Development Level

Tbio 49 | 10,625
Tchem 16 | 1,890
Tdark 8 | 7,003
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal limb bud morphology 2 | 15
abnormal testis morphology 2 | 30
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
embryonic lethality prior to t... 2 | 187
increased gamma-delta T cell n... 2 | 16
small testis 2 | 37
abnormal allantois morphology 1 | 3
abnormal chorioallantoic fusio... 1 | 2
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eyelid morphology 1 | 6
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal head size 1 | 1
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
abnormal thoracic vertebrae mo... 1 | 16
anophthalmia 1 | 20
cataract 1 | 26
cleft palate 1 | 6
craniofacial phenotype 1 | 9
decreased NK cell number 1 | 16
decreased alpha-beta T cell nu... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
enlarged epididymis 1 | 27
enlarged heart 1 | 111
facial cleft 1 | 3
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
increased spleen weight 1 | 3
increased startle reflex 1 | 38
mydriasis 1 | 9
pale yolk sac 1 | 12
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small adrenal glands 1 | 15
small seminal vesicle 1 | 6
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 43 | 8,484
lung cancer 33 | 4,466
osteosarcoma 33 | 7,933
psoriasis 29 | 6,685
glioblastoma 28 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
medulloblastoma, large-cell 22 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Cancer 19 | 2,346
Multiple myeloma 18 | 1,327
non-small cell lung cancer 18 | 2,798
atypical teratoid / rhabdoid tumor 17 | 4,369
diabetes mellitus 17 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
invasive ductal carcinoma 17 | 2,950
tuberculosis 17 | 1,557
Breast cancer 16 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
lung adenocarcinoma 16 | 2,713
lung carcinoma 16 | 2,844
malignant mesothelioma 16 | 3,162
ulcerative colitis 16 | 2,087
pancreatic cancer 15 | 2,300
interstitial cystitis 14 | 2,299
pediatric high grade glioma 14 | 2,712
pilocytic astrocytoma 14 | 3,086
Prostatic Neoplasms 12 | 471
acute quadriplegic myopathy 12 | 1,157
oligodendroglioma 12 | 2,849
primitive neuroectodermal tumor 11 | 3,031
active Crohn's disease 10 | 918
posterior fossa group A ependymoma 10 | 1,511
Diabetes Mellitus, Experimental 9 | 106
Kidney disease 9 | 396
Waldenstrons macroglobulinemia 9 | 765
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
ependymoma 9 | 2,514
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
Hypertensive disease 8 | 193
IGA Glomerulonephritis 8 | 454
Neurodegenerative disease 8 | 383
acute myeloid leukemia 8 | 780
astrocytic glioma 8 | 2,241
group 3 medulloblastoma 8 | 2,254
juvenile dermatomyositis 8 | 1,189
Rheumatoid Arthritis 7 | 1,160
Toxic encephalopathy 7 | 131
Vascular disease 7 | 281
adult high grade glioma 7 | 2,148
cutaneous lupus erythematosus 7 | 1,056
cystic fibrosis 7 | 1,665
group 4 medulloblastoma 7 | 1,875
primary pancreatic ductal adenocarcinoma 7 | 1,271
Amyotrophic Lateral Sclerosis 6 | 431
Atherosclerosis 6 | 275
Cerebrovascular disease 6 | 231
Contact Dermatitis 6 | 80
Hypertension 6 | 287
Liver carcinoma 6 | 217
Myocardial Infarction 6 | 126
Myocardial Ischemia 6 | 169
Osteoporosis 6 | 257
adrenocortical carcinoma 6 | 1,427
esophageal adenocarcinoma 6 | 737
non primary Sjogren syndrome sicca 6 | 840
Acute kidney injury 5 | 65
Alzheimer's disease 5 | 644
Brain Ischemia 5 | 87
Chronic granulomatous disease 5 | 13
Diabetes Mellitus, Insulin-Dependent 5 | 76
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Down syndrome 5 | 548
Drug-Induced Liver Injury 5 | 118
Duchenne muscular dystrophy 5 | 602
Hyperglycemia 5 | 120
Mammary Neoplasms 5 | 410
Reperfusion Injury 5 | 84
dermatomyositis 5 | 933
medulloblastoma 5 | 1,524
periodontitis 5 | 269
sonic hedgehog group medulloblastoma 5 | 1,482
Carcinoma 4 | 2,147
Chronic Lymphocytic Leukemia 4 | 242
Crohn's disease 4 | 304
Heart disease 4 | 279
Inflammation 4 | 109
Male infertility 4 | 170
Multiple Sclerosis 4 | 498
Peripheral Neuropathy 4 | 303
Pick disease 4 | 1,893
Seizures 4 | 95
Stomach Neoplasms 4 | 282
gastric carcinoma 4 | 832
inflammatory breast cancer 4 | 404
mucosa-associated lymphoid tissue lymphoma 4 | 480
non-small cell lung carcinoma 4 | 413
pancreatic carcinoma 4 | 567
spina bifida 4 | 1,064

Tissue

Digestive Tract 76 | 18,473
Endocrine System 76 | 18,512
Nervous System 76 | 18,561
Female tissues 75 | 18,647
Liver and Pancreas 75 | 18,136
Urinary Tract 75 | 18,444
Blood and immune system 74 | 17,995
Cardiovascular System 74 | 17,958
Male tissues 73 | 17,969
Respiratory system 73 | 17,484
Skin and soft tissues 73 | 18,115

Target Family

Non-IDG 48 | 11,971
Enzyme 24 | 4,146
Transcription Factor 2 | 1,400
Ion Channel 1 | 341
Transporter 1 | 473

GO Process

cell redox homeostasis 76 | 76
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NHL repeat-containing protein 2 NHLRC2 Tdark Non-IDG 0.78 1.17 50
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Cathelicidin antimicrobial peptide CAMP Tbio Non-IDG -3.26418 1961.9 0
Protein disulfide-isomerase A4 PDIA4 Tbio Enzyme -1.63645 41.6 248
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.97339 830.6 224
Glutamate--cysteine ligase catalytic subunit GCLC Tchem Enzyme -2.40511 266.2 257
Lactotransferrin LTF Tbio Non-IDG -2.51208 332.5 794
Glutaredoxin-3 GLRX3 Tbio Non-IDG -1.86821 85.0 198