Development Level

Tbio 26 | 11,651
Tchem 14 | 1,388
Tclin 7 | 612
Tdark 2 | 6,593

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal seminal vesicle morph... 2 | 114
decreased circulating creatini... 2 | 39
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal colon morphology 1 | 3
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 65
abnormal testis morphology 1 | 43
decreased circulating insulin ... 1 | 76
decreased heart rate 1 | 18
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
polycystic kidney 1 | 15
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 31 | 11,493
osteosarcoma 28 | 7,950
ovarian cancer 27 | 8,520
Cancer 25 | 2,499
lung cancer 25 | 4,740
medulloblastoma, large-cell 25 | 6,241
psoriasis 25 | 6,694
non-small cell lung cancer 22 | 2,890
lung carcinoma 21 | 2,843
malignant mesothelioma 21 | 3,232
glioblastoma 20 | 5,792
invasive ductal carcinoma 19 | 2,951
Breast cancer 17 | 3,578
interstitial cystitis 17 | 2,312
ependymoma 16 | 4,679
lung adenocarcinoma 16 | 2,716
ulcerative colitis 16 | 1,819
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
cutaneous lupus erythematosus 13 | 1,057
subependymal giant cell astrocytoma 13 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
adrenocortical carcinoma 11 | 1,428
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
group 3 medulloblastoma 11 | 4,104
pancreatic cancer 11 | 2,398
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 10 | 3,801
oligodendroglioma 10 | 2,850
colon cancer 9 | 1,478
primitive neuroectodermal tumor 9 | 3,035
Breast Neoplasms 8 | 445
Kidney cancer 8 | 2,613
Rheumatoid arthritis 8 | 1,191
astrocytic glioma 8 | 2,597
gastric carcinoma 8 | 807
mucosa-associated lymphoid tissue lymphoma 8 | 484
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
primary Sjogren syndrome 8 | 735
tuberculosis 8 | 2,010
Liver Cirrhosis, Experimental 7 | 769
Schizophrenia 7 | 1,160
group 4 medulloblastoma 7 | 1,855
Carcinoma, Hepatocellular 6 | 228
Duchenne muscular dystrophy 6 | 601
Liver carcinoma 6 | 240
Mammary Neoplasms 6 | 425
astrocytoma 6 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,058
Asthma 5 | 385
Atopic dermatitis 5 | 952
Constipation 5 | 181
Endometriosis 5 | 540
Hypertension 5 | 396
Multiple Sclerosis 5 | 540
Neoplasm Metastasis 5 | 168
Pulmonary Fibrosis 5 | 106
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
urothelial carcinoma 5 | 318
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
Blastic phase chronic myeloid leukemia 4 | 58
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
Chronic phase chronic myeloid leukemia 4 | 45
Depressive disorder 4 | 409
Epilepsy 4 | 792
Hepatomegaly 4 | 285
Hypereosinophilic syndrome 4 | 71
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Liver cancer 4 | 604
Multiple, subcutaneous nodules 4 | 53
Nausea and vomiting 4 | 97
Neoplasm Invasiveness 4 | 161
Obesity 4 | 678
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Renal Cell Carcinoma 4 | 214
Small head 4 | 374
Stomach Neoplasms 4 | 300
Subcutaneous nodule 4 | 53
Vascular disease 4 | 319
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
aldosterone-producing adenoma 4 | 665
diabetes mellitus 4 | 1,728
hepatocellular carcinoma 4 | 547
medulloblastoma 4 | 720
esophageal adenocarcinoma 3 | 737
spina bifida 3 | 1,074

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Nervous System 46 | 16,725
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Respiratory system 45 | 16,393
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 21 | 12,091
GPCR 11 | 408
Kinase 10 | 634
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Transporter 1 | 473

GO Process

cell chemotaxis 49 | 49
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hepatocyte growth factor HGF Tchem Enzyme -3.30841 2392.1 724
Plexin-B3 PLXNB3 Tbio Non-IDG -0.99605 10.2 53
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
C-X-C motif chemokine 14 CXCL14 Tbio Non-IDG -2.42219 260.0 208
N-formyl peptide receptor 2 FPR2 Tchem GPCR -2.49147 330.9 253
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
C-C motif chemokine 25 CCL25 Tbio Non-IDG -1.79784 59.1 303
C-C chemokine receptor type 6 CCR6 Tchem GPCR -1.81445 63.7 519
Rho guanine nucleotide exchange factor 16 ARHGEF16 Tbio Non-IDG -2.37388 232.3 97