Development Level

Tbio 168 | 10,625
Tchem 39 | 1,890
Tclin 31 | 602
Tdark 11 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 8 | 633
enlarged heart 5 | 111
abnormal bone structure 4 | 131
abnormal embryo size 4 | 112
abnormal heart morphology 3 | 51
abnormal tail morphology 3 | 17
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
decreased monocyte cell number 3 | 28
embryonic lethality prior to t... 3 | 187
improved glucose tolerance 3 | 56
abnormal body wall morphology 2 | 7
abnormal bone mineralization 2 | 55
abnormal coat appearance 2 | 25
cleft palate 2 | 6
decreased circulating alkaline... 2 | 41
decreased circulating calcium ... 2 | 33
decreased circulating insulin ... 2 | 75
decreased fasted circulating g... 2 | 49
impaired righting response 2 | 19
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased mean corpuscular vol... 2 | 91
limb grasping 2 | 35
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal body size 1 | 1
abnormal brain morphology 1 | 6
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal facial morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal posture 1 | 5
abnormal radius morphology 1 | 8
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
hydroencephaly 1 | 6
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
kinked tail 1 | 3
oligodactyly 1 | 14
pale yolk sac 1 | 12
prolonged PR interval 1 | 4
short tail 1 | 4
shortened RR interval 1 | 19
small testis 1 | 37
thick tail 1 | 1

Disease

psoriasis 123 | 6,685
Cancer 111 | 2,346
ovarian cancer 96 | 8,484
osteosarcoma 94 | 7,933
lung cancer 90 | 4,466
glioblastoma 82 | 5,572
interstitial cystitis 73 | 2,299
medulloblastoma, large-cell 67 | 6,234
lung carcinoma 64 | 2,844
malignant mesothelioma 62 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,956
pilocytic astrocytoma 56 | 3,086
Breast cancer 55 | 3,094
invasive ductal carcinoma 55 | 2,950
lung adenocarcinoma 55 | 2,713
ulcerative colitis 55 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,988
atypical teratoid / rhabdoid tumor 51 | 4,369
non-small cell lung cancer 50 | 2,798
pancreatic cancer 50 | 2,300
diabetes mellitus 49 | 1,663
cutaneous lupus erythematosus 47 | 1,056
oligodendroglioma 45 | 2,849
adult high grade glioma 44 | 2,148
Asthma 40 | 349
cystic fibrosis 39 | 1,665
pediatric high grade glioma 39 | 2,712
pituitary cancer 39 | 1,972
tuberculosis 39 | 1,557
primitive neuroectodermal tumor 38 | 3,031
breast carcinoma 37 | 1,614
posterior fossa group A ependymoma 37 | 1,511
Rheumatoid Arthritis 36 | 1,160
colon cancer 34 | 1,475
Obesity 31 | 616
astrocytic glioma 30 | 2,241
Multiple Sclerosis 29 | 498
subependymal giant cell astrocytoma 29 | 2,287
group 4 medulloblastoma 27 | 1,875
Arthritis 26 | 248
ductal carcinoma in situ 26 | 1,745
Atopic dermatitis 25 | 944
Carcinoma 25 | 2,147
group 3 medulloblastoma 25 | 2,254
active Crohn's disease 24 | 918
gastric carcinoma 24 | 832
nasopharyngeal carcinoma 24 | 1,056
primary pancreatic ductal adenocarcinoma 24 | 1,271
Hypersensitivity reaction type II disease 23 | 235
Hypertension 23 | 287
ependymoma 23 | 2,514
Endometriosis 22 | 535
Lung disease 21 | 132
adrenocortical carcinoma 21 | 1,427
juvenile dermatomyositis 21 | 1,189
Kidney disease 20 | 396
Parkinson's disease 20 | 364
astrocytoma 20 | 1,493
spina bifida 20 | 1,064
Adenoma 19 | 165
Atherosclerosis 19 | 275
Allergic hypersensitivity disease 18 | 123
Down syndrome 18 | 548
Pneumonia 18 | 133
posterior fossa group B ependymoma 18 | 1,530
primary Sjogren syndrome 18 | 789
Cerebrovascular disease 17 | 231
Heart disease 17 | 279
Inflammatory bowel disease 17 | 142
Mammary Neoplasms 17 | 410
medulloblastoma 17 | 1,524
non primary Sjogren syndrome sicca 17 | 840
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
Coronary artery disease 16 | 240
Dermatitis 16 | 107
Hypersensitivity 16 | 63
head and neck cancer and chronic obstructive pulmonary disease 16 | 237
sarcoidosis 16 | 358
sonic hedgehog group medulloblastoma 16 | 1,482
Allergic rhinitis 15 | 91
Alzheimer's disease 15 | 644
Autistic Disorder 15 | 320
Hypertensive disease 15 | 193
Prostatic Neoplasms 15 | 471
Schizophrenia 15 | 501
aldosterone-producing adenoma 15 | 664
esophageal adenocarcinoma 15 | 737
Common cold 14 | 63
Eosinophilia 14 | 65
Hypogonadism 14 | 70
Influenza 14 | 142
Pick disease 14 | 1,893
Vascular disease 14 | 281
fibroadenoma 14 | 557
hepatocellular carcinoma 14 | 532
Anemia 13 | 252
Hypotension 13 | 53
active ulcerative colitis 13 | 477
head and neck cancer 13 | 270

Tissue

Nervous System 237 | 18,561
Digestive Tract 235 | 18,473
Female tissues 235 | 18,647
Endocrine System 233 | 18,512
Skin and soft tissues 231 | 18,115
Urinary Tract 231 | 18,444
Liver and Pancreas 227 | 18,136
Blood and immune system 226 | 17,995
Cardiovascular System 223 | 17,958
Male tissues 220 | 17,969
Respiratory system 214 | 17,484

Target Family

Non-IDG 179 | 11,971
GPCR 24 | 406
Enzyme 20 | 4,146
Transcription Factor 8 | 1,400
Kinase 5 | 634
oGPCR 5 | 421
Nuclear Receptor 4 | 48
Ion Channel 3 | 341
Epigenetic 1 | 242

GO Process

cell-cell signaling 249 | 249
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Class A basic helix-loop-helix protein 15 BHLHA15 Tbio Transcription Factor -1.24086 19.1 70
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.00731 99.9 143
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321
Lymphotoxin-alpha LTA Tbio Non-IDG -2.84770 612.8 461
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.77228 625.6 162