Development Level

Tbio 143 | 11,651
Tchem 40 | 1,388
Tclin 38 | 612
Tdark 18 | 6,593

Collection

RFA-RM-18-021 20 | 328
GPCR: IDG Consortium (Targets) 19 | 126
GPCR: IDG Consortium (Complete... 7 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased bone mineral content 7 | 151
decreased lean body mass 7 | 135
preweaning lethality, incomple... 7 | 499
abnormal behavior 6 | 298
decreased vertical activity 6 | 208
decreased bone mineral density 5 | 126
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
prolonged QT interval 4 | 38
abnormal bone structure 3 | 187
decreased heart weight 3 | 27
enlarged heart 3 | 210
improved glucose tolerance 3 | 79
increased circulating iron lev... 3 | 30
increased startle reflex 3 | 112
thrombocytopenia 3 | 56
abnormal QT variability 2 | 10
abnormal embryo size 2 | 220
abnormal eye anterior chamber ... 2 | 9
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased circulating amylase ... 2 | 28
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
prolonged QRS complex duration 2 | 8
prolonged ST segment 2 | 36
short tibia 2 | 97
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58
trunk curl 1 | 16

Disease

Carcinoma 150 | 11,493
psoriasis 113 | 6,694
osteosarcoma 112 | 7,950
ovarian cancer 108 | 8,520
lung cancer 92 | 4,740
glioblastoma 90 | 5,792
lung carcinoma 84 | 2,843
Cancer 82 | 2,499
medulloblastoma, large-cell 78 | 6,241
interstitial cystitis 72 | 2,312
adult high grade glioma 66 | 3,801
ependymoma 66 | 4,679
atypical teratoid / rhabdoid tumor 65 | 5,112
lung adenocarcinoma 64 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
non-small cell lung cancer 63 | 2,890
cutaneous lupus erythematosus 55 | 1,057
tuberculosis 55 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,955
ulcerative colitis 54 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,989
malignant mesothelioma 53 | 3,232
Astrocytoma, Pilocytic 51 | 3,081
Breast cancer 50 | 3,578
invasive ductal carcinoma 50 | 2,951
group 3 medulloblastoma 48 | 4,104
pancreatic cancer 48 | 2,398
Autosomal recessive predisposition 44 | 1,442
diabetes mellitus 41 | 1,728
Kidney cancer 38 | 2,613
Rheumatoid arthritis 37 | 1,191
breast carcinoma 37 | 1,638
colon cancer 37 | 1,478
ductal carcinoma in situ 37 | 1,745
subependymal giant cell astrocytoma 37 | 2,287
pituitary cancer 36 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
oligodendroglioma 33 | 2,850
Schizophrenia 32 | 1,160
cystic fibrosis 29 | 1,696
primitive neuroectodermal tumor 29 | 3,035
Hypertension 26 | 396
Multiple Sclerosis 26 | 540
juvenile dermatomyositis 24 | 1,187
mucosa-associated lymphoid tissue lymphoma 24 | 484
Liver Cirrhosis, Experimental 23 | 769
astrocytoma 23 | 1,146
Asthma 22 | 385
Melanoma 22 | 711
gastric carcinoma 22 | 807
group 4 medulloblastoma 22 | 1,855
adrenocortical carcinoma 20 | 1,428
astrocytic glioma 20 | 2,597
esophageal adenocarcinoma 20 | 737
primary Sjogren syndrome 20 | 735
spina bifida 20 | 1,074
Hypersensitivity reaction type II disease 19 | 253
Obesity 19 | 678
nasopharyngeal carcinoma 19 | 1,058
dermatomyositis 18 | 966
primary pancreatic ductal adenocarcinoma 18 | 1,109
Hypertensive disease 17 | 292
Kidney disease 17 | 430
Multiple myeloma 17 | 1,332
Pick disease 17 | 1,894
active ulcerative colitis 17 | 764
Heart disease 16 | 306
Lung disease 16 | 142
Pneumonia 16 | 174
active Crohn's disease 16 | 922
non-small cell lung carcinoma 16 | 317
Arthritis 15 | 290
Atopic dermatitis 15 | 952
Bipolar Disorder 15 | 666
Breast Neoplasms 15 | 445
Diarrhea 15 | 253
Human immunodeficiency virus infectious disease 15 | 138
Mammary Neoplasms 15 | 425
Anemia 14 | 365
Immunologic Deficiency Syndromes 14 | 113
Inflammation 14 | 120
fibroadenoma 14 | 559
Endometriosis 13 | 540
Intellectual disability 13 | 1,016
Major Depressive Disorder 13 | 301
Vascular disease 13 | 319
head and neck cancer and chronic obstructive pulmonary disease 13 | 239
medulloblastoma 13 | 720
Arthritis, Rheumatoid 12 | 174
Cerebrovascular disease 12 | 238
Down syndrome 12 | 499
Duchenne muscular dystrophy 12 | 601
Inflammatory bowel disease 12 | 151
Malaria 12 | 160
Splenomegaly 12 | 190
head and neck cancer 12 | 271
hepatocellular carcinoma 12 | 547
pediatric high grade glioma 12 | 1,064
sarcoidosis 12 | 370
Immune system cancer 11 | 140

Tissue

Endocrine System 233 | 18,159
Female tissues 229 | 17,400
Digestive Tract 228 | 17,369
Skin and soft tissues 228 | 17,230
Liver and Pancreas 227 | 16,750
Male tissues 226 | 17,142
Urinary Tract 224 | 16,678
Blood and immune system 222 | 16,909
Respiratory system 221 | 16,393
Nervous System 211 | 16,725
Cardiovascular System 204 | 15,192

Target Family

Non-IDG 139 | 12,091
GPCR 65 | 408
Kinase 15 | 634
Enzyme 14 | 4,145
Ion Channel 3 | 344
Epigenetic 2 | 242
Transcription Factor 1 | 1,400

GO Process

cell surface receptor signalin... 239 | 239
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tetraspanin-16 TSPAN16 Tdark Non-IDG -1.99505 87.0 42
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
CD160 antigen CD160 Tbio Non-IDG -1.70035 55.1 428
Immunoglobulin superfamily member 6 IGSF6 Tbio Non-IDG -1.87882 72.2 146
E3 ubiquitin-protein ligase DTX1 DTX1 Tbio Enzyme -2.07595 115.2 134
Calcineurin-binding protein cabin-1 CABIN1 Tbio Non-IDG -3.37173 2194.3 57
Thrombopoietin receptor MPL Tclin Non-IDG -2.74303 582.0 186
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Vasoactive intestinal polypeptide receptor 2 VIPR2 Tchem GPCR -2.20668 142.1 255