Development Level

Tbio 36 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
decreased body weight 2 | 161
decreased vertical activity 2 | 208
edema 2 | 59
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
decreased B cell number 1 | 5
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating potassiu... 1 | 29
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 23 | 11,493
psoriasis 15 | 6,694
lung cancer 12 | 4,740
ovarian cancer 12 | 8,520
osteosarcoma 11 | 7,950
Breast cancer 10 | 3,578
Cancer 10 | 2,499
glioblastoma 10 | 5,792
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
ductal carcinoma in situ 8 | 1,745
Cleft Palate 7 | 271
Coronary artery disease 7 | 268
adult high grade glioma 7 | 3,801
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
Microphthalmia 6 | 76
atypical teratoid / rhabdoid tumor 6 | 5,112
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
Acquired scoliosis 5 | 281
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
Cleft Lip 5 | 141
Coloboma 5 | 51
Curvature of spine 5 | 282
Hypertensive disease 5 | 292
Short stature 5 | 531
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
Aortic Valve Insufficiency 4 | 40
Bilateral fifth finger clinodactyly 4 | 110
Carcinoma, Hepatocellular 4 | 228
Cataract 4 | 297
Curvature of little finger 4 | 110
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Polycystic ovary syndrome 4 | 360
Premature ovarian failure 4 | 65
Visceral heterotaxy 4 | 14
gastric carcinoma 4 | 807
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Abnormally small eyeball 3 | 97
Acquired flat foot 3 | 72
Ankylosis 3 | 28
Arthritis, Rheumatoid 3 | 174
Brachydactyly 3 | 156
Cardiomegaly 3 | 116
Chest Pain 3 | 38
Congenital heart disease 3 | 93
Congenital ocular coloboma (disorder) 3 | 40
Cutis marmorata 3 | 32
Cystic medial necrosis of aorta 3 | 13
Decreased size of eyeball 3 | 97
Dyspnea on exertion 3 | 24
Dyspnea, Paroxysmal 3 | 13
Exophthalmos 3 | 112
Flatfoot 3 | 73
Heart disease 3 | 306
Hypotrophic malar bone 3 | 129
Impaired left ventricular function 3 | 16
Increase in blood pressure 3 | 119
Infertility 3 | 188
Intrauterine retardation 3 | 176
Kidney cancer 3 | 2,613
Left-Sided Heart Failure 3 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 3 | 13
Malar flattening 3 | 129
Microphthalmos 3 | 100
Myopia 3 | 176
Osteoarthritis 3 | 184
Osteoporosis 3 | 363
Otosclerosis 3 | 15
Pre-Eclampsia 3 | 68
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Rheumatoid arthritis 3 | 1,191
Right atrial isomerism 3 | 29
Situs ambiguus 3 | 25
astrocytic glioma 3 | 2,597
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109
sarcoidosis 3 | 370
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 39 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Digestive Tract 32 | 17,369
Respiratory system 31 | 16,393
Blood and immune system 30 | 16,909
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 30 | 12,091
Transcription Factor 7 | 1,400
Enzyme 2 | 4,145

GO Process

cell development 39 | 39
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Forkhead box protein E3 FOXE3 Tbio Transcription Factor -1.53701 31.5 150
Class E basic helix-loop-helix protein 23 BHLHE23 Tdark Transcription Factor -0.95464 7.69 15
Embryonic growth/differentiation factor 1 GDF1 Tbio Non-IDG -2.00590 102.6 64
Heat shock factor protein 4 HSF4 Tbio Transcription Factor -2.82845 672.2 263
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110