Development Level

Tbio 11 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged uterus 2 | 11
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal limb bud morphology 1 | 17
abnormal placenta size 1 | 20
abnormal skin morphology 1 | 50
abnormal urinary bladder morph... 1 | 11
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydrometra 1 | 53
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased or absent threshold ... 1 | 101
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 19 | 11,493
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
Kidney cancer 5 | 2,613
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
group 3 medulloblastoma 4 | 4,104
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Abnormality of retinal pigmentation 3 | 111
Blindness 3 | 88
Breast cancer 3 | 3,578
Difficulties with night vision 3 | 87
Electroretinogram abnormal 3 | 95
Night Blindness 3 | 101
Nystagmus 3 | 317
Photodysphoria 3 | 121
Photophobia 3 | 121
Pick disease 3 | 1,894
Retinal pigment epithelial abnormality 3 | 111
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Abnormal color vision 2 | 31
Achromatopsia 2 | 16
Achromatopsia 1 2 | 3
Achromatopsia 2 2 | 3
Bipolar Disorder 2 | 666
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Cardiovascular system disease 2 | 246
Cataract 2 | 297
Color vision defect 2 | 33
Color vision defect, severe 2 | 31
Cone dystrophy 2 | 71
Congenital nystagmus 2 | 26
Dull intelligence 2 | 645
Dyschromatopsia 2 | 8
Exotropia 2 | 35
Fundus dystrophy 2 | 83
General anesthesia 2 | 53
Hyperopia 2 | 70
Intellectual disability 2 | 1,016
Leber congenital amaurosis 2 | 69
Lens Opacities 2 | 231
Liver Cirrhosis, Experimental 2 | 769
Low Vision 2 | 174
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Nystagmus, continuous pendular 2 | 14
Obesity 2 | 678
Ophthalmoplegia 2 | 106
Pendular Nystagmus 2 | 14
Poor school performance 2 | 645
Prenatal onset 2 | 139
Retinal Degeneration 2 | 106
Retinitis Pigmentosa 2 | 226
Schizophrenia 2 | 1,160
Visual Impairment 2 | 174
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cone-rod dystrophy 2 | 59
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
Alcoholism 1 | 45
Arteriosclerotic Parkinsonism 1 | 8
Chronic Kidney Diseases 1 | 13
Frontal lobe epilepsy 1 | 10
Gastrointestinal stromal tumor 1 | 62
Glycoproteinosis 1 | 12
High pressure neurological syndrome 1 | 9
Influenza A Prevention 1 | 7
Influenza due to Influenza A virus 1 | 7
Leprosy 1 | 73
Neurilemmoma 1 | 23
Postencephalitic parkinsonism 1 | 12
Progressive renal failure 1 | 13
Reticulocytosis 1 | 20
Splenic infarction 1 | 6
Synovial sarcoma 1 | 25
Tachycardia, Ventricular 1 | 22
Visceral leishmaniasis 1 | 14

Tissue

Endocrine System 23 | 18,159
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Respiratory system 22 | 16,393
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Urinary Tract 20 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Ion Channel 20 | 344
Transporter 2 | 473
Non-IDG 1 | 12,091

GO Process

cation transport 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Anoctamin-10 ANO10 Tbio Non-IDG -1.22069 14.6 54
Calcium homeostasis modulator protein 1 CALHM1 Tbio Ion Channel -1.71853 53.7 94
Anoctamin-1 ANO1 Tclin Ion Channel -2.58674 414.4 565
Piezo-type mechanosensitive ion channel component 2 PIEZO2 Tbio Ion Channel -2.31598 196.2 140
Probable phospholipid-transporting ATPase VD ATP10D Tdark Transporter -0.59812 3.80 33