Development Level

Tbio 49 | 11,651
Tchem 11 | 1,388
Tdark 9 | 6,593
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal limb bud morphology 2 | 17
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
decreased circulating amylase ... 2 | 28
decreased circulating insulin ... 2 | 76
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal heart looping 1 | 5
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal snout morphology 1 | 23
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart 1 | 210
facial cleft 1 | 3
hyperactivity 1 | 148
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
short tibia 1 | 97
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

ovarian cancer 43 | 8,520
Carcinoma 41 | 11,493
lung cancer 32 | 4,740
osteosarcoma 32 | 7,950
glioblastoma 29 | 5,792
psoriasis 27 | 6,694
atypical teratoid / rhabdoid tumor 24 | 5,112
medulloblastoma, large-cell 22 | 6,241
Cancer 21 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Multiple myeloma 19 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ependymoma 18 | 4,679
diabetes mellitus 17 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 16 | 2,951
lung carcinoma 16 | 2,843
non-small cell lung cancer 16 | 2,890
Breast cancer 15 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
malignant mesothelioma 15 | 3,232
tuberculosis 15 | 2,010
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 14 | 4,104
pancreatic cancer 14 | 2,398
acute quadriplegic myopathy 13 | 1,158
interstitial cystitis 13 | 2,312
lung adenocarcinoma 13 | 2,716
ulcerative colitis 13 | 1,819
Prostatic Neoplasms 12 | 495
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 10 | 3,035
Autosomal recessive predisposition 9 | 1,442
Hypertension 9 | 396
Kidney disease 9 | 430
Vascular disease 9 | 319
active Crohn's disease 9 | 922
Diabetes Mellitus, Experimental 8 | 108
Hypertensive disease 8 | 292
Toxic encephalopathy 8 | 141
acute myeloid leukemia 8 | 783
astrocytic glioma 8 | 2,597
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
pituitary cancer 8 | 1,972
Alzheimer's disease 7 | 658
Carcinoma, Hepatocellular 7 | 228
Fever 7 | 138
Neurodegenerative disease 7 | 414
Rheumatoid arthritis 7 | 1,191
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
cutaneous lupus erythematosus 7 | 1,057
non primary Sjogren syndrome sicca 7 | 891
subependymal giant cell astrocytoma 7 | 2,287
Atherosclerosis 6 | 291
Cerebrovascular disease 6 | 238
Chronic Obstructive Airway Disease 6 | 37
Contact Dermatitis 6 | 81
Dermatitis, Contact 6 | 71
Liver Cirrhosis, Experimental 6 | 769
Liver carcinoma 6 | 240
Lung Neoplasms 6 | 232
Myocardial Infarction 6 | 151
Myocardial Ischemia 6 | 169
Schizophrenia 6 | 1,160
Seizures 6 | 596
cystic fibrosis 6 | 1,696
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
Acute kidney injury 5 | 70
Amyotrophic lateral sclerosis 5 | 451
Arthritis, Rheumatoid 5 | 174
Brain Ischemia 5 | 110
Breast Neoplasms 5 | 445
Chronic granulomatous disease 5 | 13
Depressive disorder 5 | 409
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Heart disease 5 | 306
Heart failure 5 | 162
Hyperglycemia 5 | 137
Mammary Neoplasms 5 | 425
Osteoporosis 5 | 363
Otitis Media 5 | 52
Paranasal Sinus Diseases 5 | 34
Pyloric Stenosis 5 | 47
Recurrent respiratory infections 5 | 141
Reperfusion Injury 5 | 86
Sinusitis 5 | 65
adrenocortical carcinoma 5 | 1,428
primary pancreatic ductal adenocarcinoma 5 | 1,109
Kidney cancer 4 | 2,613
Mental Depression 4 | 333
dermatomyositis 4 | 966
periodontitis 4 | 293
spina bifida 4 | 1,074

Tissue

Endocrine System 72 | 18,159
Male tissues 72 | 17,142
Blood and immune system 71 | 16,909
Urinary Tract 71 | 16,678
Digestive Tract 70 | 17,369
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750
Nervous System 70 | 16,725
Respiratory system 70 | 16,393
Skin and soft tissues 70 | 17,230
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 45 | 12,091
Enzyme 23 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

cell redox homeostasis 72 | 72
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein disulfide-isomerase TMX3 TMX3 Tbio Enzyme -0.72922 5.29 80
Peroxiredoxin-4 PRDX4 Tbio Non-IDG -2.02710 109.0 300
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Endoplasmic reticulum resident protein 44 ERP44 Tbio Non-IDG -1.46425 28.0 204
Thioredoxin, mitochondrial TXN2 Tbio Non-IDG -2.05954 125.2 260
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
ERO1-like protein beta ERO1B Tbio Non-IDG -0.92111 8.62 114
Thioredoxin-related transmembrane protein 2 TMX2 Tdark Non-IDG -0.92875 7.36 50
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.47746 2989.0 646
Thioredoxin domain-containing protein 12 TXNDC12 Tbio Non-IDG -1.48767 32.4 103