Development Level

Tbio 50 | 11,445
Tchem 17 | 1,598
Tclin 13 | 613
Tdark 5 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
decreased prepulse inhibition 3 | 82
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
abnormal behavior 2 | 298
decreased circulating sodium l... 2 | 22
enlarged uterus 2 | 11
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal iris morphology 1 | 13
abnormal iris transilluminatio... 1 | 2
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged thymus 1 | 5
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 52 | 11,493
ovarian cancer 44 | 8,520
psoriasis 44 | 6,694
glioblastoma 38 | 5,792
osteosarcoma 37 | 7,950
medulloblastoma, large-cell 36 | 6,241
adult high grade glioma 30 | 3,801
atypical teratoid / rhabdoid tumor 30 | 5,112
lung cancer 30 | 4,740
ependymoma 27 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
Cancer 23 | 2,499
lung carcinoma 23 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
group 3 medulloblastoma 21 | 4,104
Breast cancer 20 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Schizophrenia 19 | 1,160
malignant mesothelioma 19 | 3,232
Astrocytoma, Pilocytic 18 | 3,081
pancreatic cancer 18 | 2,398
interstitial cystitis 17 | 2,312
primitive neuroectodermal tumor 17 | 3,035
ulcerative colitis 17 | 1,819
astrocytic glioma 16 | 2,597
diabetes mellitus 16 | 1,728
invasive ductal carcinoma 16 | 2,951
oligodendroglioma 16 | 2,850
subependymal giant cell astrocytoma 16 | 2,287
Kidney cancer 15 | 2,613
lung adenocarcinoma 15 | 2,716
tuberculosis 15 | 2,010
Bipolar Disorder 14 | 666
Asthma 13 | 385
Autosomal recessive predisposition 13 | 1,442
colon cancer 13 | 1,478
juvenile dermatomyositis 13 | 1,187
non-small cell lung cancer 13 | 2,890
Arthritis 12 | 290
Hypertension 12 | 396
Kidney disease 12 | 430
adrenocortical carcinoma 12 | 1,428
Atherosclerosis 11 | 291
Heart disease 11 | 306
Hypertensive disease 11 | 292
Obesity 11 | 678
Seizures 11 | 596
pituitary cancer 11 | 1,972
Depressive disorder 10 | 409
Multiple Sclerosis 10 | 540
ductal carcinoma in situ 10 | 1,745
group 4 medulloblastoma 10 | 1,855
Coronary artery disease 9 | 268
Epilepsy 9 | 792
Hypersensitivity 9 | 63
Hypersensitivity reaction type II disease 9 | 253
Parkinson's disease 9 | 392
Pneumonia 9 | 174
breast carcinoma 9 | 1,638
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
dermatomyositis 9 | 966
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
sarcoidosis 9 | 370
Liver Cirrhosis, Experimental 8 | 769
Lung disease 8 | 142
Major Depressive Disorder 8 | 301
Mood Disorders 8 | 184
Multiple myeloma 8 | 1,332
Pick disease 8 | 1,894
Pulmonary Fibrosis 8 | 106
Waldenstrons macroglobulinemia 8 | 765
acute myeloid leukemia 8 | 783
nasopharyngeal carcinoma 8 | 1,058
non primary Sjogren syndrome sicca 8 | 891
primary pancreatic ductal adenocarcinoma 8 | 1,109
Atopic dermatitis 7 | 952
Attention deficit hyperactivity disorder 7 | 278
Autistic Disorder 7 | 364
Brain Ischemia 7 | 110
Melanoma 7 | 711
Myocardial Infarction 7 | 151
Skin cancer 7 | 469
Unipolar Depression 7 | 250
pancreatic carcinoma 7 | 562
Alzheimer's disease 6 | 658
Cerebrovascular disease 6 | 238
Dermatitis 6 | 157
Duchenne muscular dystrophy 6 | 601
Inflammatory bowel disease 6 | 151
Malaria 6 | 160
Mental Depression 6 | 333
Migraine 6 | 83
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Status Epilepticus 6 | 98
astrocytoma 6 | 1,146
fibroadenoma 6 | 559
gastric carcinoma 6 | 807
primary Sjogren syndrome 6 | 735

Tissue

Endocrine System 84 | 18,159
Female tissues 82 | 17,400
Male tissues 81 | 17,142
Digestive Tract 80 | 17,369
Skin and soft tissues 80 | 17,230
Liver and Pancreas 79 | 16,750
Blood and immune system 78 | 16,909
Respiratory system 75 | 16,393
Urinary Tract 75 | 16,678
Nervous System 74 | 16,725
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 42 | 12,091
Transporter 17 | 473
GPCR 11 | 408
Ion Channel 6 | 344
Enzyme 4 | 4,145
Kinase 3 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

cellular calcium ion homeostas... 85 | 85
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc transporter 1 SLC30A1 Tbio Transporter -2.12639 135.9 148
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258