Development Level

Tbio 11 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal pelvic girdle bone mo... 1 | 12
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 101
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small liver 1 | 8

Disease

Carcinoma 8 | 11,493
Cancer 7 | 2,499
lung cancer 7 | 4,740
ovarian cancer 6 | 8,520
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Kidney cancer 3 | 2,613
Lung Neoplasms 3 | 232
Rheumatoid arthritis 3 | 1,191
group 3 medulloblastoma 3 | 4,104
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
Abnormality of metabolism/homeostasis 2 | 134
Colonic Neoplasms 2 | 142
Multiple myeloma 2 | 1,332
Myocardial Infarction 2 | 151
Neurodegenerative disease 2 | 414
PARKINSON DISEASE 19, JUVENILE-ONSET 2 | 10
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Prostatic Neoplasms 2 | 495
Young onset Parkinson disease 2 | 10
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Adult onset 1 | 82
Alkaline phosphatase serum increased 1 | 29
Aortic aneurysm 1 | 38
Ataxia telangiectasia 1 | 34
Autistic Disorder 1 | 364
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Bradykinesia 1 | 34
Breast Neoplasms 1 | 445
Bronchioloalveolar Adenocarcinoma 1 | 14
Colorectal Neoplasms 1 | 243
DOID:2627 1 | 94
Dysgerminoma 1 | 11
Dystonia 1 | 164
Dystonic disease 1 | 106
Encephalopathy, progressive 1 | 6
Essential tremor 1 | 28
Familial encephalopathy with neuroserpin inclusion bodies 1 | 10
Gastrointestinal stromal tumor 1 | 62
Glioma 1 | 74
Gliosis in the substantia nigra 1 | 3
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Hirschsprung's disease 1 | 46
Increased risk of pancreatic cancer 1 | 9
Leprosy 1 | 73
Li-Fraumeni syndrome 1 | 13
Li-Fraumeni syndrome 2 1 | 2
Lymphoma 1 | 81
Lymphoma, Non-Hodgkin 1 | 24
Lytic lesion 1 | 32
Malignant neoplasm of pancreas 1 | 9
Malignant neoplasm of prostate 1 | 11
Malignant neoplasm of skin 1 | 15
Malignant tumor of prostate 1 | 26
Mammary Neoplasms 1 | 425
Manganese Poisoning 1 | 11
Memory Disorders 1 | 40
Meningioma 1 | 41
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Nerve Degeneration 1 | 121
Nervous System Neoplasms 1 | 8
Nijmegen breakage syndrome 1 | 24
Ophthalmomyiasis 1 | 3
Osteogenic Sarcoma 1 | 6
Ovarian Cysts 1 | 41
Ovarian Neoplasms 1 | 102
PARKINSON DISEASE, LATE-ONSET 1 | 20
Pain 1 | 103
Pancreatic Neuroendocrine Tumor 1 | 45
Parkinson Disease 1 | 64
Postural instability 1 | 19
Progressive brain disease 1 | 6
Pulmonary embolism 1 | 55
Renal Cell Carcinoma 1 | 214
Retinal Neoplasms 1 | 3
Retinoblastoma 1 | 19
Sarcoma 1 | 62
Skin Neoplasms 1 | 69
Stomach Carcinoma 1 | 11
Stomach cancer 1 | 30
Systemic lupus erythematosus 1 | 194
Tremor 1 | 113
Tumors of Adrenal Cortex 1 | 3
Type 1 diabetes mellitus 1 | 109
Usher syndrome type 3 1 | 5
Vitiligo 1 | 73
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 13 | 18,159
Female tissues 12 | 17,400
Nervous System 12 | 16,725
Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Kinase 2 | 634

GO Process

cellular protein catabolic pro... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.84360 6.17 155
Ras-related protein Rab-12 RAB12 Tbio Enzyme -1.21868 13.9 73
Melanoma-associated antigen 2 MAGEA2 Tbio Non-IDG -1.32923 19.6 34
Melanoma-associated antigen C2 MAGEC2 Tbio Non-IDG -2.02244 97.0 111
Ubiquitin-conjugating enzyme E2 G2 UBE2G2 Tbio Non-IDG -1.20607 15.4 270
DENN domain-containing protein 3 DENND3 Tbio Non-IDG -0.65079 3.95 23
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
E3 ubiquitin-protein ligase RNF5 RNF5 Tbio Enzyme -1.20054 15.1 166