Development Level

Tbio 8 | 10,625
Tchem 2 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal behavior 1 | 226
decreased bone mineral content 1 | 157
decreased grip strength 1 | 123
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating alkaline... 1 | 119
increased circulating total pr... 1 | 20

Disease

osteosarcoma 5 | 7,933
ovarian cancer 5 | 8,484
ependymoma 4 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
primary pancreatic ductal adenocarcinoma 4 | 1,271
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,713
malignant mesothelioma 3 | 3,162
medulloblastoma, large-cell 3 | 6,234
oligodendroglioma 3 | 2,849
psoriasis 3 | 6,685
Cancer 2 | 2,346
Hypertension 2 | 287
Hypertensive disease 2 | 193
Pain 2 | 70
Pseudohypoaldosteronism 2 | 22
Rheumatoid Arthritis 2 | 1,160
Schnyder corneal dystrophy 2 | 23
Sickle cell anemia 2 | 35
Vascular disease 2 | 281
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
atypical teratoid / rhabdoid tumor 2 | 4,369
gastric carcinoma 2 | 832
glioblastoma 2 | 5,572
interstitial cystitis 2 | 2,299
lung cancer 2 | 4,466
non-inflammatory breast cancer 2 | 208
pancreatic cancer 2 | 2,300
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Adenoid Cystic Carcinoma 1 | 99
Agammaglobulinemia 1 | 24
Amyotrophic Lateral Sclerosis 1 | 431
Animal Mammary Neoplasms 1 | 136
Benign familial infantile epilepsy 1 | 2
Bladder Neoplasm 1 | 109
Bone Diseases 1 | 8
Bone disease 1 | 6
Brain edema 1 | 26
Cardiovascular system disease 1 | 194
Charcot-Marie-Tooth disease 1 | 74
Chronic Lymphocytic Leukemia 1 | 242
Chronic Obstructive Airway Disease 1 | 47
Congenital hemolytic anemia 1 | 30
Congestive heart failure 1 | 30
Degenerative polyarthritis 1 | 93
Dentin sensitivity 1 | 14
Down syndrome 1 | 548
Edema, Cardiac 1 | 2
Epidermodysplasia verruciformis 1 | 21
Essential Hypertension 1 | 82
Hydrarthrosis 1 | 2
Hydrocephalus 1 | 60
Hyperalgesia 1 | 71
Hypertensive disorder 1 | 58
Hyperthyroidism 1 | 50
Hyponatremia 1 | 6
Kidney disease 1 | 396
Liver carcinoma 1 | 217
Malignant neoplasm of breast 1 | 63
Mammary Neoplasms, Experimental 1 | 150
Melanoma 1 | 261
Meniere's disease 1 | 24
Metatropic dwarfism 1 | 1
Muscular atrophy 1 | 67
Neurodegenerative disease 1 | 383
Neuromuscular Diseases 1 | 3
Neuromyelitis optica 1 | 20
Neuronal ceroid lipofuscinosis 1 | 28
Neuropathy 1 | 210
Oligohydramnios 1 | 18
Osteochondrodysplasias 1 | 15
Pityriasis versicolor 1 | 18
Polycystic kidney disease 1 | 54
Polyhydramnios 1 | 29
Pulmonary edema 1 | 14
Renal tubular acidosis 1 | 14
Salivary Gland Neoplasms 1 | 45
Septic Shock 1 | 5
Spinal muscular atrophy 1 | 24
Spondylometaphyseal dysplasia, Kozlowski type 1 | 2
Syringomyelia 1 | 9
Tinea corporis 1 | 25
Tinea cruris 1 | 12
Tinea pedis 1 | 30
Ureteral disease 1 | 23
Urination Disorders 1 | 4
Waldenstrons macroglobulinemia 1 | 765
astrocytoma 1 | 1,493
breast carcinoma 1 | 1,614
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
glioblastoma multiforme 1 | 347
interstitial lung disease 1 | 291
mucosa-associated lymphoid tissue lymphoma 1 | 480
pterygium 1 | 74
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Ion Channel 3 | 341
Non-IDG 3 | 11,971
Transporter 2 | 473
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

GO Process

cell volume homeostasis 10 | 10
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chloride transport protein 6 CLCN6 Tbio Ion Channel -1.28791 18.7 67
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.38460 284.0 184
Volume-regulated anion channel subunit LRRC8A LRRC8A Tbio Non-IDG -1.35971 30.0 111
Aquaporin-1 AQP1 Tbio Non-IDG -3.04203 1040.5 321
Solute carrier family 12 member 4 SLC12A4 Tbio Transporter -1.64580 43.7 99
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.77781 670.1 248
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.41549 25.5 130
Transcription factor E2F4 E2F4 Tbio Transcription Factor -2.29006 183.7 248
Alpha-adducin ADD1 Tbio Enzyme -2.42657 275.9 522
Methylosome subunit pICln CLNS1A Tbio Non-IDG -1.69210 51.6 120