Development Level

Tbio 25 | 10,625
Tdark 3 | 7,003
Tchem 2 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal testis morphology 1 | 30
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased follicular B cell nu... 1 | 4
enlarged uterus 1 | 3
hydrometra 1 | 13
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

ovarian cancer 14 | 8,492
medulloblastoma, large-cell 11 | 6,234
osteosarcoma 11 | 7,933
glioblastoma 10 | 5,572
psoriasis 9 | 6,685
posterior fossa group B ependymoma 8 | 1,530
lung cancer 7 | 4,473
atypical teratoid / rhabdoid tumor 6 | 4,369
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,163
pediatric high grade glioma 6 | 2,712
Cancer 5 | 2,346
Carcinoma 5 | 2,147
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung adenocarcinoma 5 | 2,714
nasopharyngeal carcinoma 5 | 1,056
non-small cell lung cancer 5 | 2,798
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
Breast cancer 4 | 3,099
Ciliopathy 4 | 57
atypical teratoid/rhabdoid tumor 4 | 1,095
ependymoma 4 | 2,514
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
subependymal giant cell astrocytoma 4 | 2,287
adult high grade glioma 3 | 2,148
group 3 medulloblastoma 3 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
invasive ductal carcinoma 3 | 2,950
Asphyxiating thoracic dystrophy 2 | 34
Asthma 2 | 349
Epilepsy 2 | 346
Intellectual disability 2 | 573
Joubert syndrome 2 | 62
Kidney disease 2 | 397
Nephronophthisis 2 | 74
Osteoporosis 2 | 259
Parkinson's disease 2 | 364
Polydactyly 2 | 93
Primary ciliary dyskinesia 2 | 75
Schizophrenia 2 | 503
Situs Inversus 2 | 52
Specific language impairment 2 | 31
Squamous cell carcinoma 2 | 96
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,663
ovarian neoplasm 2 | 97
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 789
ulcerative colitis 2 | 2,087
urothelial carcinoma 2 | 318
Aarskog-Scott syndrome 1 | 11
Acute Promyelocytic Leukemia 1 | 32
Adenomatous Polyposis Coli 1 | 10
Agammaglobulinemia 1 | 24
Apraxia 1 | 25
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 7
Brain Diseases 1 | 22
Breast adenocarcinoma 1 | 8
Cardiomegaly 1 | 66
Centronuclear myopathy 1 | 21
Colon Carcinoma 1 | 25
Cowden disease 1 | 20
Cystic kidney disease 1 | 26
Diabetic Retinopathy 1 | 53
Dyslexia 1 | 36
Eosinophilic esophagitis 1 | 31
Fleck corneal dystrophy 1 | 9
Galactosemia 1 | 20
Hyperglycemia 1 | 120
Hyperinsulinism 1 | 63
Joubert syndrome 4 1 | 3
Kartagener Syndrome 1 | 32
Kindler syndrome 1 | 10
Meningioma 1 | 27
Mouth Neoplasms 1 | 44
Neurofibromatosis 1 | 37
Nonepidermolytic palmoplantar keratoderma 1 | 12
Oculocerebrorenal syndrome 1 | 24
PSEUDOHYPOALDOSTERONISM, TYPE IIE 1 | 1
Pain 1 | 70
Papillary thyroid carcinoma 1 | 37
Primary progressive multiple sclerosis 1 | 3
Pseudohypoaldosteronism 2E 1 | 1
Pseudohypoaldosteronism type 2E 1 | 1
Pseudohypoaldosteronism, Type II 1 | 2
Pseudohypoaldosteronism, type 2 1 | 4
Psychoses, Substance-Induced 1 | 17
Respiratory failure 1 | 30
Salpingitis 1 | 6
Short-rib thoracic dysplasia 3 with or without polydactyly 1 | 9
Skin Neoplasms 1 | 49
Spinocerebellar ataxia type 17 1 | 7
Tracheal stenosis 1 | 18
alcohol-related neurodevelopmental disorder 1 | 11
end stage renal failure 1 | 7

Tissue

Blood and immune system 30 | 17,995
Cardiovascular System 30 | 17,958
Digestive Tract 30 | 18,473
Endocrine System 30 | 18,512
Female tissues 30 | 18,647
Liver and Pancreas 30 | 18,136
Male tissues 30 | 17,969
Nervous System 30 | 18,561
Respiratory system 30 | 17,484
Skin and soft tissues 30 | 18,115
Urinary Tract 30 | 18,444

Target Family

Non-IDG 26 | 11,969
Kinase 2 | 634
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

GO Process

cell projection organization 30 | 30
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.32386 18275.3 3137
Hamartin TSC1 Tbio Non-IDG -2.23602 165.3 1376
Cullin-3 CUL3 Tbio Non-IDG -3.19710 1383.0 295
Pleckstrin PLEK Tbio Non-IDG -2.99140 713.7 264
MAP/microtubule affinity-regulating kinase 4 MARK4 Tchem Kinase -1.54611 37.9 256
Doublecortin domain-containing protein 2 DCDC2 Tbio Non-IDG -1.66827 47.2 189
Twinfilin-2 TWF2 Tbio Non-IDG -1.17706 16.6 143
Huntingtin-associated protein 1 HAP1 Tbio Non-IDG -1.89880 81.0 142
Transcription factor E2F5 E2F5 Tbio Transcription Factor -1.67075 39.5 123
Integrin alpha-8 ITGA8 Tbio Non-IDG -1.30330 19.3 110