Development Level

Tbio 324 | 11,651
Tdark 70 | 6,593
Tchem 46 | 1,388
Tclin 18 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 9 | 499
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
abnormal behavior 5 | 298
abnormal sleep behavior 5 | 70
enlarged heart 5 | 210
increased startle reflex 5 | 112
decreased circulating glucose ... 4 | 126
decreased startle reflex 4 | 75
embryonic lethality prior to t... 4 | 278
improved glucose tolerance 4 | 79
increased circulating chloride... 4 | 41
increased heart weight 4 | 62
persistence of hyaloid vascula... 4 | 33
abnormal bone structure 3 | 187
abnormal lens morphology 3 | 81
abnormal retina morphology 3 | 71
decreased body weight 3 | 161
decreased circulating amylase ... 3 | 28
decreased circulating bilirubi... 3 | 19
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased leukocyte cell numbe... 3 | 73
edema 3 | 59
enlarged spleen 3 | 41
hydrometra 3 | 53
impaired glucose tolerance 3 | 75
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating triglyce... 3 | 42
increased hematocrit 3 | 46
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
increased vertical activity 3 | 24
small superior vagus ganglion 3 | 74
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal coat appearance 2 | 31
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal response to new envir... 2 | 10
abnormal retinal vasculature m... 2 | 27
abnormal skin morphology 2 | 50
abnormal tooth morphology 2 | 24
cataract 2 | 92
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
hemorrhage 2 | 23
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
male infertility 2 | 123
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
enlarged uterus 1 | 11
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
premature death 1 | 5
thin ventricular wall 1 | 24
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 367 | 11,493
psoriasis 229 | 6,694
ovarian cancer 225 | 8,520
glioblastoma 212 | 5,792
osteosarcoma 207 | 7,950
medulloblastoma, large-cell 178 | 6,241
lung cancer 175 | 4,740
lung carcinoma 162 | 2,843
ependymoma 160 | 4,679
atypical teratoid / rhabdoid tumor 159 | 5,112
Kidney cancer 157 | 2,613
Breast cancer 148 | 3,578
Astrocytoma, Pilocytic 135 | 3,081
adult high grade glioma 134 | 3,801
malignant mesothelioma 134 | 3,232
Cancer 133 | 2,499
interstitial cystitis 133 | 2,312
invasive ductal carcinoma 130 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 127 | 2,955
lung adenocarcinoma 127 | 2,716
non-small cell lung cancer 125 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 124 | 2,989
pancreatic cancer 124 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 120 | 3,291
group 3 medulloblastoma 115 | 4,104
oligodendroglioma 102 | 2,850
ulcerative colitis 92 | 1,819
primitive neuroectodermal tumor 89 | 3,035
cystic fibrosis 88 | 1,696
pituitary cancer 86 | 1,972
subependymal giant cell astrocytoma 82 | 2,287
primary pancreatic ductal adenocarcinoma 76 | 1,109
astrocytic glioma 75 | 2,597
tuberculosis 75 | 2,010
breast carcinoma 73 | 1,638
gastric carcinoma 68 | 807
group 4 medulloblastoma 68 | 1,855
ductal carcinoma in situ 64 | 1,745
colon cancer 63 | 1,478
adrenocortical carcinoma 60 | 1,428
Autosomal recessive predisposition 59 | 1,442
Liver cancer 59 | 604
cutaneous lupus erythematosus 59 | 1,057
diabetes mellitus 57 | 1,728
nasopharyngeal carcinoma 51 | 1,058
Melanoma 50 | 711
astrocytoma 48 | 1,146
juvenile dermatomyositis 48 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
pediatric high grade glioma 48 | 1,064
Pick disease 47 | 1,894
Duchenne muscular dystrophy 46 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 44 | 510
esophageal adenocarcinoma 44 | 737
Atopic dermatitis 43 | 952
Schizophrenia 43 | 1,160
Skin cancer 43 | 469
Rheumatoid arthritis 41 | 1,191
acute quadriplegic myopathy 37 | 1,158
mucosa-associated lymphoid tissue lymphoma 37 | 484
Liver Cirrhosis, Experimental 35 | 769
dermatomyositis 35 | 966
Multiple Sclerosis 33 | 540
fibroadenoma 32 | 559
Intellectual disability 28 | 1,016
Alzheimer's disease 27 | 658
primary Sjogren syndrome 27 | 735
spina bifida 27 | 1,074
urothelial carcinoma 27 | 318
Kidney disease 26 | 430
Asthma 25 | 385
Down syndrome 25 | 499
Endometrial cancer 25 | 311
active ulcerative colitis 25 | 764
medulloblastoma 25 | 720
Atherosclerosis 24 | 291
Muscle hypotonia 24 | 571
Obesity 24 | 678
active Crohn's disease 24 | 922
aldosterone-producing adenoma 24 | 665
Becker muscular dystrophy 23 | 191
Bipolar Disorder 23 | 666
Prostatic Neoplasms 23 | 495
non primary Sjogren syndrome sicca 23 | 891
periodontitis 23 | 293
interstitial lung disease 22 | 298
sonic hedgehog group medulloblastoma 22 | 467
Endometriosis 21 | 540
Epilepsy 21 | 792
limb girdle muscular dystrophy 2A 21 | 213
progressive supranuclear palsy 21 | 676
Breast Neoplasms 20 | 445
Hypertension 20 | 396
head and neck cancer 20 | 271
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
Short stature 19 | 531

Tissue

Endocrine System 448 | 18,159
Digestive Tract 439 | 17,369
Female tissues 439 | 17,400
Male tissues 431 | 17,142
Nervous System 431 | 16,725
Blood and immune system 430 | 16,909
Liver and Pancreas 428 | 16,750
Skin and soft tissues 428 | 17,230
Urinary Tract 420 | 16,678
Respiratory system 418 | 16,393
Cardiovascular System 385 | 15,192

Target Family

Non-IDG 373 | 12,091
Enzyme 40 | 4,145
Kinase 22 | 634
GPCR 13 | 408
Transcription Factor 4 | 1,400
Transporter 4 | 473
Ion Channel 2 | 344

GO Process

cell adhesion 458 | 458
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Contactin-associated protein-like 4 CNTNAP4 Tbio Non-IDG -0.73408 0.00000 148
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.46619 29.0 124