Development Level

Tbio 354 | 11,651
Tdark 99 | 6,593
Tchem 45 | 1,388
Tclin 13 | 612

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 22 | 499
abnormal bone structure 13 | 187
abnormal behavior 11 | 298
decreased body weight 8 | 161
decreased vertical activity 8 | 208
enlarged heart 7 | 210
male infertility 7 | 123
decreased lean body mass 6 | 135
increased bone mineral content 6 | 108
abnormal embryo size 5 | 220
abnormal seminal vesicle morph... 5 | 114
decreased body length 5 | 101
decreased total body fat amoun... 5 | 207
embryonic lethality prior to t... 5 | 278
hyperactivity 5 | 148
increased circulating alkaline... 5 | 122
increased monocyte cell number 5 | 63
prenatal lethality prior to he... 5 | 87
decreased bone mineral density 4 | 126
decreased circulating glucose ... 4 | 126
decreased circulating triglyce... 4 | 79
decreased erythrocyte cell num... 4 | 62
decreased grip strength 4 | 116
decreased hematocrit 4 | 46
decreased lymphocyte cell numb... 4 | 83
female infertility 4 | 60
increased blood urea nitrogen ... 4 | 48
increased grip strength 4 | 41
increased lean body mass 4 | 172
small superior vagus ganglion 4 | 74
abnormal coat-hair pigmentatio... 3 | 64
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal heart morphology 3 | 162
abnormal kidney morphology 3 | 65
abnormal sleep behavior 3 | 70
abnormal snout morphology 3 | 23
abnormal testis morphology 3 | 43
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased hemoglobin content 3 | 68
edema 3 | 59
embryonic lethality prior to o... 3 | 239
increased leukocyte cell numbe... 3 | 47
increased total body fat amoun... 3 | 134
abnormal eye morphology 2 | 68
abnormal facial morphology 2 | 17
abnormal head size 2 | 6
abnormal locomotor activation 2 | 16
abnormal maxilla morphology 2 | 17
abnormal spleen morphology 2 | 55
anophthalmia 2 | 33
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased circulating fructosa... 2 | 30
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased heart rate 2 | 18
decreased prepulse inhibition 2 | 82
hydrometra 2 | 53
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased circulating iron lev... 2 | 30
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased vertical activity 2 | 24
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
small adrenal glands 2 | 16
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal hair growth 1 | 10
abnormal lens morphology 1 | 81
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
decreased T cell number 1 | 15
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
enlarged lymph nodes 1 | 37
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
long tibia 1 | 25
small kidney 1 | 16
thin ventricular wall 1 | 24
trunk curl 1 | 16

