Development Level

Tbio 52 | 11,651
Tchem 8 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal sleep behavior 2 | 70
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased mean corpuscular hem... 2 | 96
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
hydrometra 1 | 53
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
long tibia 1 | 25
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 38 | 11,493
ovarian cancer 36 | 8,520
osteosarcoma 28 | 7,950
psoriasis 26 | 6,694
Anemia 25 | 365
medulloblastoma, large-cell 25 | 6,241
Cancer 21 | 2,499
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
lung cancer 18 | 4,740
Breast cancer 15 | 3,578
Hemochromatosis 15 | 54
group 3 medulloblastoma 15 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
ependymoma 14 | 4,679
lung carcinoma 14 | 2,843
non-small cell lung cancer 14 | 2,890
Autosomal recessive predisposition 13 | 1,442
adult high grade glioma 12 | 3,801
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
malignant mesothelioma 12 | 3,232
pancreatic cancer 12 | 2,398
subependymal giant cell astrocytoma 12 | 2,287
primitive neuroectodermal tumor 11 | 3,035
Astrocytoma, Pilocytic 10 | 3,081
Multiple myeloma 10 | 1,332
Vascular disease 10 | 319
acute quadriplegic myopathy 10 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Aceruloplasminemia 9 | 16
adrenocortical carcinoma 9 | 1,428
diabetes mellitus 9 | 1,728
oligodendroglioma 9 | 2,850
pituitary cancer 9 | 1,972
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Alzheimer's disease 8 | 658
Atransferrinemia 8 | 8
Neurodegenerative disease 8 | 414
Parkinson's disease 8 | 392
Thalassemia 8 | 53
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Liver disease 7 | 237
Neoplasm Invasiveness 7 | 161
Obesity 7 | 678
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
Schizophrenia 7 | 1,160
Chemical and Drug Induced Liver Injury 6 | 195
Heart failure 6 | 162
Hyperferritinaemia 6 | 14
Increased ferritin 6 | 14
Iron deficiency anemia 6 | 12
Kidney disease 6 | 430
Liver Cirrhosis, Experimental 6 | 769
Serum ferritin increased 6 | 14
astrocytoma 6 | 1,146
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
primary pancreatic ductal adenocarcinoma 6 | 1,109
Arthritis, Rheumatoid 5 | 174
Friedreich ataxia 5 | 24
Hemoglobin low 5 | 124
Hypertension 5 | 396
Hypertensive disease 5 | 292
Inflammation 5 | 120
Iron Overload 5 | 5
Malaria 5 | 160
Parkinson Disease 5 | 64
Siderosis 5 | 9
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
interstitial cystitis 5 | 2,312
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Babinski Reflex 4 | 100
Contact Dermatitis 4 | 81
Depressive disorder 4 | 409
Dermatitis, Contact 4 | 71
Duchenne muscular dystrophy 4 | 601
Dysarthria 4 | 192
Liver carcinoma 4 | 240
Liver neoplasms 4 | 130
Peripheral vascular disease 4 | 87
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
mucosa-associated lymphoid tissue lymphoma 4 | 484
non diabetic and post-ischemic heart failure 4 | 200
progressive supranuclear palsy 4 | 676

Tissue

Endocrine System 61 | 18,159
Liver and Pancreas 60 | 16,750
Digestive Tract 59 | 17,369
Female tissues 59 | 17,400
Blood and immune system 58 | 16,909
Male tissues 58 | 17,142
Nervous System 58 | 16,725
Skin and soft tissues 58 | 17,230
Urinary Tract 58 | 16,678
Respiratory system 57 | 16,393
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 15 | 4,145
Transporter 9 | 473
Transcription Factor 3 | 1,400

GO Process

cellular iron ion homeostasis 62 | 62
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor coactivator 4 NCOA4 Tbio Non-IDG -2.20245 136.0 283
F-box/LRR-repeat protein 5 FBXL5 Tbio Non-IDG -1.25684 20.6 145
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
Cullin-associated NEDD8-dissociated protein 1 CAND1 Tbio Non-IDG -1.90448 77.8 173
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381
Scavenger receptor class A member 5 SCARA5 Tbio Non-IDG -1.39965 26.2 118
Tetratricopeptide repeat protein 7A TTC7A Tbio Non-IDG -1.44137 26.3 67
ATP-binding cassette sub-family G member 2 ABCG2 Tchem Transporter -3.41877 2731.1 246
Hemopexin HPX Tbio Non-IDG -2.85928 699.9 402
Humanin MT-RNR2 Tdark Non-IDG 0.00000 0