Development Level

Tbio 23 | 11,651
Tchem 5 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal gait 2 | 69
hyperactivity 2 | 148
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal testis morphology 1 | 43
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
male infertility 1 | 123
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
vertebral fusion 1 | 23

Disease

Carcinoma 22 | 11,493
ovarian cancer 16 | 8,520
psoriasis 16 | 6,694
glioblastoma 15 | 5,792
osteosarcoma 14 | 7,950
atypical teratoid / rhabdoid tumor 13 | 5,112
Breast cancer 12 | 3,578
malignant mesothelioma 12 | 3,232
ependymoma 11 | 4,679
medulloblastoma, large-cell 11 | 6,241
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
Astrocytoma, Pilocytic 9 | 3,081
diabetes mellitus 9 | 1,728
lung cancer 9 | 4,740
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Polycystic ovary syndrome 6 | 360
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
oligodendroglioma 6 | 2,850
pituitary cancer 6 | 1,972
Endometriosis 5 | 540
Hypertensive disease 5 | 292
Multiple myeloma 5 | 1,332
gastric carcinoma 5 | 807
interstitial cystitis 5 | 2,312
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Bipolar Disorder 4 | 666
Cleft Palate 4 | 271
Hernia, Inguinal 4 | 89
Kidney cancer 4 | 2,613
Liver Cirrhosis, Experimental 4 | 769
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
ulcerative colitis 4 | 1,819
Acquired flat foot 3 | 72
Acquired scoliosis 3 | 281
Aortic Valve Insufficiency 3 | 40
Asthma 3 | 385
Atopic dermatitis 3 | 952
Azoospermia 3 | 110
Byzanthine arch palate 3 | 194
Cell Transformation, Neoplastic 3 | 97
Coronary artery disease 3 | 268
Craniofacial Abnormalities 3 | 151
Curvature of spine 3 | 282
Decreased tendon reflex 3 | 122
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Duchenne muscular dystrophy 3 | 601
Fever 3 | 138
Flatfoot 3 | 73
Hypersensitivity reaction type II disease 3 | 253
Hypertension 3 | 396
Mesothelioma, Malignant 3 | 105
Neoplastic Cell Transformation 3 | 89
Neurodegenerative disease 3 | 414
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Osteoporosis 3 | 363
Skeletal muscle atrophy 3 | 139
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
muscle degeneration 3 | 139
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sarcoidosis 3 | 370
sonic hedgehog group medulloblastoma 3 | 467
Carcinoma, Hepatocellular 2 | 228
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Infertility 2 | 188
Liver Cirrhosis 2 | 181
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Myopathy 2 | 185
Neuropathy 2 | 261
Psychotic Disorders 2 | 151
Skin cancer 2 | 469
Unipolar Depression 2 | 250
medulloblastoma 2 | 720

Tissue

Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Blood and immune system 30 | 16,909

Target Family

Non-IDG 20 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

cell growth 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 3 EMP3 Tbio Non-IDG -1.68085 47.8 164
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.77688 547.0 828
Erbin ERBIN Tbio Non-IDG -1.72357 59.1 117
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 Tbio Enzyme -2.99264 1021.1 225
4F2 cell-surface antigen heavy chain SLC3A2 Tbio Transporter -2.82471 653.6 604
Protein transport protein Sec61 subunit alpha isoform 1 SEC61A1 Tbio Non-IDG -2.46663 293.5 120
Apoptosis regulator Bcl-2 BCL2 Tclin Non-IDG -2.20455 130.6 2273
Serine/threonine-protein kinase PAK 4 PAK4 Tchem Kinase -2.23261 194.7 436