Development Level

Tbio 14 | 10,625
Tchem 2 | 1,890
Tclin 2 | 602

IMPC Term

preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal pericardium morpholog... 1 | 11
abnormal sleep behavior 1 | 63
cardiovascular system phenotyp... 1 | 35
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 79
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating triglyce... 1 | 24
increased hematocrit 1 | 36
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107

Disease

osteosarcoma 9 | 7,933
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung cancer 8 | 4,466
Carcinoma 7 | 2,147
glioblastoma 7 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
invasive ductal carcinoma 7 | 2,950
medulloblastoma, large-cell 7 | 6,234
psoriasis 7 | 6,685
atypical teratoid / rhabdoid tumor 6 | 4,369
lung adenocarcinoma 6 | 2,713
malignant mesothelioma 6 | 3,162
ovarian cancer 6 | 8,484
pediatric high grade glioma 6 | 2,712
Cancer 5 | 2,346
ependymoma 5 | 2,514
non-small cell lung cancer 5 | 2,798
astrocytic glioma 4 | 2,241
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,875
pilocytic astrocytoma 4 | 3,086
primitive neuroectodermal tumor 4 | 3,031
ulcerative colitis 4 | 2,087
urothelial carcinoma 4 | 318
Breast cancer 3 | 3,094
Diabetic Retinopathy 3 | 53
Multiple Sclerosis 3 | 498
Pick disease 3 | 1,893
juvenile dermatomyositis 3 | 1,189
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
oligodendroglioma 3 | 2,849
pituitary cancer 3 | 1,972
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Birt-Hogg-Dube syndrome 2 | 10
Brain edema 2 | 26
Cerebrovascular disease 2 | 231
Cholestasis 2 | 93
Colorectal Neoplasms 2 | 217
Down syndrome 2 | 548
Hypertension 2 | 287
Hypertensive disease 2 | 193
Liver neoplasms 2 | 109
Neurodegenerative disease 2 | 383
Oculodentodigital dysplasia 2 | 14
Ovarian hyperstimulation syndrome 2 | 15
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 933
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
nephrosclerosis 2 | 329
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
Arrhythmogenic right ventricular cardiomyopathy 1 | 27
Bipolar Disorder 1 | 266
COPD 1 | 113
Calculus in biliary tract 1 | 2
Celiac disease 1 | 112
Charcot-Marie-Tooth disease 1 | 74
Cholelithiasis Prevention 1 | 1
Cholestasis of pregnancy 1 | 5
Colon Carcinoma 1 | 25
Corneal edema 1 | 14
Dentin sensitivity 1 | 14
Drug-Induced Liver Injury 1 | 118
Epidermolysis bullosa 1 | 21
Extravasation of Diagnostic and Therapeutic Materials 1 | 6
Fatty liver disease 1 | 84
Intestinal Neoplasms 1 | 11
Intrahepatic cholestasis 1 | 19
Irritable bowel syndrome 1 | 59
Leber congenital amaurosis 1 | 72
Leukocyte adhesion deficiency 1 | 15
Liver disease 1 | 219
Liver diseases 1 | 66
Mammary Neoplasms 1 | 410
Muscular atrophy 1 | 67
Neoplasm Invasiveness 1 | 127
Neoplastic Syndromes, Hereditary 1 | 48
Osteoporosis 1 | 257
Peeling skin syndrome 1 | 16
Polycystic kidney disease 1 | 54
Primary cholangitis 1 | 2
Renal Cell Carcinoma 1 | 199
Retinal Degeneration 1 | 49
Sclerosing cholangitis 1 | 16
interstitial lung disease 1 | 291
non-inflammatory breast cancer 1 | 208

Tissue

Blood and immune system 18 | 17,995
Digestive Tract 18 | 18,473
Endocrine System 18 | 18,512
Female tissues 18 | 18,647
Liver and Pancreas 18 | 18,136
Nervous System 18 | 18,561
Respiratory system 18 | 17,484
Skin and soft tissues 18 | 18,115
Urinary Tract 18 | 18,444
Cardiovascular System 17 | 17,958
Male tissues 17 | 17,969

Target Family

Non-IDG 15 | 11,971
Epigenetic 1 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

GO Process

cell-cell junction assembly 18 | 18
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gap junction gamma-1 protein GJC1 Tbio Non-IDG -2.26749 174.8 192
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.22681 169.2 210
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.48530 306.4 272
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.05111 120.6 7
Talin-2 TLN2 Tbio Non-IDG -1.30281 18.3 45
Talin-1 TLN1 Tbio Non-IDG -1.84855 80.4 340
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.77781 670.1 248
Histone deacetylase 7 HDAC7 Tclin Epigenetic -1.96782 100.3 421
Partitioning defective 6 homolog beta PARD6B Tbio Non-IDG -0.78485 5.86 101
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.14176 1243.9 230