Development Level

Tbio 201 | 11,651
Tdark 45 | 6,593
Tclin 31 | 612
Tchem 23 | 1,388

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased lean body mass 7 | 135
increased total body fat amoun... 7 | 134
enlarged heart 6 | 210
decreased bone mineral content 5 | 151
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
hypoactivity 4 | 132
increased bone mineral content 4 | 108
increased startle reflex 4 | 112
abnormal behavior 3 | 298
abnormal heart morphology 3 | 162
abnormal sleep behavior 3 | 70
abnormal tail morphology 3 | 25
decreased body length 3 | 101
decreased body weight 3 | 161
decreased circulating insulin ... 3 | 76
decreased fasted circulating g... 3 | 65
decreased neutrophil cell numb... 3 | 42
improved glucose tolerance 3 | 79
increased circulating alkaline... 3 | 122
abnormal behavioral response t... 2 | 66
abnormal body wall morphology 2 | 9
abnormal bone mineralization 2 | 38
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
cleft palate 2 | 8
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased circulating amylase ... 2 | 28
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased total body fat amoun... 2 | 207
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased bone mineral density 2 | 72
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
mammalian phenotype 2 | 17
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 161 | 11,493
psoriasis 143 | 6,694
Cancer 115 | 2,499
osteosarcoma 107 | 7,950
lung cancer 105 | 4,740
ovarian cancer 104 | 8,520
glioblastoma 97 | 5,792
adult high grade glioma 77 | 3,801
malignant mesothelioma 77 | 3,232
medulloblastoma, large-cell 76 | 6,241
interstitial cystitis 75 | 2,312
ependymoma 74 | 4,679
Breast cancer 72 | 3,578
atypical teratoid / rhabdoid tumor 71 | 5,112
lung carcinoma 70 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
Astrocytoma, Pilocytic 62 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 59 | 3,291
lung adenocarcinoma 59 | 2,716
invasive ductal carcinoma 58 | 2,951
pancreatic cancer 58 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
non-small cell lung cancer 56 | 2,890
Kidney cancer 54 | 2,613
diabetes mellitus 54 | 1,728
tuberculosis 53 | 2,010
ulcerative colitis 53 | 1,819
group 3 medulloblastoma 52 | 4,104
oligodendroglioma 51 | 2,850
cutaneous lupus erythematosus 49 | 1,057
cystic fibrosis 45 | 1,696
astrocytic glioma 44 | 2,597
primitive neuroectodermal tumor 43 | 3,035
Schizophrenia 42 | 1,160
Asthma 41 | 385
pituitary cancer 41 | 1,972
Rheumatoid arthritis 40 | 1,191
breast carcinoma 40 | 1,638
Obesity 39 | 678
Autosomal recessive predisposition 35 | 1,442
colon cancer 35 | 1,478
Multiple Sclerosis 34 | 540
subependymal giant cell astrocytoma 34 | 2,287
Hypertension 30 | 396
ductal carcinoma in situ 30 | 1,745
Liver Cirrhosis, Experimental 28 | 769
Arthritis 26 | 290
Bipolar Disorder 26 | 666
Endometriosis 26 | 540
active Crohn's disease 26 | 922
Atopic dermatitis 25 | 952
gastric carcinoma 25 | 807
primary pancreatic ductal adenocarcinoma 25 | 1,109
juvenile dermatomyositis 24 | 1,187
nasopharyngeal carcinoma 24 | 1,058
Hypersensitivity reaction type II disease 23 | 253
Kidney disease 23 | 430
adrenocortical carcinoma 23 | 1,428
non primary Sjogren syndrome sicca 23 | 891
Down syndrome 21 | 499
Lung disease 21 | 142
Major Depressive Disorder 21 | 301
Parkinson's disease 21 | 392
Seizures 21 | 596
active ulcerative colitis 21 | 764
group 4 medulloblastoma 21 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Atherosclerosis 20 | 291
Epilepsy 20 | 792
Inflammatory bowel disease 20 | 151
Melanoma 20 | 711
spina bifida 20 | 1,074
Adenoma 19 | 167
Breast Neoplasms 19 | 445
Depressive disorder 19 | 409
Dermatitis 19 | 157
Hypertensive disease 19 | 292
Intellectual disability 19 | 1,016
Mammary Neoplasms 19 | 425
Mental Depression 19 | 333
Pneumonia 19 | 174
Short stature 19 | 531
Unipolar Depression 19 | 250
Allergic hypersensitivity disease 18 | 126
Autistic Disorder 18 | 364
Coronary artery disease 18 | 268
Heart disease 18 | 306
Hypogonadism 18 | 173
Osteoporosis 18 | 363
Pick disease 18 | 1,894
esophageal adenocarcinoma 18 | 737
head and neck cancer and chronic obstructive pulmonary disease 18 | 239
Alcoholic Intoxication, Chronic 17 | 289
Cerebrovascular disease 17 | 238
Glaucoma 17 | 239
astrocytoma 17 | 1,146
Alzheimer's disease 16 | 658
Polycystic ovary syndrome 16 | 360
Vascular disease 16 | 319
aldosterone-producing adenoma 16 | 665

Tissue

Endocrine System 289 | 18,159
Digestive Tract 279 | 17,369
Female tissues 276 | 17,400
Skin and soft tissues 271 | 17,230
Liver and Pancreas 269 | 16,750
Blood and immune system 263 | 16,909
Male tissues 263 | 17,142
Urinary Tract 263 | 16,678
Nervous System 258 | 16,725
Respiratory system 253 | 16,393
Cardiovascular System 209 | 15,192

Target Family

Non-IDG 231 | 12,091
GPCR 24 | 408
Enzyme 23 | 4,145
Transcription Factor 8 | 1,400
Kinase 5 | 634
Ion Channel 4 | 344
Nuclear Receptor 4 | 48
Epigenetic 1 | 242

GO Process

cell-cell signaling 300 | 300
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Putative peptide YY-2 PYY2 Tdark Non-IDG 0.00000 0
Choriogonadotropin subunit beta variant 1 CGB1 Tdark Non-IDG -0.23045 0.00000 12
Agouti-signaling protein ASIP Tbio Non-IDG -1.78281 57.2 34
C-C motif chemokine 27 CCL27 Tbio Non-IDG -2.72180 519.6 214
Diphosphoinositol polyphosphate phosphohydrolase 1 NUDT3 Tbio Enzyme -2.01736 105.3 40
Thyrotropin-releasing hormone-degrading ectoenzyme TRHDE Tbio Enzyme -1.62910 39.1 51
C-X-C motif chemokine 5 CXCL5 Tbio Non-IDG -2.44551 266.4 370
Protocadherin alpha-10 PCDHA10 Tdark Non-IDG 0.60 0.33 122