Development Level

Tbio 104 | 11,445
Tchem 26 | 1,598
Tclin 6 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal heart morphology 6 | 162
embryonic lethality prior to o... 6 | 239
enlarged heart 6 | 210
decreased vertical activity 5 | 208
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal eye morphology 3 | 68
abnormal lens morphology 3 | 81
abnormal lung morphology 3 | 26
cataract 3 | 92
decreased circulating insulin ... 3 | 76
decreased mean corpuscular vol... 3 | 79
enlarged spleen 3 | 41
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
decreased startle reflex 2 | 75
edema 2 | 59
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged thymus 1 | 5
hydroencephaly 1 | 14
hypoactivity 1 | 132
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased coping response 1 | 4
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased glycosylated hemoglo... 1 | 1
increased lean body mass 1 | 172
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased vertical activity 1 | 24
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 87 | 11,493
ovarian cancer 86 | 8,520
osteosarcoma 68 | 7,950
Cancer 67 | 2,499
glioblastoma 61 | 5,792
medulloblastoma, large-cell 61 | 6,241
psoriasis 59 | 6,694
atypical teratoid / rhabdoid tumor 52 | 5,112
lung cancer 52 | 4,740
ependymoma 49 | 4,679
Breast cancer 47 | 3,578
group 3 medulloblastoma 46 | 4,104
malignant mesothelioma 43 | 3,232
adult high grade glioma 36 | 3,801
Astrocytoma, Pilocytic 31 | 3,081
Kidney cancer 31 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
oligodendroglioma 31 | 2,850
astrocytic glioma 30 | 2,597
invasive ductal carcinoma 30 | 2,951
pancreatic cancer 30 | 2,398
pituitary cancer 30 | 1,972
primitive neuroectodermal tumor 30 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
lung carcinoma 26 | 2,843
diabetes mellitus 25 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
subependymal giant cell astrocytoma 24 | 2,287
adrenocortical carcinoma 23 | 1,428
ductal carcinoma in situ 22 | 1,745
tuberculosis 22 | 2,010
breast carcinoma 20 | 1,638
non-small cell lung cancer 20 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Breast Neoplasms 19 | 445
Stomach Neoplasms 18 | 300
astrocytoma 18 | 1,146
lung adenocarcinoma 18 | 2,716
Lung Neoplasms 17 | 232
Mammary Neoplasms 17 | 425
Multiple myeloma 17 | 1,332
Pick disease 17 | 1,894
Rheumatoid arthritis 17 | 1,191
acute quadriplegic myopathy 17 | 1,158
colon cancer 17 | 1,478
group 4 medulloblastoma 17 | 1,855
ulcerative colitis 17 | 1,819
Melanoma 16 | 711
Schizophrenia 16 | 1,160
juvenile dermatomyositis 16 | 1,187
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
interstitial cystitis 15 | 2,312
Epilepsy 14 | 792
Liver carcinoma 14 | 240
cystic fibrosis 14 | 1,696
Carcinoma, Squamous Cell 13 | 110
Prostatic Neoplasms 13 | 495
medulloblastoma 13 | 720
primary pancreatic ductal adenocarcinoma 13 | 1,109
Adenocarcinoma 12 | 122
Carcinoma, Hepatocellular 12 | 228
Kidney disease 12 | 430
Vascular disease 12 | 319
acute myeloid leukemia 12 | 783
nasopharyngeal carcinoma 12 | 1,058
Autosomal recessive predisposition 11 | 1,442
Liver cancer 11 | 604
Liver neoplasms 11 | 130
Skin cancer 11 | 469
Squamous cell carcinoma 11 | 129
gastric carcinoma 11 | 807
non primary Sjogren syndrome sicca 11 | 891
pediatric high grade glioma 11 | 1,064
Alzheimer's disease 10 | 658
Immune system cancer 10 | 140
Intellectual disability 10 | 1,016
Pancreatic Neoplasm 10 | 85
Pancreatic Neoplasms 10 | 85
Seizures 10 | 596
Short stature 10 | 531
hepatocellular carcinoma 10 | 547
Adenoma 9 | 167
Bladder Neoplasm 9 | 112
Diarrhea 9 | 253
Lymphoid leukemia 9 | 160
Mesothelioma, Malignant 9 | 105
Multiple Sclerosis 9 | 540
Urinary Bladder Neoplasms 9 | 114
non-small cell lung carcinoma 9 | 317
spina bifida 9 | 1,074
Bipolar Disorder 8 | 666
Dull intelligence 8 | 645
Hypoplastic mandible condyle 8 | 275
Low intelligence 8 | 645
Mandibular hypoplasia 8 | 275
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Micrognathism 8 | 275
Poor school performance 8 | 645
dermatomyositis 8 | 966

Tissue

Endocrine System 140 | 18,159
Female tissues 139 | 17,400
Male tissues 139 | 17,142
Skin and soft tissues 139 | 17,230
Blood and immune system 138 | 16,909
Digestive Tract 137 | 17,369
Nervous System 137 | 16,725
Respiratory system 137 | 16,393
Liver and Pancreas 136 | 16,750
Urinary Tract 136 | 16,678
Cardiovascular System 132 | 15,192

Target Family

Non-IDG 83 | 12,091
Kinase 22 | 634
Enzyme 19 | 4,145
Transcription Factor 13 | 1,400
Epigenetic 3 | 242
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

cell cycle arrest 142 | 142
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein BTG4 BTG4 Tbio Non-IDG -1.04941 12.0 112
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Nuclear protein 2 NUPR2 Tbio Non-IDG -1.26245 15.0 0
Cell growth regulator with EF hand domain protein 1 CGREF1 Tbio Non-IDG -0.27619 2.01 143
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Junction-mediating and -regulatory protein JMY Tbio Non-IDG -1.26760 21.2 162
Growth arrest-specific protein 2 GAS2 Tbio Non-IDG -1.70451 49.0 218
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492