | 2,597
group 4 medulloblastoma 22 | 1,855
pediatric high grade glioma 22 | 1,064
Amyloidosis 21 | 67
Endometriosis 21 | 540
Heart disease 21 | 306
dermatomyositis 21 | 966
astrocytoma 20 | 1,146
cutaneous lupus erythematosus 20 | 1,057
nasopharyngeal carcinoma 20 | 1,058
interstitial lung disease 19 | 298
Atopic dermatitis 18 | 952
Cerebrovascular disease 18 | 238
Dementia 18 | 175
Prostatic Neoplasms 18 | 495
active ulcerative colitis 18 | 764
acute quadriplegic myopathy 18 | 1,158
Chemical and Drug Induced Liver Injury 17 | 195
Down syndrome 17 | 499
Liver Cirrhosis 17 | 181
Lung disease 17 | 142
Melanoma 17 | 711
Neurodegenerative disease 17 | 414
Pick disease 17 | 1,894
Anemia 16 | 365
Bipolar Disorder 16 | 666
Vascular disease 16 | 319
Becker muscular dystrophy 15 | 191
Breast Neoplasms 15 | 445
Polycystic ovary syndrome 15 | 360
limb girdle muscular dystrophy 2A 15 | 213
Mammary Neoplasms 14 | 425
Multiple myeloma 14 | 1,332
Depressive disorder 13 | 409
Epilepsy 13 | 792
Lung Neoplasms 13 | 232
Short stature 13 | 531
Waldenstrons macroglobulinemia 13 | 765
fibroadenoma 13 | 559
nephrosclerosis 13 | 333
non primary Sjogren syndrome sicca 13 | 891

Tissue

Endocrine System 187 | 18,159
Digestive Tract 184 | 17,369
Female tissues 183 | 17,400
Liver and Pancreas 182 | 16,750
Male tissues 180 | 17,142
Skin and soft tissues 180 | 17,230
Urinary Tract 179 | 16,678
Blood and immune system 177 | 16,909
Respiratory system 172 | 16,393
Nervous System 170 | 16,725
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 141 | 12,091
Enzyme 44 | 4,145
Transporter 3 | 473
GPCR 2 | 408
Transcription Factor 2 | 1,400

GO Process

cellular protein metabolic pro... 192 | 192
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Palmitoyltransferase ZDHHC2 ZDHHC2 Tbio Enzyme -1.91418 79.6 82
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
Anoctamin-8 ANO8 Tbio Non-IDG -0.24444 1.60 13
Kinectin KTN1 Tbio Non-IDG -1.93411 83.4 89
Matrix remodeling-associated protein 8 MXRA8 Tdark Non-IDG -0.36209 1.25 8
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
N-acetyltransferase 8 NAT8 Tbio Enzyme -1.74418 54.5 143