Development Level

Tbio 283 | 10,625
Tchem 70 | 1,890
Tdark 42 | 7,003
Tclin 14 | 602

Collection

Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 12 | 633
enlarged heart 6 | 111
abnormal sleep behavior 5 | 63
decreased circulating glucose ... 5 | 121
decreased grip strength 4 | 123
decreased total body fat amoun... 4 | 186
increased circulating alkaline... 4 | 119
increased circulating chloride... 4 | 43
increased exploration in new e... 4 | 56
increased or absent threshold ... 4 | 128
abnormal behavior 3 | 226
abnormal retina morphology 3 | 100
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased circulating choleste... 3 | 85
enlarged spleen 3 | 26
improved glucose tolerance 3 | 56
increased bone mineral density 3 | 52
increased circulating potassiu... 3 | 31
increased vertical activity 3 | 18
persistence of hyaloid vascula... 3 | 22
thrombocytopenia 3 | 46
tremors 3 | 34
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
abnormal response to new envir... 2 | 8
abnormal tooth morphology 2 | 24
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased body weight 2 | 174
decreased cervical vertebrae n... 2 | 12
decreased circulating amylase ... 2 | 24
decreased circulating insulin ... 2 | 75
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased leukocyte cell numbe... 2 | 54
decreased mature B cell number 2 | 25
decreased rib number 2 | 59
decreased vertical activity 2 | 22
edema 2 | 11
embryonic lethality prior to t... 2 | 187
impaired glucose tolerance 2 | 52
impaired righting response 2 | 19
increased NK T cell number 2 | 11
increased body weight 2 | 42
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
increased startle reflex 2 | 38
male infertility 2 | 62
preweaning lethality, incomple... 2 | 260
straub tail 2 | 26
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased Ly6C high monocyte n... 1 | 18
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased pulmonary respirator... 1 | 4
female infertility 1 | 34
hydrops fetalis 1 | 22
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating alanine ... 1 | 11
increased circulating iron lev... 1 | 25
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
premature death 1 | 5
prenatal lethality prior to he... 1 | 64

Disease

psoriasis 214 | 6,685
ovarian cancer 212 | 8,484
glioblastoma 192 | 5,572
osteosarcoma 192 | 7,933
medulloblastoma, large-cell 166 | 6,234
lung cancer 156 | 4,466
lung carcinoma 148 | 2,844
atypical teratoid / rhabdoid tumor 129 | 4,369
pilocytic astrocytoma 129 | 3,086
Carcinoma 127 | 2,147
interstitial cystitis 127 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 125 | 2,956
invasive ductal carcinoma 125 | 2,950
malignant mesothelioma 124 | 3,162
Cancer 123 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 121 | 2,988
lung adenocarcinoma 121 | 2,713
Breast cancer 119 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 116 | 3,289
non-small cell lung cancer 114 | 2,798
pancreatic cancer 114 | 2,300
pediatric high grade glioma 112 | 2,712
ulcerative colitis 93 | 2,087
oligodendroglioma 92 | 2,849
primary pancreatic ductal adenocarcinoma 89 | 1,271
primitive neuroectodermal tumor 85 | 3,031
cystic fibrosis 84 | 1,665
pituitary cancer 84 | 1,972
subependymal giant cell astrocytoma 81 | 2,287
ependymoma 77 | 2,514
breast carcinoma 71 | 1,614
gastric carcinoma 70 | 832
posterior fossa group A ependymoma 64 | 1,511
group 4 medulloblastoma 63 | 1,875
adult high grade glioma 62 | 2,148
ductal carcinoma in situ 62 | 1,745
tuberculosis 62 | 1,557
colon cancer 61 | 1,475
sonic hedgehog group medulloblastoma 61 | 1,482
adrenocortical carcinoma 60 | 1,427
astrocytoma 58 | 1,493
cutaneous lupus erythematosus 56 | 1,056
diabetes mellitus 54 | 1,663
astrocytic glioma 52 | 2,241
group 3 medulloblastoma 52 | 2,254
nasopharyngeal carcinoma 50 | 1,056
juvenile dermatomyositis 47 | 1,189
Duchenne muscular dystrophy 46 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 45 | 499
esophageal adenocarcinoma 45 | 737
Pick disease 43 | 1,893
Atopic dermatitis 39 | 944
medulloblastoma 38 | 1,524
posterior fossa group B ependymoma 38 | 1,530
Rheumatoid Arthritis 36 | 1,160
acute quadriplegic myopathy 36 | 1,157
mucosa-associated lymphoid tissue lymphoma 36 | 480
atypical teratoid/rhabdoid tumor 34 | 1,095
dermatomyositis 34 | 933
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
Multiple Sclerosis 31 | 498
fibroadenoma 31 | 557
primary Sjogren syndrome 28 | 789
urothelial carcinoma 26 | 318
Down syndrome 25 | 548
Alzheimer's disease 24 | 644
Becker muscular dystrophy 23 | 187
active Crohn's disease 23 | 918
interstitial lung disease 23 | 291
non-small cell lung carcinoma 23 | 413
spina bifida 23 | 1,064
Atherosclerosis 22 | 275
Kidney disease 22 | 396
Prostatic Neoplasms 22 | 471
aldosterone-producing adenoma 22 | 664
Endometriosis 21 | 535
Obesity 21 | 616
non primary Sjogren syndrome sicca 21 | 840
Asthma 20 | 349
progressive supranuclear palsy 20 | 674
Multiple myeloma 19 | 1,327
head and neck cancer 19 | 270
periodontitis 19 | 269
Coronary artery disease 18 | 240
Hypersensitivity reaction type II disease 18 | 235
head and neck cancer and chronic obstructive pulmonary disease 18 | 237
Heart disease 17 | 279
Intellectual disability 17 | 573
Mammary Neoplasms 17 | 410
active ulcerative colitis 17 | 477
Amyotrophic Lateral Sclerosis 16 | 431
Autistic Disorder 16 | 320
IGA Glomerulonephritis 16 | 454
Schizophrenia 16 | 501
Spontaneous abortion 16 | 108
Vascular disease 16 | 281
glioblastoma multiforme 16 | 347
limb girdle muscular dystrophy 2A 16 | 156
nephrosclerosis 16 | 329
pancreatic carcinoma 16 | 567

Tissue

Female tissues 406 | 18,647
Urinary Tract 405 | 18,444
Digestive Tract 404 | 18,473
Endocrine System 404 | 18,512
Liver and Pancreas 403 | 18,136
Male tissues 403 | 17,969
Nervous System 403 | 18,561
Cardiovascular System 401 | 17,958
Blood and immune system 400 | 17,995
Skin and soft tissues 400 | 18,115
Respiratory system 399 | 17,484

Target Family

Non-IDG 329 | 11,971
Enzyme 39 | 4,146
Kinase 18 | 634
GPCR 13 | 406
Transcription Factor 4 | 1,400
Transporter 4 | 473
Ion Channel 2 | 341

GO Process

cell adhesion 409 | 409
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Protein THEMIS2 THEMIS2 Tbio Non-IDG -1.15987 17.5 42
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.21530 0.00000 460
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.79457 669.7 172
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.73777 56.3 29
Contactin-associated protein-like 5 CNTNAP5 Tdark Non-IDG -0.52403 3.89 4