Development Level

Tbio 57 | 10,625
Tchem 17 | 1,890
Tdark 8 | 7,003
Tclin 7 | 602

IMPC Term

preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal startle reflex 1 | 14
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased eosinophil cell numb... 1 | 41
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
head bobbing 1 | 3
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral density 1 | 52
increased circulating free fat... 1 | 17
increased hematocrit 1 | 36
increased leukocyte cell numbe... 1 | 37
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased vertical activity 1 | 18
preweaning lethality, complete... 1 | 633
tremors 1 | 34

Disease

ovarian cancer 52 | 8,492
osteosarcoma 41 | 7,933
glioblastoma 38 | 5,572
psoriasis 38 | 6,685
Cancer 32 | 2,346
non-small cell lung cancer 32 | 2,798
invasive ductal carcinoma 29 | 2,950
lung cancer 29 | 4,473
medulloblastoma, large-cell 29 | 6,234
pancreatic cancer 29 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
pilocytic astrocytoma 27 | 3,086
atypical teratoid / rhabdoid tumor 26 | 4,369
lung carcinoma 26 | 2,844
malignant mesothelioma 26 | 3,163
pediatric high grade glioma 25 | 2,712
Carcinoma 24 | 2,147
interstitial cystitis 24 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
Breast cancer 22 | 3,099
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
lung adenocarcinoma 22 | 2,714
cystic fibrosis 21 | 1,670
ependymoma 20 | 2,514
ductal carcinoma in situ 18 | 1,745
pituitary cancer 18 | 1,972
primary pancreatic ductal adenocarcinoma 18 | 1,271
tuberculosis 18 | 1,563
ulcerative colitis 17 | 2,087
colon cancer 14 | 1,475
diabetes mellitus 14 | 1,663
group 3 medulloblastoma 14 | 2,254
Duchenne muscular dystrophy 13 | 602
Pick disease 13 | 1,893
breast carcinoma 13 | 1,614
oligodendroglioma 13 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
primitive neuroectodermal tumor 13 | 3,031
subependymal giant cell astrocytoma 13 | 2,287
astrocytoma 12 | 1,493
cutaneous lupus erythematosus 12 | 1,056
gastric carcinoma 12 | 832
posterior fossa group A ependymoma 12 | 1,511
sonic hedgehog group medulloblastoma 12 | 1,482
Atopic dermatitis 11 | 944
adrenocortical carcinoma 11 | 1,427
dermatomyositis 11 | 967
Kidney disease 10 | 397
astrocytic glioma 10 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
Atherosclerosis 9 | 275
Rheumatoid Arthritis 9 | 1,171
group 4 medulloblastoma 9 | 1,875
juvenile dermatomyositis 9 | 1,189
nasopharyngeal carcinoma 9 | 1,056
Cerebrovascular disease 8 | 231
medulloblastoma 8 | 1,524
primary Sjogren syndrome 8 | 789
Arthritis 7 | 248
IGA Glomerulonephritis 7 | 454
acute quadriplegic myopathy 7 | 1,157
adult high grade glioma 7 | 2,148
aldosterone-producing adenoma 7 | 664
esophageal adenocarcinoma 7 | 737
mucosa-associated lymphoid tissue lymphoma 7 | 480
nephrosclerosis 7 | 329
Alzheimer's disease 6 | 644
Coronary artery disease 6 | 240
Down syndrome 6 | 548
Gliosis 6 | 16
Heart disease 6 | 279
Prostatic Neoplasms 6 | 471
fibroadenoma 6 | 557
head and neck cancer 6 | 270
pancreatic carcinoma 6 | 567
Becker muscular dystrophy 5 | 187
Epidermolysis bullosa 5 | 21
Hypertension 5 | 293
Inflammatory bowel disease 5 | 142
Multiple Sclerosis 5 | 498
Neoplasm Metastasis 5 | 138
Osteoporosis 5 | 259
Spontaneous abortion 5 | 108
Thrombocytopenia 5 | 105
Vascular disease 5 | 281
non-inflammatory breast cancer 5 | 208
non-small cell lung carcinoma 5 | 413
Crohn's disease 4 | 304
Hypersensitivity reaction type II disease 4 | 235
Liver carcinoma 4 | 217
Nonsyndromic deafness 4 | 121
Schizophrenia 4 | 503
Stomach Neoplasms 4 | 282
Thrombophilia 4 | 37
active Crohn's disease 4 | 918
gastric cancer 4 | 436
glioblastoma multiforme 4 | 347
non diabetic and post-ischemic heart failure 4 | 200
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064

Tissue

Digestive Tract 88 | 18,473
Endocrine System 88 | 18,512
Female tissues 88 | 18,647
Urinary Tract 88 | 18,444
Blood and immune system 87 | 17,995
Cardiovascular System 87 | 17,958
Liver and Pancreas 87 | 18,136
Male tissues 87 | 17,969
Nervous System 87 | 18,561
Respiratory system 87 | 17,484
Skin and soft tissues 87 | 18,115

Target Family

Non-IDG 77 | 11,969
Enzyme 7 | 4,146
Transcription Factor 3 | 1,400
Kinase 2 | 634

GO Process

cell-matrix adhesion 89 | 89
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-defensin 118 DEFB118 Tdark Non-IDG -0.54407 3.57 6
Mucosal addressin cell adhesion molecule 1 MADCAM1 Tbio Non-IDG -2.35862 237.7 327
Gamma-parvin PARVG Tchem Non-IDG -0.72411 5.81 64
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.03866 113.6 184
Mesothelin MSLN Tchem Non-IDG -2.62612 422.1 457
Integrin-linked protein kinase ILK Tchem Kinase -2.73086 643.3 578
Paxillin PXN Tchem Non-IDG -2.97313 849.9 1088
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tchem Enzyme -1.86857 82.1 230
Integrin beta-7 ITGB7 Tclin Non-IDG -1.61222 35.4 310
Transmembrane protein 8B TMEM8B Tbio Non-IDG -1.32225 24.4 97