Disease

Carcinoma 305 | 11,493
ovarian cancer 212 | 8,520
osteosarcoma 191 | 7,950
psoriasis 177 | 6,694
medulloblastoma, large-cell 160 | 6,241
glioblastoma 143 | 5,792
lung cancer 139 | 4,740
atypical teratoid / rhabdoid tumor 137 | 5,112
ependymoma 127 | 4,679
group 3 medulloblastoma 108 | 4,104
Breast cancer 105 | 3,578
malignant mesothelioma 102 | 3,232
Cancer 99 | 2,499
invasive ductal carcinoma 90 | 2,951
non-small cell lung cancer 90 | 2,890
adult high grade glioma 89 | 3,801
Astrocytoma, Pilocytic 86 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 83 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 81 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 80 | 2,955
lung adenocarcinoma 80 | 2,716
lung carcinoma 79 | 2,843
Kidney cancer 76 | 2,613
interstitial cystitis 76 | 2,312
oligodendroglioma 75 | 2,850
primitive neuroectodermal tumor 74 | 3,035
pancreatic cancer 70 | 2,398
astrocytic glioma 67 | 2,597
pituitary cancer 64 | 1,972
cystic fibrosis 57 | 1,696
subependymal giant cell astrocytoma 56 | 2,287
breast carcinoma 55 | 1,638
ductal carcinoma in situ 55 | 1,745
tuberculosis 55 | 2,010
ulcerative colitis 52 | 1,819
colon cancer 50 | 1,478
group 4 medulloblastoma 46 | 1,855
adrenocortical carcinoma 44 | 1,428
Pick disease 40 | 1,894
diabetes mellitus 39 | 1,728
cutaneous lupus erythematosus 38 | 1,057
spina bifida 38 | 1,074
juvenile dermatomyositis 37 | 1,187
primary pancreatic ductal adenocarcinoma 36 | 1,109
nasopharyngeal carcinoma 32 | 1,058
Autosomal recessive predisposition 31 | 1,442
Multiple myeloma 31 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Intellectual disability 29 | 1,016
Male infertility 29 | 206
Schizophrenia 29 | 1,160
astrocytoma 29 | 1,146
gastric carcinoma 28 | 807
Atopic dermatitis 27 | 952
pediatric high grade glioma 27 | 1,064
Obesity 26 | 678
Rheumatoid arthritis 26 | 1,191
non primary Sjogren syndrome sicca 26 | 891
Melanoma 25 | 711
fibroadenoma 25 | 559
Breast Neoplasms 24 | 445
Mammary Neoplasms 24 | 425
active Crohn's disease 23 | 922
medulloblastoma 23 | 720
Bipolar Disorder 22 | 666
Dull intelligence 22 | 645
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
dermatomyositis 22 | 966
primary Sjogren syndrome 22 | 735
Cryptorchidism 21 | 296
Infertility 21 | 188
Down syndrome 20 | 499
Skin cancer 20 | 469
active ulcerative colitis 20 | 764
acute myeloid leukemia 20 | 783
acute quadriplegic myopathy 20 | 1,158
esophageal adenocarcinoma 20 | 737
Endometriosis 19 | 540
Prostatic Neoplasms 19 | 495
aldosterone-producing adenoma 19 | 665
posterior fossa group B ependymoma 19 | 416
Alzheimer's disease 18 | 658
Cognitive delay 18 | 608
Global developmental delay 18 | 608
Liver Cirrhosis, Experimental 18 | 769
Mental and motor retardation 18 | 608
sonic hedgehog group medulloblastoma 18 | 467
Cleft Palate 17 | 271
Muscle hypotonia 17 | 571
Craniofacial Abnormalities 16 | 151
Azoospermia 15 | 110
Blepharoptosis 15 | 231
Osteoporosis 15 | 363
Strabismus 15 | 270
Waldenstrons macroglobulinemia 15 | 765
hepatocellular carcinoma 15 | 547
urothelial carcinoma 15 | 318

Tissue

Endocrine System 491 | 18,159
Digestive Tract 449 | 17,369
Skin and soft tissues 441 | 17,230
Female tissues 437 | 17,400
Male tissues 436 | 17,142
Blood and immune system 426 | 16,909
Nervous System 422 | 16,725
Liver and Pancreas 417 | 16,750
Urinary Tract 411 | 16,678
Respiratory system 403 | 16,393
Cardiovascular System 355 | 15,192

Target Family

Non-IDG 278 | 12,091
Transcription Factor 129 | 1,400
Enzyme 41 | 4,145
Kinase 37 | 634
Epigenetic 11 | 242
Transporter 6 | 473
Nuclear Receptor 4 | 48
Ion Channel 3 | 344
GPCR 1 | 408
TF/Epigenetic 1 | 38

GO Process

cell differentiation 511 | 511
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
ETS-related transcription factor Elf-2 ELF2 Tbio Transcription Factor -2.04794 106.4 92
Serine/threonine-protein kinase MAK MAK Tchem Kinase -1.20155 15.2 266
BTB/POZ domain-containing protein 18 BTBD18 Tdark Non-IDG -0.42597 2.79 11
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Unconventional myosin-VIIb MYO7B Tbio Non-IDG -0.65885 5.07 14
EP300-interacting inhibitor of differentiation 2 EID2 Tbio Non-IDG -1.36642 21.1 65
Deleted in azoospermia protein 1 DAZ1 Tbio Non-IDG -2.24914 176.6 159
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83