Development Level

Tbio 23 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
brachydactyly 1 | 19
cystolithiasis 1 | 3
decreased bone mineral density 1 | 126
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased effector memory CD4-... 1 | 1
polycystic kidney 1 | 15
small kidney 1 | 16
syndactyly 1 | 23

Disease

Carcinoma 18 | 11,493
Autosomal recessive predisposition 11 | 1,442
lung cancer 11 | 4,740
ovarian cancer 11 | 8,520
osteosarcoma 10 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
diabetes mellitus 8 | 1,728
glioblastoma 8 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
psoriasis 8 | 6,694
Cancer 7 | 2,499
Cognitive delay 7 | 608
Epilepsy 7 | 792
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Seizures 7 | 596
lung carcinoma 7 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Lysinuric protein intolerance 6 | 15
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
Schizophrenia 5 | 1,160
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Anemia 4 | 365
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Infantile onset 4 | 238
Intellectual disability 4 | 1,016
Major Depressive Disorder 4 | 301
Muscle hypotonia 4 | 571
Obesity 4 | 678
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Blepharoptosis 3 | 231
Cerebral atrophy 3 | 178
Choreoathetoid movements 3 | 32
Choreoathetosis 3 | 32
Degenerative brain disorder 3 | 100
Deglutition Disorders 3 | 132
Dull intelligence 3 | 645
Dystonia 3 | 164
Failure to gain weight 3 | 365
Hepatomegaly 3 | 285
Hypertension 3 | 396
Irritation - emotion 3 | 68
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle Weakness 3 | 170
Myoclonus 3 | 74
Parkinsonian Disorders 3 | 56
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Progressive neurologic deterioration 3 | 19
Retinitis Pigmentosa 3 | 226
Small head 3 | 374
Splenomegaly 3 | 190
Supratentorial atrophy 3 | 94
Thrombocytopenia 3 | 197
Unipolar Depression 3 | 250
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Atherosclerosis 2 | 291
Cerebrovascular disease 2 | 238
Concave bridge of nose 2 | 195
Coronary artery disease 2 | 268
Depressed nasal root/bridge 2 | 195
Heart disease 2 | 306
Hemoglobin low 2 | 124
Kidney disease 2 | 430
Lung Neoplasms 2 | 232
Nephrolithiasis 2 | 56
Psychotic Disorders 2 | 151
Stomach Neoplasms 2 | 300
atypical teratoid/rhabdoid tumor 2 | 357
medulloblastoma 2 | 720

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Nervous System 27 | 16,725
Cardiovascular System 25 | 15,192

Target Family

Enzyme 16 | 4,145
Transporter 9 | 473
Non-IDG 2 | 12,091
Transcription Factor 1 | 1,400

GO Process

cellular amino acid metabolic ... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.55868 37.6 57
N-fatty-acyl-amino acid synthase/hydrolase PM20D1 PM20D1 Tdark Enzyme -0.67745 3.43 23
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Kynurenine--oxoglutarate transaminase 3 KYAT3 Tbio Enzyme -0.86445 6.75 59
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 Tchem Transporter -1.42715 25.8 76
Cationic amino acid transporter 4 SLC7A4 Tbio Transporter -1.89963 73.3 62
Y+L amino acid transporter 2 SLC7A6 Tbio Transporter -1.48428 28.6 64