Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal eye morphology 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
improved glucose tolerance 1 | 79
increased heart weight 1 | 62

Disease

glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Atrial Fibrillation 2 | 124
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cardiomegaly 2 | 116
Diabetes Mellitus, Experimental 2 | 108
Duchenne muscular dystrophy 2 | 601
Glaucoma 2 | 239
Glaucoma, Open-Angle 2 | 11
Heart disease 2 | 306
Prostatic Neoplasms 2 | 495
Skeletal muscle hypertrophy 2 | 16
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
congenital generalized lipodystrophy 2 | 10
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
ulcerative colitis 2 | 1,819
Abnormal pigmentation 1 | 25
Acanthosis Nigricans 1 | 27
Advanced bone age 1 | 35
Asymmetric Septal Hypertrophy 1 | 7
Broad feet 1 | 19
Bronchiolitis 1 | 18
CREST Syndrome 1 | 16
Cardiomyopathy, Familial Hypertrophic, 1 1 | 6
Cerebellar Dysmetria 1 | 56
Childhood onset 1 | 38
Clonus 1 | 18
Decreased subcutaneous adipose tissue 1 | 13
Deglutition Disorders 1 | 132
Dental caries 1 | 164
Diffuse Scleroderma 1 | 7
Diffuse cutaneous systemic sclerosis 1 | 17
Dyspareunia 1 | 12
Dyspnea 1 | 76
Familial partial lipodystrophy 1 | 12
Familial primary pulmonary hypertension 1 | 11
Generalized hirsutism 1 | 36
Growth hormone excess 1 | 14
Hepatosplenomegaly 1 | 22
Hirsutism 1 | 47
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertriglyceridemia result 1 | 37
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Hypocalcemia 1 | 32
Hypotension, Orthostatic 1 | 18
Idiopathic pulmonary arterial hypertension 1 | 40
Impaired glucose tolerance 1 | 28
Infiltrate of lung 1 | 17
Insulin Resistance 1 | 72
Large hand 1 | 18
Lipodystrophy 1 | 40
Lytic lesion 1 | 32
Mucosal telangiectasiae 1 | 14
Muscle Cramp 1 | 55
Myalgia 1 | 54
Narrow foramen obturatorium 1 | 5
Oliguria 1 | 8
Ovarian Neoplasms 1 | 102
Pancreatitis 1 | 123
Precocious Puberty 1 | 28
Primary pulmonary hypertension 1 | 14
Prominent supraorbital ridges 1 | 19
Pulmonary Fibrosis 1 | 106
Pulmonary hypertension 1 | 85
Rotting teeth 1 | 73
Scleroderma, Limited 1 | 6
Serum cholesterol raised 1 | 22
Skin Ulcer 1 | 48
Steatohepatitis 1 | 44
Stevens-Johnson syndrome 1 | 92
Subaortic stenosis 1 | 9
Sudden infant death syndrome 1 | 32
Telangiectasia of the skin 1 | 39
Xerostomia 1 | 42
hypopigmented skin patch 1 | 59
limited scleroderma 1 | 19
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Nervous System 3 | 16,725

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145

GO Process

caveola assembly 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caveolin-2 CAV2 Tbio Non-IDG -2.43448 254.2 294
Protein kinase C and casein kinase substrate in neurons protein 2 PACSIN2 Tbio Enzyme -1.38534 27.2 135
Caveolin-1 CAV1 Tbio Non-IDG -3.35685 2432.3 855
Caveolin-3 CAV3 Tbio Non-IDG -2.58501 381.9 200